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Microorganisms, Volume 12, Issue 9

September 2024 - 188 articles

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Cover Story: Borrelia burgdorferi, the agent of Lyme disease, has been shown to form antimicrobial-resistant biofilms, which protect microorganisms from adverse conditions. Bacterial biofilms are key factors in Lyme disease-related carditis. However, the role of B. burgdorferi biofilms in Lyme carditis remains unexplored due to the absence of a model. In this study, B. burgdorferi-infected mouse heart tissues were examined for biofilms and inflammatory markers using immunohistochemistry (IHC), FISH/IHC, and three-dimensional/atomic force microscopy. The results show that B. burgdorferi forms aggregates with a biofilm marker in mouse heart tissues, inducing inflammation through elevated C-reactive protein levels near biofilms. This mouse model can support future studies on B. burgdorferi biofilms. View this paper

Articles (188)

  • Review
  • Open Access
1 Citations
1,909 Views
18 Pages

Bacterial nanomachines represent remarkable feats of evolutionary engineering, showcasing intricate molecular mechanisms that enable bacteria to perform a diverse array of functions essential to persist, thrive, and evolve within ecological and patho...

  • Article
  • Open Access
2 Citations
2,963 Views
20 Pages

The utilization of agroindustrial residues, such as avocado peel, as a source of bioactive compounds with antioxidant properties has garnered significant attention. In this study, we investigated the antioxidant potential using the DPPH (2,2-diphenyl...

  • Article
  • Open Access
1 Citations
1,752 Views
17 Pages

In E. coli, transcriptional activation is often mediated by the C-terminal domain of RpoA, the α subunit of RNA polymerase. Random mutations that prevent activation of the arabinose PBAD promoter are clustered in the RpoA C-terminal domain (&al...

  • Article
  • Open Access
1 Citations
1,494 Views
17 Pages

Cephalostachyum pingbianense (Hsueh & Y.M. Yang ex Yi et al.) D.Z. Li & H.Q. Yang is unique among bamboo species for its ability to produce bamboo shoots in all seasons under natural conditions. Apart from the physiological mechanism, informa...

  • Review
  • Open Access
6 Citations
4,975 Views
13 Pages

Blastocystis is an anaerobic parasite that colonizes the intestinal tract of humans and animals. When it was first discovered, Blastocystis was considered to be a normal flora with beneficial effects on human health, such as maintaining gut hemostasi...

  • Review
  • Open Access
3 Citations
2,672 Views
16 Pages

Extrahepatic Cancer Risk in Patients with Hepatitis C Virus Infection Treated with Direct-Acting Antivirals

  • Joji Tani,
  • Tsutomu Masaki,
  • Kyoko Oura,
  • Tomoko Tadokoro,
  • Asahiro Morishita and
  • Hideki Kobara

Chronic hepatitis C virus (HCV) infection is associated with an increased risk of extrahepatic cancers, particularly non-Hodgkin lymphoma. The introduction of direct-acting antivirals (DAAs) has revolutionized HCV therapy, resulting in high cure rate...

  • Article
  • Open Access
1 Citations
1,492 Views
9 Pages

Changes in Cyanobacterial Phytoplankton Communities in Lake-Water Mesocosms Treated with Either Glucose or Hydrogen Peroxide

  • David Linz,
  • Charlyn G. Partridge,
  • Michael C. Hassett,
  • Nathan Sienkiewicz,
  • Katie Tyrrell,
  • Aimèe Henderson,
  • Renee Tardani,
  • Jingrang Lu,
  • Alan D. Steinman and
  • Stephen Vesper

When cyanobacterial phytoplankton form harmful cyanobacterial blooms (HCBs), the toxins they produce threaten freshwater ecosystems. Hydrogen peroxide is often used to control HCBs, but it is broadly toxic and dangerous to handle. Previously, we demo...

  • Article
  • Open Access
2 Citations
2,325 Views
14 Pages

Bioaerosol Inactivation by a Cold Plasma Ionizer Coupled with an Electrostatic Precipitator

  • Samuel Wei Yang Lim,
  • Sian Yang Ow,
  • Laura Sutarlie,
  • Yeong Yuh Lee,
  • Ady Suwardi,
  • Chee Kiang Ivan Tan,
  • Wun Chet Davy Cheong,
  • Xian Jun Loh and
  • Xiaodi Su

Despite best efforts in air purification, airborne infectious diseases will continue to spread due to the continuous emission of bioaerosols by the host/infected person. Hence, a shift in focus from air purification to bioaerosol inactivation is urge...

  • Review
  • Open Access
1 Citations
1,702 Views
9 Pages

Renal Actinomycosis in Humans—A Narrative Review

  • Ilias Giannakodimos,
  • Afroditi Ziogou,
  • Alexios Giannakodimos,
  • Evangelia Mitakidi,
  • Aris Kaltsas,
  • Zisis Kratiras and
  • Michael Chrisofos

Actinomycosis of the kidney is extremely rare, with only a few cases reported in the literature. This rare entity usually presents with common clinical manifestations and non-specific imaging findings, thus rendering its diagnosis extremely challengi...

  • Article
  • Open Access
1,643 Views
13 Pages

Supragingival Plaque Microbiomes in a Diverse South Florida Population

  • Sharlene Demehri,
  • Saynur Vardar,
  • Cristina Godoy,
  • Jose V. Lopez,
  • Paisley Samuel,
  • Toshihisa Kawai and
  • Andrew T. Ozga

Trillions of microbes comprise the human oral cavity, collectively acting as another bodily organ. Although research is several decades into the field, there is no consensus on how oral microbiomes differ in underrepresented groups such as Hispanic,...

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