Diagnostic Yield and Outcomes of Small Bowel Capsule Endoscopy in Patients with Small Bowel Bleeding Receiving Antithrombotics
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Definitions
2.3. Capsule Procedure
2.4. Endpoints
- To assess the diagnostic yield of SBCE among patients presenting with SBB.
- To assess the therapeutic intervention rate in patients with positive findings at SBCE.
- To assess the rebleeding rate in patients with SBB undergoing SBCE.
2.5. Statistical Analysis
3. Results
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Whole Population | Patients Receiving Antithrombotics | Patients Not Receiving Antithrombotics | p Value | |
---|---|---|---|---|
Age, mean (SD), years | 52.6 ± 27.3 | 56.1 ± 29.1 | 49.9 ± 25.4 | <0.0001 |
Sex, males/females, number of patients | 4360/4041 | 1302/1233 | 3058/2828 | 0.61 |
Comorbidities, n (%) | ||||
Hypertension | 2854 (33.9%) | 804 | 2050 | 0.006 |
Diabetes mellitus | 1982 (23.5%) | (31.7%) | (34.9%) | 0.05 |
Chronic kidney disease | 1077 (12.8%) | 631 | 1351 | 0.0009 |
Liver cirrhosis | 233 (2.8%) | (24.9%) | (23.0%) | <0.0001 |
Ischemic heart disease | 2106 (25.1%) | 278 | 801 | <0.0001 |
Hematologic disease | 349 (4.2%) | (10.9%) | (13.6%) | <0.0001 |
Whole Population (n = 8401) | Patients on Antithrombotics (n = 2535) | Patients without Antithrombotics (n = 5866) | p Value | |
---|---|---|---|---|
Overt Bleeding, n (%) | 2389 (28.4) | 963 (38) | 1426 (24.2) | <0.0001 |
Melena, n (%) | 1733 (20.6) | 647 (25.5) | 1086 (18.5) | <0.0001 |
Hematochezia, n (%) | 656 (7.8) | 316 (12.5) | 340 (5.8) | <0.0001 |
Occult bleeding, n (%) | 6012 (71.5) | 1572 (62) | 4440 (75.7) | <0.0001 |
Iron deficiency anemia, n (%) | 4396 (52.3) | 1127 (44.5) | 3269 (55.7) | <0.0001 |
Positive fecal occult blood testing, n (%) | 1616 (19.2) | 445 (17.6) | 1171 (20) | 0.01 |
Whole Population (n = 8401) | Patients on Antithrombotics (n = 2535) | Patients without Antithrombotics (n = 5866) | p Value | |
---|---|---|---|---|
P0 lesions, n (%) | 3976 (47.3%) | 723 (28.5) | 3253 (55.4) | <0.0001 |
P1 lesions, n (%) | 2209 (26.3%) | 709 (27.9) | 1500 (25.6) | 0.02 |
Isolated erosions or red spots | 1208 (14.3%) | 356 (14.1) | 852 (14.5) | 0.60 |
Venous ectasias | 864 (10.3) | 302 (11.9) | 562 (9.5) | 0.001 |
Small polyps or submucosal tumors | 137 (1.6%) | 51 (2.0) | 86 (1.4) | 0.07 |
P2 lesions, n (%) | 2216 (26.3%) | 1103 (43.5) | 1113 (18.9) | <0.0001 |
Mucosal breaks | 582 (6.9%) | 241 (9.5) | 341 (5.8) | <0.0001 |
Angiodysplasias | 1459 (17.4%) | 781 (30.8) | 678 (11.5) | <0.0001 |
Small bowel tumors | 175 (2.1%) | 81 (3.2) | 94 (1.6) | <0.0001 |
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Viazis, N.; Christodoulou, D.; Papastergiou, V.; Mousourakis, K.; Kozompoli, D.; Stasinos, G.; Dimopoulou, K.; Apostolopoulos, P.; Fousekis, F.; Liatsos, C.; et al. Diagnostic Yield and Outcomes of Small Bowel Capsule Endoscopy in Patients with Small Bowel Bleeding Receiving Antithrombotics. Diagnostics 2024, 14, 1361. https://doi.org/10.3390/diagnostics14131361
Viazis N, Christodoulou D, Papastergiou V, Mousourakis K, Kozompoli D, Stasinos G, Dimopoulou K, Apostolopoulos P, Fousekis F, Liatsos C, et al. Diagnostic Yield and Outcomes of Small Bowel Capsule Endoscopy in Patients with Small Bowel Bleeding Receiving Antithrombotics. Diagnostics. 2024; 14(13):1361. https://doi.org/10.3390/diagnostics14131361
Chicago/Turabian StyleViazis, Nikos, Dimitris Christodoulou, Vasilis Papastergiou, Konstantinos Mousourakis, Dimitra Kozompoli, Giannis Stasinos, Konstantina Dimopoulou, Periklis Apostolopoulos, Fotios Fousekis, Christos Liatsos, and et al. 2024. "Diagnostic Yield and Outcomes of Small Bowel Capsule Endoscopy in Patients with Small Bowel Bleeding Receiving Antithrombotics" Diagnostics 14, no. 13: 1361. https://doi.org/10.3390/diagnostics14131361