Retrospective Analysis of Omicron in Minas Gerais, Brazil: Emergence, Dissemination, and Diversification
Abstract
:1. Introduction
2. Materials and Methods
2.1. Genomic Surveillance Observatory and Study Design
2.2. Genotyping and SARS-CoV-2 Whole-Genome Sequencing
2.3. Phylogeographic Reconstructions
2.4. Epidemiological and Clinical Data Analysis
3. Results
3.1. Epidemiological Status of SARS-CoV-2 in MG State
3.2. Delta to Omicron Replacement and Its Sublineages in MG
3.3. Epidemiological Scenario during the Turnover of Variants and Subvariants
3.4. Omicron Lineages in Circulation in MG State
3.5. Omicron Introduction in MG State
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Lineages | |||||
Characteristic | Overall. N = 3.435 | No BA.2. N = 2.493 | BA.2. N = 351 | Delta. N = 591 | p-Value2 |
Sex | 0.152 | ||||
Female | 2.029 (59%) | 1.491 (60%) | 210 (60%) | 328 (55%) | |
Male | 1.406 (41%) | 1.002 (40%) | 141 (40%) | 263 (45%) | |
Death for SARS | 86 (2.5%) | 45 (1.8%) | 0 (0%) | 41 (6.9%) | <0.001 |
Age groups | 0.060 | ||||
>60 | 774 (23%) | 530 (21%) | 95 (27%) | 149 (25%) | |
0–29 | 885 (26%) | 657 (26%) | 84 (24%) | 144 (24%) | |
30–60 | 1.776 (52%) | 1.306 (52%) | 172 (49%) | 298 (50%) | |
Age groups | |||||
Characteristic | Overall. N = 3.482 | 0–29. N = 891 | 30–60. N = 1.798 | >60. N = 793 | p-Value2 |
Sex | <0.001 | ||||
Female | 2.055 (59%) | 525 (59%) | 1.127 (63%) | 403 (51%) | |
Male | 1.427 (41%) | 366 (41%) | 671 (37%) | 390 (49%) | |
Death for SARS | 86 (2.5%) | 1 (0.1%) | 13 (0.7%) | 72 (9.1%) | <0.001 |
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Fonseca, P.L.C.; Braga-Paz, I.; de Araújo e Santos, L.C.G.; Dias, R.C.; de Souza, C.S.A.; Carvalho, N.O.; Queiroz, D.C.; Alves, H.J.; de Araújo, J.L.F.; Moreira, F.R.R.; et al. Retrospective Analysis of Omicron in Minas Gerais, Brazil: Emergence, Dissemination, and Diversification. Microorganisms 2024, 12, 1745. https://doi.org/10.3390/microorganisms12091745
Fonseca PLC, Braga-Paz I, de Araújo e Santos LCG, Dias RC, de Souza CSA, Carvalho NO, Queiroz DC, Alves HJ, de Araújo JLF, Moreira FRR, et al. Retrospective Analysis of Omicron in Minas Gerais, Brazil: Emergence, Dissemination, and Diversification. Microorganisms. 2024; 12(9):1745. https://doi.org/10.3390/microorganisms12091745
Chicago/Turabian StyleFonseca, Paula Luize Camargos, Isabela Braga-Paz, Luiza Campos Guerra de Araújo e Santos, Rillery Calixto Dias, Carolina Senra Alves de Souza, Nara Oliveira Carvalho, Daniel Costa Queiroz, Hugo José Alves, João Locke Ferreira de Araújo, Filipe Romero Rebello Moreira, and et al. 2024. "Retrospective Analysis of Omicron in Minas Gerais, Brazil: Emergence, Dissemination, and Diversification" Microorganisms 12, no. 9: 1745. https://doi.org/10.3390/microorganisms12091745