Next Article in Journal
Aromatic Herbs of the Lamiaceae Family as Functional Ingredients in Wheat Tortilla
Previous Article in Journal
Characterization of a Modified Clinical Linear Accelerator for Ultra-High Dose Rate Beam Delivery
 
 
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Assessing Effective Doses and Proposing DRLs for Pediatric CT Procedures in Madinah (Single Hospital), Saudi Arabia

1
Diagnostic Radiography Department, College of Applied Medical Sciences, Taibah University, Madinah 41477, Saudi Arabia
2
KSAMC—Maternity and Children Hospital, Madinah 42313, Saudi Arabia
*
Author to whom correspondence should be addressed.
Appl. Sci. 2024, 14(17), 7583; https://doi.org/10.3390/app14177583
Submission received: 14 July 2024 / Revised: 19 August 2024 / Accepted: 22 August 2024 / Published: 27 August 2024

Abstract

:
This study aims to assess effective radiation doses (EDs) for pediatric computed tomography (CT) procedures in Madinah (single hospital), Saudi Arabia, and propose diagnostic reference levels (DRLs) for these procedures. This retrospective study collected data from 600 pediatric patients who underwent five CT procedures. The data were categorized by the type of CT procedure and the age of the patients. EDs and proposed DRLs for the pediatric CT procedures were computed. The highest EDs were found for abdominal (6.3 mSv) and head (4.8 mSv) CT procedures in pediatric patients aged <1 year. DRLs of the CTDIvol and DLP for abdominal and head CT procedures in pediatric patients aged <1 year were 4.2 mGy, 94 mGy.cm and 25 mGy, 414 mGy.cm, respectively. Chest EDs had the lowest EDs among all pediatric CT procedures, with EDs of 1.93, 1.51, 1.91, and 2.05 mSv in patients aged <1, 1 ≤ to < 5, 5 ≤ to < 10, and 10 ≤ to ≤ 15 years, respectively. It can be concluded that optimization is required for abdominal and head CT procedures in pediatric patients aged <1 year. Frequent updates on ED and DRL calculations will help monitor radiation doses and minimize radiation risks for patients undergoing these procedures.

1. Introduction

Computed tomography (CT) is an effective diagnostic procedure used to image different body organs and diagnose pathologies. However, it is considered one of the most frequent and highest sources of ionizing radiation among diagnostic imaging modalities for patients undergoing these procedures and, consequently, for radiological staff [1,2,3,4].
The relationship between radiation dose and the response of body tissues (i.e., cancer risk) was introduced as an absolute or relative relationship. With the absolute relationship, the cancer risk of radiation is independent of the age of the exposed person (the same risk magnitude at any age), whereas with the relative relationship, the risk is dependent (children and elders at the highest radiation risk) [5,6].
Thus, it is essential to assess radiation dose and optimize these procedures, especially for pediatric patients. Young patients are more radiosensitive and have a longer life expectancy, which increases the probability of radiation-induced cancers [7,8,9]. Therefore, minimizing ionizing radiation exposure is necessary to avoid its adverse effects while maintaining acceptable image quality [10,11,12].
The amount of energy absorbed in the human body is significantly related to the type of radiation (e.g., X-rays, protons, and alpha particles). Thus, the radiation weighting factor for each type of radiation (WR) was introduced to quantify the energy absorbed in the human body from each type of radiation. X-rays and gamma-rays were given the lowest WR (i.e., WR = 1). The concept of an organ or tissue weighting factor (WT) was introduced to quantify the radiosensitivity (response of an organ or tissue to radiation) for each organ or tissue type [13]. One of the commonly used methods to assess radiation dose is the effective dose (ED). It represents the absorbed radiation energy in the whole body, from homogeneous and uniform radiation, multiplied by a WT for each organ or tissue [14,15]. ED can be assessed theoretically or experimentally. In addition, a valuable method that can be used to monitor radiation dose levels is the diagnostic reference levels (DRLs). DRLs were introduced in 1996 by the International Commission on Radiological Protection (ICRP), with guidelines updated in 2001 [16,17]. DRLs indicate when radiation doses are considered optimal. For CT procedures, DRL values are set at the 75th (local and national DRLs) or 50th (typical values for single facility DRLs) percentile of the distribution of the CT dose index (CTDIvol) or dose length product (DLP) [18,19].
The European Commission of Radiation Protection reported in the European guidelines on diagnostic reference levels (2018) that DRLs for radiological examination procedures were not established in many countries. In addition, dose optimization for pediatric patients is a demanding subject. Thus, this is the first study conducted to establish DRLs for pediatric patients who underwent CT procedures in Madinah. The national DRLs can then be derived and established through the integration of local DRLs. Moreover, DRL values are not permanent values; they should be revised and updated regularly, for example, every 3–5 years or when new imaging techniques or technologies are introduced [19,20,21].
This study aims to assess effective radiation doses (EDs) for pediatric computed tomography (CT) procedures in Madinah (single hospital), Saudi Arabia, and propose diagnostic reference levels (DRLs) for these procedures.

