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Review
Peer-Review Record

T-Cell Exhaustion in Mycobacterium tuberculosis and Nontuberculous Mycobacteria Infection: Pathophysiology and Therapeutic Perspectives

Microorganisms 2021, 9(12), 2460; https://doi.org/10.3390/microorganisms9122460
by Andrea Lombardi 1,2,*, Simone Villa 2, Valeria Castelli 1, Alessandra Bandera 1,2,3 and Andrea Gori 1,2,3
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Microorganisms 2021, 9(12), 2460; https://doi.org/10.3390/microorganisms9122460
Submission received: 10 November 2021 / Revised: 20 November 2021 / Accepted: 26 November 2021 / Published: 28 November 2021
(This article belongs to the Special Issue Old and New Challenges in Mycobacterium Infection Treatment)

Round 1

Reviewer 1 Report

In the article under review the authors analyze a very interesting and important for the disease outcome phenomenon immune exhaustion during chronic mycobacterial infections. The manuscript is well structured. The manuscript details the publications of recent years in this scientific area. The authors' original view of this problem is visible. Both the causes of exhaustion and the ways of solving this problem are analyzed in detail. This manuscript cold be recommended for publication as it is.

Author Response

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Author Response File: Author Response.pdf

Reviewer 2 Report

Excellent review article. In my opinion it is well structured and objective. I would like to point to the authors that in cases of NTM some patients clear infection on their own after adequate source control and this should be acknowledged ( https://www.sciencedirect.com/science/article/pii/S2214250921002882)

 

Author Response

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Author Response File: Author Response.pdf

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