The Association between Specimen Neuromuscular Characteristics and Urinary Incontinence after Robotic-Assisted Radical Prostatectomy
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. Post-Surgery Continence
3.2. ICIQ Score and Patients’ Disease Features
3.3. Neuromuscular Characteristics
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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ICIQ Category (12 Months Post-Surgery) | Number of Patients (Percentage) | Early Full Continence—Number of Patients (6 Weeks Post-Surgery) (Percentage from the Group) | Erectile Preservation (Number of Patients with Preoperative Erectile Function) |
---|---|---|---|
Slight (1–5) | 9 (31%) | 4 (44%) | 2 (4) |
Moderate (6–12) | 9 (31%) | 2 (22%) | 1 (4) |
Severe and very severe (13–21) | 11 (38%) | 1 (9%) | 0 (4) |
ICIQ ≤ 12 (n = 18) | ICIQ > 12 (n = 11) | p Value | |
---|---|---|---|
Average ICIQ (IQR) | 6.5 (2.25–10.75) | 16.4 (14.5–18) | |
Age (IQR) | 67.3 (63.9–73.3) | 69.4 (67–72.7) | 0.44 |
Preoperative PSA (ng/mL) (IQR) | 9.1 (6.6–9.9) | 16 (9–22.2) | 0.02 |
Number of patients with preoperative LUTS (IPSS > 7) | 8 (45%) | 5 (45%) | 0.96 |
ISUP score | 0.302 | ||
1 | 1 (5.5%) | 0 (0%) | |
2 | 8 (44.4%) | 3 (27.2%) | |
3 | 5 (27.7%) | 4 (36.3%) | |
4 | 2 (11.1%) | 2 (18.1%) | |
5 | 2 (11.1%) | 0 (0%) | |
ISUPx—after hormonal treatment—2 (18.1%) | |||
Prostate size (gram) | 68 (55–73) | 63.2 (49.5–65.3) | 0.6 |
pT stage (2009) | 0.136 | ||
T2 | 8 (44.4%) | 1 (9%) | |
T3a | 9 (50%) | 9 (82%) | |
T3b | 1 (5.5%) | 1 (9%) | |
Full 6W continence day | 8 (45%) | 3 (27%) | 0.37 |
Full 6W continence night | 8 (45%) | 2 (18%) | 0.14 |
Overall (n = 29) | ICIQ Score ≤ 12 (n = 18) | ICIQ Score > 12 (n = 11) | p Value | |
---|---|---|---|---|
Presence of ganglion in the base, n (%) | 19 (65%) | 11 (61%) | 8 (72%) | 0.22 |
Presence of ganglion in the apex, n (%) | 12 (41%) | 8 (44%) | 4 (36%) | 0.11 |
Proportional area of detrusor muscle in the base, median (IQR) | 0.54 (0.31–1.00) | 0.45 (0.29–0.92) | 0.60 (0.40–1.00) | 0.57 |
Proportional area of striated muscle at the apex, median (IQR) | 0.13 (0.07–0.24) | 0.13 (0.06–0.24) | 0.13 (0.08–0.24) | 1.00 |
Number of nerves at the base, median (IQR) | 52 (13–139) | 69 (11–152) | 36 (14–108) | 0.65 |
Number of nerves at the apex, median (IQR) | 59 (28–129) | 61 (28–142) | 51 (33–116) | 0.46 |
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Bashi, T.; Margalioth, J.; Savin, Z.; Marom, R.; Dekalo, S.; Fahoum, I.; Naamneh, R.; Mano, R.; Yossepowitch, O. The Association between Specimen Neuromuscular Characteristics and Urinary Incontinence after Robotic-Assisted Radical Prostatectomy. Diagnostics 2024, 14, 2001. https://doi.org/10.3390/diagnostics14182001
Bashi T, Margalioth J, Savin Z, Marom R, Dekalo S, Fahoum I, Naamneh R, Mano R, Yossepowitch O. The Association between Specimen Neuromuscular Characteristics and Urinary Incontinence after Robotic-Assisted Radical Prostatectomy. Diagnostics. 2024; 14(18):2001. https://doi.org/10.3390/diagnostics14182001
Chicago/Turabian StyleBashi, Tomer, Jonathan Margalioth, Ziv Savin, Ron Marom, Snir Dekalo, Ibrahim Fahoum, Rabab Naamneh, Roy Mano, and Ofer Yossepowitch. 2024. "The Association between Specimen Neuromuscular Characteristics and Urinary Incontinence after Robotic-Assisted Radical Prostatectomy" Diagnostics 14, no. 18: 2001. https://doi.org/10.3390/diagnostics14182001