2. Methodology

2.1. Data Collection

In this retrospective study, data of 600 pediatric patients who underwent five different CT procedures were collected. These procedures included head, chest, abdominal, abdominal–pelvic (AP), and chest–abdominal–pelvic (CAP) CT procedures. The data were obtained from picture archiving and communication system (PACS). Incomplete procedures or data were excluded from the study. The data were categorized into groups according to the type of CT procedure and the age of the pediatric patients. A total of 30 pediatric cases were collected for each CT procedure and age category. The age categories were defined as follows: <1 year, 1 ≤ to < 5 years, 5 ≤ to < 10 years, and 10 ≤ to ≤ 15 years. All procedures were performed using Canon CT machine—Aquilion ONE—GENESIS SP Toshiba—Irvine, CA, USA) [22]. The CT machine and PACS underwent periodic quality control tests.

2.2. Dose Assessment

The effective dose was computed using conversion factor (CF) specific to pediatric CT procedures (Equation (1)). The used CFs for the age categories, <1 year, 1 ≤ to < 5 years, 5 ≤ to < 10 years, and 10 ≤ to ≤ 15 years, were reported in the AAPM report no.96 and ICRP publication 102 [23,24]. This approach is straightforward, quick, and offers a convenient means of estimating the effective dose for CT scans.
ED (mSv) = DLP (mGy.cm) × CF (mSv mGy−1 cm−1)

2.3. Data Analysis

Descriptive analysis was applied to extract pediatric patients’ mean, maximum (Max) and minimum (Min) age, and standard deviation (SD). EDs and DRLs for the pediatric CT procedures were calculated. Regarding the recommendation of ICRP publication 135, DRLs were set at the median values (50th percentiles) of the DRL quantities CTDIvol and DLP [19,25]. All calculations were performed using Microsoft Excel software—version 2407 (2022).

3. Results

Table 1 shows the patients’ age, and Table 2 shows the calculated EDs for the pediatric CT procedures.
Table 3 shows the proposed DRLs for the pediatric CT procedures obtained in this study.
Table 4, Table 5 and Table 6 shows comparisons between the results obtained in this study (i.e., EDs and DRLs) and results found in the literature.

