Influence of Epilepsy Characteristics on the Anxiety Occurrence
Abstract
:1. Introduction
2. Methods
2.1. Study Population
2.2. Neurological Assessment
2.3. Psychological Assessment
2.4. Statistical Analysis
3. Results
3.1. Patients Sociodemographic and Clinical Data
3.2. Higher HAM-A Score in Patients with DRE
3.3. The Influence of Illness Duration, Drug Responsivity, and Epilepsy Type on Anxiety in Patients with Drug-Resistant Epilepsy
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variables | DSE Group | DRE Group | p |
---|---|---|---|
Age (years) | 38.18 ± 16.43 | 35.61 ± 12.52 | p = 0.659 |
Sex (male/female) | 27/25 | 50/53 | p = 0.820 |
Mean duration in illneses (years) | 9.56 ± 7.31 | 10.48 ± 758 | p = 0.459 |
Genelalized epilepsy | 23 (44.2%) | 48 (46.6%) | p = 0.913 |
Focal epilepsy | 29 (55.8%) | 53 (53.4%) | |
Temporal | 17 (58.6%) | 33 (59.3%) | |
Frontal | 11(37.9%) | 16 (29.8%) | |
Parietal | / | 2 (3.6%) | |
Occipital | 1 (3.4%) | 4 (7.3%) | |
Poor seizure control | / | 25 (24.3%) | |
Medium seizure control | / | 63 (61.2%) | |
Good seizure control | 12 (23.1%) | 9 (8.7%) | |
Rare seizures | 12 (23.1%) | 5 (4.9%) | |
Remmision | 28 (53.8%) | 1 (0.9%) | |
Monotherapy | 52 (100) | / | |
Duotherapy | / | 73 (70.9%) | |
Polytherapy | / | 30 (29.1%) | |
Topiramate | 5 (9.6%) | 23 (23.3%) | |
Levetiracetam | 20 (38.5%) | 97 (94.2%) | |
Carbamazepine | 12 (23.1%) | 44 (42.7%) | |
Phenobarbiton | 2 (3.8%) | 10 (9,7%) | |
Lamotrigine | 7 (13.5%) | 28 (27.2%) | |
Valproat acid | 6 (11.5%) | 33 (32.%) | |
Seizure freedom > 1 month | 52 (96.2%) | 9 (8.7%) | |
Seizure freedom 10 days > month | 2 (3.8%) | 43 (41.7%) | |
Seizure freedom < 10 days | / | 51 (49.5%) |
Explanatory | Unstandardized | Standardized | t | p |
---|---|---|---|---|
Variables | Coefficient ± SE | Coefficient | ||
Drug responsivity | 13.369 ± 6.644 | 0.460 | 2.012 | 0.048 * |
Type of epilepsy | −3.122 ± 1.620 | −0.185 | −1.927 | 0.058 * |
Illness duration | −0.607 ± 0.199 | −0.303 | 3.048 | 0.003 * |
Seizures control | 1.034 ± 2.219 | 0.104 | 0.466 | 0.642 |
EEG findings | −1.239 ± 0.17 | −0.103 | −1.014 | 0.314 |
Categories | Explanatory Variables | B | SE | Wald | p | 95% CI |
---|---|---|---|---|---|---|
Anxiety | EEG findings | 0.716 | 0.366 | 3.826 | 0.05 | 0.99–4.912 |
Baseline | ||||||
Anxiety 12 | Drug responsivity | −5.169 | 1.991 | 6.738 | 0.009 | 0.000–0.282 |
Epilepsy duration | 0.126 | 0.051 | 6.064 | 0.014 | 0.798–0.975 | |
Type of epilepsy | 0.021 | 0.525 | 3.780 | 0.052 | 0.992–7.763 | |
Anxiety 18 | Drug responsivity | −5.131 | 1.906 | 7.250 | 0.007 | 0.00–0.248 |
Epilepsy duration | −0.139 | 9.053 | 6.980 | 0.008 | 0.785–0.965 | |
Type of epilepsy | 0.588 | 0.411 | 2.502 | 0.152 | 0.805–4.028 | |
EEG findings | −0.045 | 0.333 | 0.018 | 0.892 | 0.498–1.834 | |
Seizure control | −0.336 | 0.606 | 0.308 | 0.579 | 0.218–2.341 |
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Gavrilovic, A.; Gavrilovic, J.; Ilic Zivojinovic, J.; Jeličić, L.; Radovanovic, S.; Vesic, K. Influence of Epilepsy Characteristics on the Anxiety Occurrence. Brain Sci. 2024, 14, 858. https://doi.org/10.3390/brainsci14090858
Gavrilovic A, Gavrilovic J, Ilic Zivojinovic J, Jeličić L, Radovanovic S, Vesic K. Influence of Epilepsy Characteristics on the Anxiety Occurrence. Brain Sciences. 2024; 14(9):858. https://doi.org/10.3390/brainsci14090858
Chicago/Turabian StyleGavrilovic, Aleksandar, Jagoda Gavrilovic, Jelena Ilic Zivojinovic, Ljiljana Jeličić, Snezana Radovanovic, and Katarina Vesic. 2024. "Influence of Epilepsy Characteristics on the Anxiety Occurrence" Brain Sciences 14, no. 9: 858. https://doi.org/10.3390/brainsci14090858