Round 1

Reviewer 1 Report

This systematic review focuses on an important and actual topic.

In general, the manuscript is well structured and written. There are small issues regarding English to be corrected. In the discussion the authors refer to periodontitis (lines 350 and 361) and periodontal tissues when I think they mean mucositis and peri-implant tissues.Otherwise, there are no major flaws to point out.

 

I think the article will be interesting for the readers and it is ready to be published after minor corrections

Author Response

Manuscript: Ref.: 2360573

Effect of adjunctive use of probiotics in the treatment of pe-ri-implant mucositis: A systematic review and meta-analysis

Journal: Appl Science

Reviewer 1

This systematic review focuses on an important and actual topic. In general, the manuscript is well-structured and written.

I think the article will be interesting for the readers and it is ready to be published after minor corrections.

Otherwise, there are no major flaws to point out.

 

Dear reviewer,

Thank you very much for the time employed in our manuscript. All suggestions and comments made were helpful in improving our text.

The revised manuscript includes changes to your comments (text in yellow) and a point-by-point response to each.

 

Questions:

1. There are small issues regarding English to be corrected.

 

Authors: Linguistic and academic editing was done by a native speaker

2. In the discussion, the authors refer to periodontitis (lines 350 and 361) and periodontal tissues when I think they mean mucositis and peri-implant tissues.

Authors: This was a writing error, and has been replaced in the text (lines 350 and 361) for mucositis and peri-implant tissue.

 

Author Response File: Author Response.docx

Reviewer 2 Report

This is an interesting manuscript. Very well written. The studies included ranged from 3-6 months for evaluation of clinical parameters. I have one suggestion that the long term use of probiotics as an adjunct to the conventional treatment of peri implant mucositis may be discussed!. Furthermore the influence of routine practices of oral hygiene measures should be emphasized.

 

Author Response

Manuscript: Ref.: 2360573

Effect of adjunctive use of probiotics in the treatment of pe-ri-implant mucositis: A systematic review and meta-analysis

Journal: Appl Science

This is an interesting manuscript. Very well written.

The studies included ranged from 3-6 months for evaluation of clinical parameters.

Dear reviewer,

Thank you very much for the time employed in our manuscript. All suggestions and comments made were helpful in improving our text.

The revised manuscript includes changes to your comments (text in yellow) and a point-by-point response to each.

 

Suggestion:

I have one suggestion that the long term use of probiotics as an adjunct to the conventional treatment of peri implant mucositis may be discussed!.

Furthermore the influence of routine practices of oral hygiene measures should be emphasized.

Authors: Dear reviewer, thank you for the suggestion. We have added a new paragraph to the discussion.

 

Line 399-403: In addition, the long-term use of probiotics as an adjuvant to conventional treatment for peri-implant mucositis can assist in reducing inflammation and controlling disease progression. Because probiotics can modulate the inflammatory response [18]. However, the effectiveness of the treatment will also depend on the level of oral hygiene since good oral hygiene is essential for maintaining oral health [33].

 

Author Response File: Author Response.docx

Reviewer 3 Report

The authors should present the results in a clearer and more concise manner, avoiding repeating all the information from the tables in the text. 

Author Response

Reviewer 3

Manuscript: Ref.: 2360573

Effect of adjunctive use of probiotics in the treatment of peri-implant mucositis: A systematic review and meta-analysis

Journal: Appl Science

This is an interesting manuscript.

Dear reviewer,

Thank you very much for the time employed in our manuscript.

Question

The authors should present the results in a clearer and more concise manner, avoiding repeating all the information from the tables in the text. 

Authors: Dear reviewer, thank you for the suggestion.

All the results found in this systematic review were also included in the main text, considering that readers often overlook supplementary material. In this way, we aim to ensure that the text is clear and explanatory, providing a comprehensive understanding of the results.

Author Response File: Author Response.docx