4. Discussion

CT diagnostic procedures are considered one of the highest sources of ionizing radiation, posing risks to both patients and medical personnel. Therefore, it is essential to assess radiation dose to reduce the effects of ionizing radiation while maintaining acceptable CT image quality for precise diagnoses.
A simple and straightforward method to assess radiation dose for CT procedures is to multiply the DLP by a CF to obtain the ED. This allows for estimating the possible risks of CT radiation and can take a step forward to optimize radiation exposure levels and minimize its risks.
The results for EDs and DRLs were computed and shown in Table 2 and Table 3. Then, the results were compared with the values for EDs and DRLs found in the literature, as shown in Table 4, Table 5 and Table 6. In this study, the maximum ED values were found in head and abdominal CT procedures for patients aged <1 year, whereas the minimum values were found in chest CT procedures. The values of the CTDIvol and DLP for head CT procedures were higher than the other CT procedures among all pediatric age groups.
The high EDs for head CT procedures were reported by Huda and Vance (2007) and Aw-Zoretic et al. (2014) [40,41] for patients aged <1 year compared to older or adult patients. These reports highlighted a concern for the importance of radiation dose optimization for young patients, as they are more radiosensitive and have a longer life expectancy, which increases the probability of radiation-induced cancers. In this study, the results of EDs for head CT procedures for patients aged < 5 years were higher than that reported by the USA (1) [26], Malaysia [27], and the USA (3), but the results for older age groups were comparable with these studies [28].
The DRLs of the DLP for head CT procedures for patients aged <1 year were found to be higher than the DRLs mentioned in USA (2) [29], European [20], and German [34] reports but lower than the Japanese DRLs [33]. On the other hand, the DRLs of CTDIvol appeared to be comparable with those reported in the previous studies.
Similarly, high EDs for abdomen CT procedures for patients aged < 5 years were noticed when they were compared with EDs reported by the USA (4), Turkey, and the USA (1). The DRLs of the DLP and the CTDIvol for abdominal CT procedures for patients aged < 5 years were found to be lower than those reported in the international [36] and Chinese [37] DRL reports but higher than those reported in Franch DRLs [35]. However, the difference could be related to the CT protocol setting (axial or helical scan), parameter settings, and type of the CT machine.
Thus, the results obtained in this study for EDs and DRLs were found to be the same, lower, or higher than the values found in the literature. Nevertheless, the results for abdominal and head EDs and DRLs, when compared with the values found in the literature, show the necessity for radiation dose optimization for patients aged <1 year. In addition, the assessed radiation dose and the proposed DRLs can be guidelines for the optimization of pediatric CT procedures.
Even though most of the assessed EDs and DRLs were found to be low or the same compared to the values found in the literature, radiation dose optimization should continue to reduce radiation dose received by pediatric patients undergoing CT procedures. This can be achieved by the optimization of EDs and establishment of DRLs for these procedures. Moreover, the revision of CT protocols and parameters is recommended. However, setting an optimal CT protocol with high image quality was reported as a demanding technique due to the variation in pediatric patients’ size [42]. In addition, deep investigations could be valuable to find the effect of different pediatric genders on EDs and DRLs results.
There are some important caveats to the study that deserve mentioning. There were no age subgroups (e.g., for pediatric patients aged 1 to 12 months and 1 to 5 years) that reflected significant variations in pediatric patient size and weight within the same age group (i.e., the age categories used in this study), especially for the youngest age groups (<5 years old). This could affect the precision of the ED assessments for these age groups. However, the age group categories in this study were reported in the AAPM report no. 96 and ICRP publication 102 [23,24]. Nevertheless, it is suggested to add additional pediatric age group increments, such as months for newborns and years for children less than 5 years old. Additionally, different pediatric genders may need deeper investigation in future work to determine if the gender could affect the ED and DRL results. Finally, the risks associated with radiation doses were not calculated or estimated in this study. This could be performed as an extended future work to provide a more comprehensive understanding of the radiation risks for pediatric patients.

5. Conclusions

In this study, the results of EDs and DRLs from pediatric CT procedures indicated that ED and DRL values were the same, higher, or lower than the ED and DRL values found in the literature. The maximum ED values were found in abdominal and head CT procedures for patients aged <1 year, whereas the minimum values were found in chest CT procedures. The values of the CTDIvol and DLP for head CT procedures were higher than the other CT procedures among all pediatric age groups. Thus, ED and DRL optimization is required for abdominal and head CT procedures in pediatric patients aged <1 year.
The assessed radiation dose and the proposed DRLs can be guidelines for optimizing pediatric CT procedures. In addition, frequent updates on ED and DRL calculations for pediatric CT procedures will help monitor radiation doses and minimize radiation risks for patients undergoing these procedures.

Author Contributions

Conceptualization, K.M.A. and N.S.A. (Nadia S. Alraddadi); Validation, A.S.A., A.M.A., N.S.A. (Nawaf S. Alraddadi), A.A.A. and F.H.H.; Formal analysis, K.M.A.; Investigation, A.S.A., A.M.A., N.S.A. (Nawaf S. Alraddadi), A.A.A. and F.H.H.; Data curation, A.S.A., A.M.A., N.S.A. (Nawaf S. Alraddadi), A.A.A. and F.H.H.; Writing—original draft, K.M.A., F.H.A. and N.S.A. (Nadia S. Alraddadi); Writing—review & editing, F.A.A.; Visualization, F.H.A. and N.S.A. (Nadia S. Alraddadi); Supervision, K.M.A., F.H.A. and N.S.A. (Nadia S. Alraddadi); Project administration, K.M.A. All authors have read and agreed to the published version of the manuscript.

Funding

This research received no external funding.

Institutional Review Board Statement

The study was approved by the Institutional Review Board of King Salman bin Abdulaziz Medical City (IRB log No: 23-058)—3 December 2023.

Informed Consent Statement

Not applicable.

