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Open AccessArticle
Assessing the Impact of (Poly)phenol-Rich Foods on Cardiometabolic Risk in Postmenopausal Women: A Dietary Trial
by
Lorena Sánchez-Martínez
Lorena Sánchez-Martínez 1,2,
Rocío González-Barrio
Rocío González-Barrio 1,2,*,†,
Javier García-Alonso
Javier García-Alonso 1,2,
Pedro Mena
Pedro Mena 3,4 and
María-Jesús Periago
María-Jesús Periago 1,*,†
1
Department of Food Technology, Food Science and Nutrition, University of Murcia, CEIR Campus Mare Nostrum, Campus de Espinardo, 30100 Murcia, Spain
2
Biomedical Reserach Institute of Murcia (IMIB-Arrixaca-UMU), University Clinical Hospital “Virgen de la Arrixaca”, El Palmar, 30120 Murcia, Spain
3
Department of Food and Drug, University of Parma, Via Volturno 39, 43125 Parma, Italy
4
Microbiome Research Hub, University of Parma, Parco Area delle Scienze 11/A, 43124 Parma, Italy
*
Authors to whom correspondence should be addressed.
†
These authors contributed equally to this work.
Antioxidants 2024, 13(8), 973; https://doi.org/10.3390/antiox13080973 (registering DOI)
Submission received: 30 June 2024
/
Revised: 3 August 2024
/
Accepted: 7 August 2024
/
Published: 9 August 2024
Abstract
Menopause is a critical stage in a woman’s life in which cardiometabolic alterations appear, such as insulin resistance or a predisposition to visceral fat deposits, leading to an increased risk of cardiometabolic diseases (R-CMBs). New strategies to reduce the R-CMBs in postmenopausal women using natural compounds without adverse effects are desirable. In this sense, plant-based diets rich in fruits and vegetables could play a fundamental role due to the high content of bioactive compounds found in these diets, such as (poly)phenols, known for their antioxidant, anti-inflammatory and vasodilator properties. The aim of this research was to carry out a dietary trial to evaluate the effect of the daily intake of different (poly)phenol-rich foods (PP-rich foods) for 2 months on the modulation of the main cardiometabolic risk biomarkers of postmenopausal women. The results showed a slight improvement in blood pressure (BP), lipid profile and oxidative stress, endothelial function and inflammatory biomarkers. These findings suggest that daily consumption of PP-rich foods alleviated the R-CMBs of postmenopausal women by reducing the oxidative stress and, thus, the risk of cardiovascular events; however, the magnitude of the cardioprotective effect of (poly)phenols depends on inter-individual variability.
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MDPI and ACS Style
Sánchez-Martínez, L.; González-Barrio, R.; García-Alonso, J.; Mena, P.; Periago, M.-J.
Assessing the Impact of (Poly)phenol-Rich Foods on Cardiometabolic Risk in Postmenopausal Women: A Dietary Trial. Antioxidants 2024, 13, 973.
https://doi.org/10.3390/antiox13080973
AMA Style
Sánchez-Martínez L, González-Barrio R, García-Alonso J, Mena P, Periago M-J.
Assessing the Impact of (Poly)phenol-Rich Foods on Cardiometabolic Risk in Postmenopausal Women: A Dietary Trial. Antioxidants. 2024; 13(8):973.
https://doi.org/10.3390/antiox13080973
Chicago/Turabian Style
Sánchez-Martínez, Lorena, Rocío González-Barrio, Javier García-Alonso, Pedro Mena, and María-Jesús Periago.
2024. "Assessing the Impact of (Poly)phenol-Rich Foods on Cardiometabolic Risk in Postmenopausal Women: A Dietary Trial" Antioxidants 13, no. 8: 973.
https://doi.org/10.3390/antiox13080973
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