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Review

Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma

by
Abhirup Chatterjee
and
Jimil Shah
*
Department of Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012, India
*
Author to whom correspondence should be addressed.
Diagnostics 2024, 14(1), 78; https://doi.org/10.3390/diagnostics14010078
Submission received: 4 December 2023 / Revised: 26 December 2023 / Accepted: 27 December 2023 / Published: 28 December 2023
(This article belongs to the Special Issue Diagnostic Value of Endoscopic Ultrasound for Pancreatic Diseases)

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is the most common (90%) type of solid pancreatic neoplasm. Due to its late presentation and poor survival rate, early diagnosis and timely treatment is of utmost importance for better clinical outcomes. Endoscopic ultrasound provides high-resolution images of the pancreas and has excellent sensitivity in the diagnosis of even small (<2 cm) pancreatic lesions. Apart from imaging, it also has an advantage of tissue acquisition (EUS fine-needle aspiration, FNA; or fine-needle biopsy, FNB) for definitive diagnoses. EUS-guided tissue acquisition plays a crucial role in genomic and molecular studies, which in today’s era of personalized medicine, are likely to become important components of PDAC management. With the use of better needle designs and technical advancements, EUS has now become an indispensable tool in the management of PDAC. Lastly, artificial intelligence for the detection of pancreatic lesions and newer automated needles for tissue acquisition will obviate observer dependency in the near future, resulting in the wider dissemination and adoption of this technology for improved outcomes in patients with PDAC.
Keywords: PDAC; EUS; fine-needle aspiration (FNA); fine-needle biopsy (FNB); precision medicine; pancreatic carcinoma PDAC; EUS; fine-needle aspiration (FNA); fine-needle biopsy (FNB); precision medicine; pancreatic carcinoma

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MDPI and ACS Style

Chatterjee, A.; Shah, J. Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma. Diagnostics 2024, 14, 78. https://doi.org/10.3390/diagnostics14010078

AMA Style

Chatterjee A, Shah J. Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma. Diagnostics. 2024; 14(1):78. https://doi.org/10.3390/diagnostics14010078

Chicago/Turabian Style

Chatterjee, Abhirup, and Jimil Shah. 2024. "Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma" Diagnostics 14, no. 1: 78. https://doi.org/10.3390/diagnostics14010078

APA Style

Chatterjee, A., & Shah, J. (2024). Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma. Diagnostics, 14(1), 78. https://doi.org/10.3390/diagnostics14010078

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