Data Availability Statement

The raw data supporting the conclusions of this article will be made available by the authors on request.

Acknowledgments

The authors would like to acknowledge the cooperation of the staff of KSAMC Review Board, General Directorate of Health Affairs, staff of the CT center, and PACS administrators at Madinah—Madinah/Saudi Arabia.

Conflicts of Interest

The authors declare that there are no conflicts of interest or financial benefits involved in this study that could influence this work’s outcomes and results.

References

  1. Health Risks from Exposure to Low Levels of Ionizing Radiation: BEIR VII Phase 2; The British Institute of Radiology: Washington, DC, USA, 2006; Volume 2, pp. 1–406.
  2. Smith-Bindman, R.; Lipson, J.; Marcus, R. Radiation Dose Associated with Common Computed Tomography Examinations and the Associated Lifetime Attributable Risk of Cancer. J. Vasc. Surg. 2010, 51, 783. [Google Scholar] [CrossRef]
  3. Ogbole, G. Radiation dose in paediatric computed tomography: Risks and benefits. Ann. Ibadan Postgrad. Med. 2011, 8, 118–126. [Google Scholar] [CrossRef] [PubMed]
  4. Hall, E.J.; Brenner, D.J. Cancer risks from diagnostic radiology. Br. J. Radiol. 2008, 81, 362–378. [Google Scholar] [CrossRef]
  5. Kellerer, A.M.; Nekolla, E.A.; Walsh, L. On the conversion of solid cancer excess relative risk into lifetime attributable risk. Radiat. Environ. Biophys. 2001, 40, 249–257. [Google Scholar] [CrossRef]
  6. Walsh, L.; Schneider, U. A method for determining weights for excess relative risk and excess absolute risk when applied in the calculation of lifetime risk of cancer from radiation exposure. Radiat. Environ. Biophys. 2013, 52, 135–145. [Google Scholar] [CrossRef] [PubMed]
  7. Hall, E.J. Radiation biology for pediatric radiologists. Pediatr. Radiol. 2009, 39, 57–64. [Google Scholar] [CrossRef]
  8. Miglioretti, D.L.; Johnson, E.; Williams, A.; Greenlee, R.T.; Weinmann, S.; Solberg, L.I.; Feigelson, H.S.; Roblin, D.; Flynn, M.J.; Vanneman, N.; et al. The use of computed tomography in pediatrics and the associated radiation exposure and estimated cancer risk. JAMA Pediatr. 2013, 167, 700–707. [Google Scholar] [CrossRef]
  9. Chodick, G.; Kim, K.P.; Shwarz, M.; Horev, G.; Shalev, V.; Ron, E. Radiation risks from pediatric computed tomography scanning. Pediatr. Endocrinol. Rev. 2009, 7, 29–36. [Google Scholar]
  10. Al Ewaidat, H.; Zheng, X.; Khader, Y.; Abdelrahman, M.; Alhasan, M.K.M.; Rawashdeh, M.A.; Al Mousa, D.S.; Alawneh, K.Z.A. Assessment of radiation dose and image quality of multidetector computed tomography. Iran. J. Radiol. 2018, 15, e59554. [Google Scholar] [CrossRef]
  11. Catalano, C.; Francone, M.; Ascarelli, A.; Mangia, M.; Iacucci, I.; Passariello, R. Optimizing radiation dose and image quality. Eur. Radiol. Suppl. 2007, 17, 26–32. [Google Scholar] [CrossRef]
  12. Honey, I.; Hogg, P. Balancing radiation dose and image quality in diagnostic imaging. Radiography 2012, 18, e1–e2. [Google Scholar] [CrossRef]
  13. Cember, H. Introduction to Health Physics, 4th ed.; McGraw Hill Medical: Chicago, IL, USA, 2009; ISBN 978-0-07-164323-8. [Google Scholar]
  14. McCollough, C.H.; Schueler, B.A. Calculation of effective dose. Med. Phys. 2000, 27, 828–837. [Google Scholar] [CrossRef] [PubMed]
  15. Hurwitz, L.M.; Yoshizumi, T.T.; Goodman, P.C.; Frush, D.P.; Nguyen, G.; Toncheva, G.; Lowry, C. Effective Dose Determination Using an Anthropomorphic Phantom and Metal Oxide Semiconductor Field Effect Transistor Technology for Clinical Adult Body Multidetector Array Computed Tomography Protocols. J. Comput. Assist. Tomogr. 2007, 31, 544–549. [Google Scholar] [CrossRef] [PubMed]
  16. Wall, B.F. Diagnostic reference levels—The way forward. Br. J. Radiol. 2001, 74, 785–788. [Google Scholar] [CrossRef] [PubMed]
