High-Speed Cell Assembly with Piezo-Driven Two-Finger Microhand

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

Dear Authors, 

The manuscipt should be revised before it is published. My comments and questions are listed in the attachment.

Kind Regards

Comments for author File: Comments.pdf

Comments on the Quality of English Language

English should be polished. 

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors

Introduction:

·       More clearly highlight the gaps in current cell micromanipulation techniques that this research aims to address

·       Provide more context on how this work builds on and advances prior literature in the field

 

Methods:

·       Include more details on the microhand design process and optimization

·       Test grasping/releasing parameters directly with cells rather than microspheres first

·       Elaborate on the image processing and recognition algorithms used

·       Provide more information on how optimal release conditions were determined

 

Results:

·       Present quantitative statistics on success rates over multiple trials to validate grasping, releasing, and assembly

·       Conduct cell viability assays after manipulation to assess if it causes damage

·       Provide more details on the robustness and speed of the automated visual feedback

 

Discussion:

·       Discuss limitations of the current system and work that still needs to be done

·       Elaborate on future directions for enhancing the microhand design and automation

·       Critically analyze how well the system meets the goals outlined in the introduction

 

Conclusions:

·       Summarize how the key results address the gaps identified in the introduction

·       Discuss potential new applications enabled by the robotic cell assembly system

·       Reiterate the most significant advances and innovations presented in the research

 

Broader Considerations:

·       Carefully proofread the paper to fix any grammar/spelling errors

·       Improve clarity and concision of the writing throughout

·       Ensure effective use of visuals to convey key information

·       Adhere to relevant guidelines for scientific publishing

Comments on the Quality of English Language

Abstract:

·       Line 10: "article" should be "paper" or "study"

·       Line 25: Insert "an" before "assembly accuracy"

Introduction:

·       Line 31: Replace "laws of life" with "mechanisms of life"

·       Line 34: Change "IVF (In Vitro Fertilization)" to "in vitro fertilization (IVF)"

·       Line 41: Replace "methods capable of" with "methods that can"

Methods:

·       Line 96: Change heading to "Two-Finger Microhand Structure"

·       Line 105: Replace "joint structure" with "joint design"

·       Line 172: Change "transitioning" to "transitioned"

Results:

·       Line 186: Replace "through" with "in"

·       Line 229: Fix typo in heading "Operation path planning"

·       Line 277: Change "asm" to "assemble" in the figure

Discussion:

·       Line 316: Change "laying the foundation for" to "enabling"

·       Lines 317-318: Delete extra "subsequent"

Conclusions:

·       Line 301: Change "methods heavily rely" to "methods currently heavily rely"

General:

·       Check for consistent verb tenses in different sections

·       Improve paragraph transitions between different subsections

·       Avoid overuse of the word "research" when referring to this study

·       Double check that all terms and acronyms are defined properly

 

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Round 2

Reviewer 1 Report

Comments and Suggestions for Authors

Dear Authors,

I do not have any further questions related to the revised version of the manuscript. The manuscript can be published after minor revision (methodological errors and text editing)

Kind Regards

Comments on the Quality of English Language

English is fine

Author Response

Dear Reviewer,

Many thanks for your effort in helping us improve the manuscript. We have completed the minor editing of English language in our manuscript. The modified parts have been highlighted in green in the revised manuscript. Thank you again for your valuable suggestions.

Kind Regards