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Vaccines, Volume 10, Issue 5

May 2022 - 196 articles

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Cover Story: The SARS-CoV-2 pandemic is combated with a third vaccination. Considering initially different vaccination regimens, we addressed whether previous vaccinations influence the immune response to the booster. Healthcare workers that received either two doses of BNT162b2 or a priming dose of ChAdOx1-nCoV-19 followed by a BNT162b2 dose were recruited and vaccinated with a third dose of BNT162b2. Initially significant differences in the antibody concentrations rapidly aligned. The same was the case for initially age-dependent differences in the anti-S concentrations. The measured T cell responses did not show any differences depending on the vaccination regimen. The results imply that a third vaccination dose elicits comparable immune responses in differentially immunized individuals, which is of major importance for healthcare policy makers. View this paper

Articles (196)

  • Article
  • Open Access
4 Citations
3,983 Views
15 Pages

Impact of the Threat of COVID-19 Infections on the Perceived Risk to HPV Vaccination

  • Yumi Shimizu,
  • Kei Hirai,
  • Yutaka Ueda,
  • Asami Yagi and
  • Fumio Ohtake

Vaccination rates for human papillomavirus (HPV) in Japan are significantly lower than other countries, and Japanese people are reluctant to be vaccinated. Repeated daily reports of COVID-19 infections and restrictions have made people more health co...

  • Article
  • Open Access
2 Citations
3,224 Views
15 Pages

Preclinical Efficacy of a Capsid Virus-like Particle-Based Vaccine Targeting IL-1β for Treatment of Allergic Contact Dermatitis

  • Louise Goksøyr,
  • Anders B. Funch,
  • Anna K. Okholm,
  • Thor G. Theander,
  • Willem Adriaan de Jongh,
  • Charlotte M. Bonefeld and
  • Adam F. Sander

Hypersensitivity to a contact allergen is one of the most abundant forms of inflammatory skin disease. Today, more than 20% of the general population are sensitized to one or more contact allergens, making this disease an important healthcare issue,...

  • Article
  • Open Access
2 Citations
2,918 Views
14 Pages

Reanalysis of a Randomized Controlled Trial on Promoting Influenza Vaccination in General Practice Waiting Rooms: A Zelen Design

  • Christophe Berkhout,
  • Jeroen De Man,
  • Claire Collins,
  • Amy Willefert-Bouche,
  • Suzanna Zgorska-Maynard Moussa,
  • Margot Badelon,
  • Lieve Peremans and
  • Paul Van Royen

In 2014–2015, we conducted a randomized controlled trial (RCT) assessing the effect of an advertising campaign for influenza vaccination using posters and pamphlets in general practitioner (GP) waiting rooms. No effect of the intervention could...

  • Review
  • Open Access
8 Citations
4,651 Views
39 Pages

Recombinant BCG to Enhance Its Immunomodulatory Activities

  • Magdalena Kowalewicz-Kulbat and
  • Camille Locht

The bacillus Calmette–Guérin (BCG) is an attenuated Mycobacterium bovis derivative that has been widely used as a live vaccine against tuberculosis for a century. In addition to its use as a tuberculosis vaccine, BCG has also been found...

  • Article
  • Open Access
28 Citations
4,012 Views
13 Pages

Therapeutic Effect of Subunit Vaccine AEC/BC02 on Mycobacterium tuberculosis Post-Chemotherapy Relapse Using a Latent Infection Murine Model

  • Jinbiao Lu,
  • Xiaonan Guo,
  • Chunhua Wang,
  • Weixin Du,
  • Xiaobing Shen,
  • Cheng Su,
  • Yongge Wu and
  • Miao Xu

Tuberculosis (TB), caused by the human pathogen Mycobacterium tuberculosis (Mtb), is an infectious disease that presents a major threat to human health. Bacillus Calmette-Guérin (BCG), the only licensed TB vaccine, is ineffective against laten...

  • Article
  • Open Access
28 Citations
4,883 Views
16 Pages

Background. The high prevalence of HPV infection among Kazakhstani women and the absence of an HPV vaccination program are directly reflected in increasing rates of cervical cancer incidence and mortality. Kazakhstan made its first attempt at introdu...

  • Case Report
  • Open Access
7 Citations
4,173 Views
7 Pages

A 30-year-old male diagnosed three years previously with reversible cerebral vasoconstriction syndrome (RCVS) presented to the department of neurology with an accumulation of attacks mimicking previous RCVS attacks and fulfilling the diagnostic crite...

  • Protocol
  • Open Access
3 Citations
3,117 Views
8 Pages

Vaccines against COVID-19 approved for use in the EU/EEA have been shown to be highly effective against wild-type SARS-CoV-2. However, their effectiveness against new variants may be reduced. This study aims to evaluate the effectiveness of vaccines...

  • Brief Report
  • Open Access
19 Citations
4,203 Views
9 Pages

Out-of-Season Influenza during a COVID-19 Void in the State of Rio de Janeiro, Brazil: Temperature Matters

  • Rohini Nott,
  • Trevon L. Fuller,
  • Patrícia Brasil and
  • Karin Nielsen-Saines

An out-of-season H3N2 type A influenza epidemic occurred in the State of Rio de Janeiro, Brazil during October–November 2021, in between the Delta and Omicron SARS-CoV-2 surges, which occurred in July–October 2021 and January–April...

  • Article
  • Open Access
16 Citations
4,086 Views
13 Pages

Iraqi Parents’ Knowledge, Attitudes, and Practices towards Vaccinating Their Children: A Cross-Sectional Study

  • Walid Al-Qerem,
  • Anan Jarab,
  • Alaa Hammad,
  • Fawaz Alasmari,
  • Jonathan Ling,
  • Alaa Hussein Alsajri,
  • Shadan Waleed Al-Hishma and
  • Shrouq R. Abu Heshmeh

The focus of coronavirus disease 2019 (COVID-19) vaccination campaigns has been the adult population, particularly the elderly and those with chronic diseases. However, COVID-19 can also affect children and adolescents. Furthermore, targeting this po...

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