  17. Wall, B.F.; Shrimpton, P.C. The Historical Development of Reference Doses in Diagnostic Radiology. Radiat. Prot. Dosimetry 1998, 80, 15–19. [Google Scholar] [CrossRef]
  18. Aloufi, K.M.; Alhazmi, F.H.; Abdulaal, O.M.; Qurashi, A.A. Towards the Establishment of Diagnostic Reference Levels in Saudi Arabia: Review and Opinion. Egypt. J. Radiat. Sci. Appl. 2021, 33, 65–76. [Google Scholar] [CrossRef]
  19. Vañó, E.; Miller, D.L.; Martin, C.J.; Rehani, M.M.; Kang, K.; Rosenstein, M.; Ortiz-López, P.; Mattsson, S.; Padovani, R.; Rogers, A. ICRP Publication 135: Diagnostic Reference Levels in Medical Imaging. Ann. ICRP 2017, 46, 15–40. [Google Scholar] [CrossRef] [PubMed]
  20. European Commission. Radiation Protection N° 185 European Guidelines on Diagnostic Reference Levels; European Commission: Brussels, Belgium, 2018; ISBN 9789279863042. [Google Scholar]
  21. Bos, D.; Zensen, S.; Opitz, M.K.; Haubold, J.; Nassenstein, K.; Kinner, S.; Schweiger, B.; Forsting, M.; Wetter, A.; Guberina, N. Diagnostic reference levels for chest computed tomography in children as a function of patient size. Pediatr. Radiol. 2022, 52, 1446–1455. [Google Scholar] [CrossRef]
  22. Canon Aquilion One—GENESIS Edition. Available online: https://us.medical.canon/products/computed-tomography/aquilion-one-genesis/ (accessed on 1 July 2024).
  23. Annals of the ICRP Publication 102: Managing Patient Dose in Multi-Detector Computed Tomography (MDCT); SAGE Publications: Los Angeles, CA, USA, 2007; Volume 37, ISBN 9780702030475.
  24. McCollough, C.; Cody, D.; Edyvean, S.; Geise, R.; Gould, B.; Keat, N.; Huda, W.; Judy, P.; Kalender, W.; McNitt-Gray, M.; et al. The Measurement, Reporting, and Management of Radiation Dose in CT; American Association of Physicists in Medicine: Alexandria, VA, USA, 2008. [Google Scholar]
  25. Damilakis, J.; Frija, G.; Brkljacic, B.; Vano, E.; Loose, R.; Paulo, G.; Brat, H.; Tsapaki, V. How to establish and use local diagnostic reference levels: An ESR EuroSafe Imaging expert statement. Insights Imaging 2023, 14, 1–6. [Google Scholar] [CrossRef] [PubMed]
  26. Kharbanda, A.B.; Krause, E.; Lu, Y.; Blumberg, K. Analysis of radiation dose to pediatric patients during computed tomography examinations. Acad. Emerg. Med. 2015, 22, 670–675. [Google Scholar] [CrossRef]
  27. Muhammad, N.A.; Abdul Karim, M.K.; Abu Hassan, H.; Ahmad Kamarudin, M.; Ding Wong, J.H.; Ng, K.H. Diagnostic Reference Level of Radiation Dose and Image Quality among Paediatric CT Examinations in A Tertiary Hospital in Malaysia. Diagnostics 2020, 10, 591. [Google Scholar] [CrossRef] [PubMed]
  28. Gao, Y.; Quinn, B.; Pandit-Taskar, N.; Behr, G.; Mahmood, U.; Long, D.; Xu, X.G.; St. Germain, J.; Dauer, L.T. Patient-specific organ and effective dose estimates in pediatric oncology computed tomography. Phys. Medica 2018, 45, 146–155. [Google Scholar] [CrossRef] [PubMed]
  29. Kanal, K.M.; Butler, P.F.; Chatfield, M.B.; Wells, J.; Samei, E.; Simanowith, M.; Golden, D.; Gress, D.A.; Burleson, J.; Sensakovic, W.F.; et al. U.S. Diagnostic Reference Levels and Achievable Doses for 10 Pediatric CT Examinations. Radiology 2022, 302, 164–174. [Google Scholar] [CrossRef]
  30. Huda, W.; Atherton, J.V.; Ware, D.E.; Cumming, W.A. An approach for the estimation of effective radiation dose at CT in pediatric patients. Radiology 1997, 203, 417–422. [Google Scholar] [CrossRef]
  31. Atac, G.K.; Parmaksiz, A.; Inal, T.; Bulur, E.; Bulgurlu, F.; Oncu, T.; Gundogdu, S. Patient doses from CT examinations in Turkey. Diagnostic Interv. Radiol. 2015, 21, 428–434. [Google Scholar] [CrossRef]
  32. Pages, J.; Buls, N.; Osteaux, M. CT doses in children: A multicentre study. Br. J. Radiol. 2003, 76, 803–811. [Google Scholar] [CrossRef] [PubMed]
