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Article

Influences of Central Bouquet Alterations on the Visual Outcome in Eyes Receiving Epiretinal Membrane Surgery

by
Max Philipp Brinkmann
1,2,*,
Stephan Michels
2,3,
Carolin Brinkmann
4,
Mario Damiano Toro
2,5,*,
Nicole Graf Johansen
6,
Felix Rommel
4,
Mahdy Ranjbar
4 and
Matthias Becker
1,7
1
Department of Ophthalmology, Stadtspital Waid und Triemli Zürich, 8063 Zürich, Switzerland
2
Department of Ophthalmology, University of Zürich, 8091 Zürich, Switzerland
3
Augenklinik Zürich West, 8091 Zürich, Switzerland
4
Laboratory for Angiogenesis & Ocular Cell Transplantation, University of Lübeck, 23562 Lübeck, Germany
5
Faculty of Medical Sciences, Collegium Medicum, Cardinal Stefan Wyszyński University, 01815 Warsaw, Poland
6
Graf Biostatistics, 8400 Winterthur, Switzerland
7
Department of Ophthalmology, University of Heidelberg, 69117 Heidelberg, Germany
*
Authors to whom correspondence should be addressed.
Appl. Sci. 2021, 11(3), 926; https://doi.org/10.3390/app11030926
Submission received: 2 December 2020 / Revised: 16 January 2021 / Accepted: 16 January 2021 / Published: 20 January 2021
(This article belongs to the Special Issue Optical Coherence Tomography: From OCT-A to All Latest Advances)

Abstract

Background: Previous studies have shown that epiretinal membranes (ERMs) may be associated with abnormal outer retinal anatomy. However, long-term morphological and functional results of pars plana vitrectomy (PPV) with ERM and internal limiting membrane (ILM) peeling in eyes with central bouquet (CB) alterations have not yet been investigated. Methods: In a retrospective, consecutive study all patients underwent best corrected visual acuity (BCVA) testing and spectral domain optical coherence tomography (SD-OCT) before and after a mean of 20 months (range 3–70 months) postoperatively. CB abnormalities and ERMs were classified according to Govetto’s staging systems. Results: Of the 67 eyes, 22 (34%) showed CB abnormalities at baseline. The mean BCVA increased from 0.42 at baseline to 0.20 LogMAR at final follow-up (p < 0.001). Neither ERM stage (p = 0.06) nor CB stage (p = 0.939) at baseline were significant predictors of vision improvement following surgery. Conclusions: Our results show that baseline BCVA, but not classification of CB changes and ERM at baseline, seems to be a useful predictor for functional outcomes following PPV with ERM and ILM peeling in the long-term.
Keywords: acquired vitelliform lesion; epiretinal membrane; foveal bouquet; membrane peeling; predictive factor; pars plana vitrectomy acquired vitelliform lesion; epiretinal membrane; foveal bouquet; membrane peeling; predictive factor; pars plana vitrectomy

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MDPI and ACS Style

Brinkmann, M.P.; Michels, S.; Brinkmann, C.; Toro, M.D.; Johansen, N.G.; Rommel, F.; Ranjbar, M.; Becker, M. Influences of Central Bouquet Alterations on the Visual Outcome in Eyes Receiving Epiretinal Membrane Surgery. Appl. Sci. 2021, 11, 926. https://doi.org/10.3390/app11030926

AMA Style

Brinkmann MP, Michels S, Brinkmann C, Toro MD, Johansen NG, Rommel F, Ranjbar M, Becker M. Influences of Central Bouquet Alterations on the Visual Outcome in Eyes Receiving Epiretinal Membrane Surgery. Applied Sciences. 2021; 11(3):926. https://doi.org/10.3390/app11030926

Chicago/Turabian Style

Brinkmann, Max Philipp, Stephan Michels, Carolin Brinkmann, Mario Damiano Toro, Nicole Graf Johansen, Felix Rommel, Mahdy Ranjbar, and Matthias Becker. 2021. "Influences of Central Bouquet Alterations on the Visual Outcome in Eyes Receiving Epiretinal Membrane Surgery" Applied Sciences 11, no. 3: 926. https://doi.org/10.3390/app11030926

APA Style

Brinkmann, M. P., Michels, S., Brinkmann, C., Toro, M. D., Johansen, N. G., Rommel, F., Ranjbar, M., & Becker, M. (2021). Influences of Central Bouquet Alterations on the Visual Outcome in Eyes Receiving Epiretinal Membrane Surgery. Applied Sciences, 11(3), 926. https://doi.org/10.3390/app11030926

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