An Electroanalytical Flexible Biosensor Based on Reduced Graphene Oxide-DNA Hybrids for the Early Detection of Human Papillomavirus-16
Abstract
:1. Introduction
2. Experimental
2.1. Materials and Reagents
2.2. Synthesis of Reduced Graphene Oxide (rGO) Nanostructures
2.3. Characterization of rGO Nanostructures
2.4. Sensor Surface Fabrication
2.5. Electrochemical Analyses
3. Results and Discussion
3.1. Microstructural Surface Characterization
3.2. Response at Electrode Fabrication Stages
3.3. Optimization of CSPE/rGO/PDNA Based Genosensing Surface
3.4. HPV-16 Detection at CSPE/rGO/PDNA Electrodes
3.5. Selectivity, Real Sample and Shelf-Life Studies
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Rawat, R.; Roy, S.; Goswami, T.; Mathur, A. An Electroanalytical Flexible Biosensor Based on Reduced Graphene Oxide-DNA Hybrids for the Early Detection of Human Papillomavirus-16. Diagnostics 2022, 12, 2087. https://doi.org/10.3390/diagnostics12092087
Rawat R, Roy S, Goswami T, Mathur A. An Electroanalytical Flexible Biosensor Based on Reduced Graphene Oxide-DNA Hybrids for the Early Detection of Human Papillomavirus-16. Diagnostics. 2022; 12(9):2087. https://doi.org/10.3390/diagnostics12092087
Chicago/Turabian StyleRawat, Reema, Souradeep Roy, Tapas Goswami, and Ashish Mathur. 2022. "An Electroanalytical Flexible Biosensor Based on Reduced Graphene Oxide-DNA Hybrids for the Early Detection of Human Papillomavirus-16" Diagnostics 12, no. 9: 2087. https://doi.org/10.3390/diagnostics12092087