  33. Japan Network for Research and Information on Medical Exposure (J-RIME). National Diagnostic Reference Levels in Japan (2020). Available online: https://j-rime.qst.go.jp/report/DRL2020_Engver.pdf (accessed on 24 June 2024).
  34. Schegerer, A.; Loose, R.; Heuser, L.J.; Brix, G. Diagnostic Reference Levels for Diagnostic and Interventional X-Ray Procedures in Germany: Update and Handling. RöFo—Fortschritte Geb. Röntgenstrahlen Bildgeb. Verfahr. 2019, 191, 739–751. [Google Scholar] [CrossRef]
  35. Ducou-le-pointe, H.; Payen-de-la-garanderie, J.; Thierry-chef, I. Individual radiation exposure from computed tomography: A survey of paediatric practice in French university hospitals, 2010–2013. Eur. Soc. Radiol. 2017, 28, 630–641. [Google Scholar]
  36. Vassileva, J.; Rehani, M.; Kostova-Lefterova, D.; Al-Naemi, H.M.; Al Suwaidi, J.S.; Arandjic, D.; Bashier, E.H.O.; Kodlulovich Renha, S.; El-Nachef, L.; Aguilar, J.G.; et al. A study to establish international diagnostic reference levels for paediatric computed tomography. Radiat. Prot. Dosimetry 2015, 165, 70–80. [Google Scholar] [CrossRef]
  37. Yang, F.; Gao, L. Age-based diagnostic reference levels and achievable doses for paediatric CT: A survey in Shanghai, China. J. Radiol. Prot. 2024, 44, 021509. [Google Scholar] [CrossRef]
  38. Rawashdeh, M.; Abdelrahman, M.; Zaitoun, M.; Saade, C.; Alewaidat, H.; McEntee, M.F. Diagnostic reference levels for paediatric CT in Jordan. J. Radiol. Prot. 2019, 39, 1060–1073. [Google Scholar] [CrossRef] [PubMed]
  39. van der Merwe, C.M.; Mahomed, N. An audit of radiation doses received by paediatric patients undergoing computed tomography investigations at academic hospitals in South Africa. S. Afr. J. Radiol. 2020, 24, 1–8. [Google Scholar] [CrossRef] [PubMed]
  40. Huda, W.; Vance, A. Patient Radiation Doses from Adult and Pediatric CT. Am. J. Roentgenol. 2007, 188, 540–546. [Google Scholar] [CrossRef] [PubMed]
  41. Aw-Zoretic, J.; Seth, D.; Katzman, G.; Sammet, S. Estimation of effective dose and lifetime attributable risk from multiple head CT scans in ventriculoperitoneal shunted children. Eur. J. Radiol. 2014, 83, 1920–1924. [Google Scholar] [CrossRef]
  42. Buty, M.; Xu, Z.; Wu, A.; Gao, M.; Nelson, C.; Papadakis, G.Z.; Teomete, U.; Celik, H.; Turkbey, B.; Choyke, P.; et al. Quantitative Image Quality Comparison of Reduced- and Standard-Dose Dual-Energy Multiphase Chest, Abdomen, and Pelvis CT. Tomography 2017, 3, 114–122. [Google Scholar] [CrossRef]
Table 1. Pediatric age distributions for CT procedures.
Table 1. Pediatric age distributions for CT procedures.
CT ProcedureAge (Years)Average MaxMinSD
Head<10.350.920.0060.27
1 ≤ to < 52.5411.12
5 ≤ to < 107951.35
10 ≤ to ≤ 151214101.14
Chest<10.190.80.0080.21
1 ≤ to < 52.5411.04
5 ≤ to < 107.2951.28
10 ≤ to ≤ 1511.814101.28
Abdomen<10.40.90.0190.31
1 ≤ to < 52.8411.09
5 ≤ to < 106.8941.36
10 ≤ to ≤ 1511.513100.91
AP<10.280.90.0030.33
1 ≤ to < 52.9410.99
5 ≤ to < 107.8961.14
10 ≤ to ≤ 1512.514111.05
CAP<10.340.90.0190.28
1 ≤ to < 52.9410.96
5 ≤ to < 107.2951.31
10 ≤ to ≤ 1511.814101.15
Table 2. Calculated EDs for the pediatric CT procedures.
Table 2. Calculated EDs for the pediatric CT procedures.
CT ProcedureAge (Years)ED (mSv)
AverageMaxMinSD
Head<14.810.123.71.4
1 ≤ to < 53.646.62.871
5 ≤ to < 102.54.50.4161
10 ≤ to ≤ 152.966.90.841.4
Chest<11.934.490.641
1 ≤ to < 51.514.420.60.9
5 ≤ to < 101.913.240.880.8
10 ≤ to ≤ 152.054.780.80.8
Abdomen<16.317.81.673.5
1 ≤ to < 54.48.42.371.6
5 ≤ to < 103.846.12.081.2
10 ≤ to ≤ 152.774.981.551.1
AP<14.035.881.10.9
1 ≤ to < 54.612.662.682.1
5 ≤ to < 103.847.241.361.4
10 ≤ to ≤ 153.24.951.850.8
CAP<13.496.471.641.3
1 ≤ to < 54.576.221.121.1
5 ≤ to < 104.076.372.71.1
10 ≤ to ≤ 154.025.942.621.1
Table 3. The 25th, 50th, and 75th percentiles for the pediatric CT procedures included in this study.
Table 3. The 25th, 50th, and 75th percentiles for the pediatric CT procedures included in this study.
CTDIvol (mGy)DLP (mGy.cm)
CT ProcedureAge (Years)25th50th75th MinMaxSD25th50th75thMinMaxSD
Head<1252525.851256.55379.3414440920337.6131
1 ≤ to < 5252525.851.6257.8479505564984.6427153
5 ≤ to < 10303030.26019.711.6510.76046601125104240
10 ≤ to ≤ 1530.25353.4106.82622.5619.4103110992305281462
Chest<11.452.62.63.50.10.8332.6544.962.711516.526
1 ≤ to < 51.52.62.76.21.21.0633.9557.4561.81702335.7
5 ≤ to < 102.8253.154.15.82.41.0272.0395.5514018048.542.2
10 ≤ to ≤ 154.2254.655.1810.42.91.43130.516017836861.359
Abdomen<13.74.25.2181.723.8183941703643471.7
1 ≤ to < 53.744.283.31.35117.71271592807954
5 ≤ to < 1044.27.058.32.71.81151.5175.524130510458.8
10 ≤ to ≤ 153.253.654.257.32.91.45146.5154.517933210369.9
AP<13.73.73.741.10.497576.659312022.418.3
1 ≤ to < 53.744132.82.1116.5130.214742289.468.8
5 ≤ to < 1044.37.258.13.71.7150.5163.52303626869.7
10 ≤ to ≤ 153.7754.55.137.93.11.15165210.226033012354.6
CAP<12.5253.53.742.10.6646.28389.614737.230.3
1 ≤ to < 53.53.84.084.41.230.79155.8176.51842224039
5 ≤ to < 104.35.97.29.53.71.87171.7190.1235335141.656.8
10 ≤ to ≤ 154.25.458.0311.23.22.56200.126537542418781
Table 4. Comparisons between the calculated EDs for the pediatric CT procedures in this study and EDs found in the literature.
Table 4. Comparisons between the calculated EDs for the pediatric CT procedures in this study and EDs found in the literature.
CT ProcedureStudyAge (Years, mSv)
<11 ≤ to < 55 ≤ to < 1010 ≤ to ≤ 15
HeadThis study4.83.642.52.96
USA (1) [26]4.013.172.432.58
Malaysian [27]2.41.51.73.3
USA (3) [28]1.92.43.13.5
ChestThis study1.931.511.912.05
Malaysia [27]11.42.53.1
USA (2) [29]2.93.33.75.1
USA (3) [28]1.33.543.9
AbdomenThis study6.34.43.842.77
USA [4,30]5.34.23.73.7
Turkey [31]3.12.52.73.1
USA (1) [26]3.673.333.618.06
APThis study4.034.63.843.2
USA (2) [29]4.24.65.88.9
Belgium [32]4.565.045.06
USA (3) [28]2.86.26.88.1
CAPThis study3.494.574.074.02
USA (2) [29]4.44.44.78
USA (3) [28]4.37.27.710.8
Malaysia [27]1.82.95.811.1
Table 5. Comparisons between the proposed DRLs for the CTDIvol and the DRLs found in the literature.
Table 5. Comparisons between the proposed DRLs for the CTDIvol and the DRLs found in the literature.
CT ProcedureStudyAge (Years, CTDIvol)
<11 ≤ to < 55 ≤ to < 1010 ≤ to ≤ 15
HeadThis study25253053
USA (2) [29]23-
Europe [20]24284050
Japan [33]30405560
Germany [34]30355055
ChestThis study2.62.63.154.65
USA (2) [29]1.62.42.97.2
Europe [20]1.41.82.73.7
Japan [33]346.56.5
Germany [34]-2.646.5
France [35]2224
AbdomenThis study4.244.23.65
France [35]4367
International [36]5.277.89.8
China [37]6.34.28.215.5
APThis study3.744.34.5
USA (2) [29]2.42.94.67.9
Europe [20]5.47.3
Japan [33]567.59
Germany [34]57
CAPThis study3.53.85.95.45
USA (2) [29]2.734.39.1
Malaysia [27]34.67.111.7
Jordan [38]9.712.29.7
South Africa [39]566
Table 6. Comparisons between the proposed DRLs for the DLP and the DRLs found in the literature.
Table 6. Comparisons between the proposed DRLs for the DLP and the DRLs found in the literature.
CT ProcedureStudyAge (Years, DLP)
<11 ≤ to < 55 ≤ to < 1010 ≤ to ≤ 15
HeadThis study4145056041031
USA (2) [29]344
Europe [20]385505
Japan [33]4806608501000
Germany [34]300450650800
ChestThis study44.957.4595.55160
USA (2) [29]60110
Europe [20]
Japan [33]7095175230
Germany [34]55110200
France [35]264056116
AbdomenThis study94127175.5154.5
France [35]6577164258
International [36]130250310460
China [37]181.1258347.9556.8
APThis study76.65130.2163.5210.2
USA (2) [29]60100170368
Europe [20]150210
Japan [33]110190265450
Germany [34]185310
CAPThis study83176.5190.1265
USA (2) [29]89109204437
Malaysia [27]98.1150.2292.6644.9
Jordan [38]248.4530524
South Africa [39]215235285
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

Share and Cite

MDPI and ACS Style

Aloufi, K.M.; Alhazmi, F.H.; Alrehily, F.A.; Alraddadi, N.S.; Alharbi, A.S.; Alamin, A.M.; Alraddadi, N.S.; Alenezi, A.A.; Hadi, F.H. Assessing Effective Doses and Proposing DRLs for Pediatric CT Procedures in Madinah (Single Hospital), Saudi Arabia. Appl. Sci. 2024, 14, 7583. https://doi.org/10.3390/app14177583

AMA Style

Aloufi KM, Alhazmi FH, Alrehily FA, Alraddadi NS, Alharbi AS, Alamin AM, Alraddadi NS, Alenezi AA, Hadi FH. Assessing Effective Doses and Proposing DRLs for Pediatric CT Procedures in Madinah (Single Hospital), Saudi Arabia. Applied Sciences. 2024; 14(17):7583. https://doi.org/10.3390/app14177583

Chicago/Turabian Style

Aloufi, Khalid M., Fahad H. Alhazmi, Faisal A. Alrehily, Nadia S. Alraddadi, Ahmed S. Alharbi, Amjad M. Alamin, Nawaf S. Alraddadi, Abaad A. Alenezi, and Fai H. Hadi. 2024. "Assessing Effective Doses and Proposing DRLs for Pediatric CT Procedures in Madinah (Single Hospital), Saudi Arabia" Applied Sciences 14, no. 17: 7583. https://doi.org/10.3390/app14177583

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop