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Article

Gestational Diabetes and Preterm Birth: What Do We Know? Our Experience and Mini-Review of the Literature

by
Agnesa Preda
1,†,
Dominic-Gabriel Iliescu
1,2,
Alexandru Comănescu
1,2,
George-Lucian Zorilă
1,2,
Ionela Mihaela Vladu
3,4,†,
Mircea-Cătălin Forțofoiu
5,6,*,
Tiberiu Stefaniță Țenea-Cojan
7,8,*,
Silviu-Daniel Preda
9,
Ileana-Diana Diaconu
10,11,†,
Eugen Moța
11,
Ioan-Ovidiu Gheorghe
11,* and
Maria Moța
11
1
Department of Obstetrics and Gynecology, University Emergency County Hospital Craiova, 200642 Craiova, Romania
2
Department of Obstetrics and Gynecology, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania
3
Department of Diabetes, Nutrition and Metabolic Diseases, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
4
Department of Diabetes, Nutrition and Metabolic Diseases, University Emergency County Hospital Craiova, 200642 Craiova, Romania
5
Department of Medical Semiology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
6
Department of Internal Medicine 2, “Philanthropy” Clinical Municipal Hospital of Craiova, 200143 Craiova, Romania
7
Department of General Surgery, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
8
Department of General Surgery, C.F. Clinical Hospital, 200374 Craiova, Romania
9
Department of Surgery, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
10
Department of Pediatric Pneumology, “Marius Nasta” National Institute of Pneumophtisiology, 050159 Bucharest, Romania
11
Doctoral School, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania
*
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
J. Clin. Med. 2023, 12(14), 4572; https://doi.org/10.3390/jcm12144572
Submission received: 9 June 2023 / Revised: 28 June 2023 / Accepted: 6 July 2023 / Published: 9 July 2023
(This article belongs to the Special Issue Clinical Management of Pregnancy-Related Complications)

Abstract

Background: Gestational diabetes mellitus (GDM) is a form of diabetes that develops during pregnancy. The incidence of GDM has been on the rise in tandem with the increasing prevalence of obesity worldwide. We focused on the study of what causes premature births and if there are methods to prevent these events that can result in long-term complications. Methods: This study was a prospective, non-interventional study that lasted for 4 years from December 2018 to December 2022. From the group of women enrolled in the study, we selected and analyzed the characteristics of women who gave birth prematurely. Additionally, we performed a systematic review examining the association between GDM and the frequency of adverse pregnancy outcomes. Results: In total, 78% underwent an emergency caesarean and had polyhydramnios. The results indicate that women who had a preterm delivery had a significantly higher maternal age compared to those who had a term delivery (p < 0.001). Conversely, there was no significant difference in preconception BMI between the two groups (p = 0.12). Conclusions: In terms of the understanding of GDM and preterm birth, several gaps in our knowledge remain. The association between GDM and preterm birth is likely multifactorial, involving various maternal factors.
Keywords: gestational diabetes mellitus; preterm birth; maternal factors; pregnancy gestational diabetes mellitus; preterm birth; maternal factors; pregnancy

Share and Cite

MDPI and ACS Style

Preda, A.; Iliescu, D.-G.; Comănescu, A.; Zorilă, G.-L.; Vladu, I.M.; Forțofoiu, M.-C.; Țenea-Cojan, T.S.; Preda, S.-D.; Diaconu, I.-D.; Moța, E.; et al. Gestational Diabetes and Preterm Birth: What Do We Know? Our Experience and Mini-Review of the Literature. J. Clin. Med. 2023, 12, 4572. https://doi.org/10.3390/jcm12144572

AMA Style

Preda A, Iliescu D-G, Comănescu A, Zorilă G-L, Vladu IM, Forțofoiu M-C, Țenea-Cojan TS, Preda S-D, Diaconu I-D, Moța E, et al. Gestational Diabetes and Preterm Birth: What Do We Know? Our Experience and Mini-Review of the Literature. Journal of Clinical Medicine. 2023; 12(14):4572. https://doi.org/10.3390/jcm12144572

Chicago/Turabian Style

Preda, Agnesa, Dominic-Gabriel Iliescu, Alexandru Comănescu, George-Lucian Zorilă, Ionela Mihaela Vladu, Mircea-Cătălin Forțofoiu, Tiberiu Stefaniță Țenea-Cojan, Silviu-Daniel Preda, Ileana-Diana Diaconu, Eugen Moța, and et al. 2023. "Gestational Diabetes and Preterm Birth: What Do We Know? Our Experience and Mini-Review of the Literature" Journal of Clinical Medicine 12, no. 14: 4572. https://doi.org/10.3390/jcm12144572

APA Style

Preda, A., Iliescu, D.-G., Comănescu, A., Zorilă, G.-L., Vladu, I. M., Forțofoiu, M.-C., Țenea-Cojan, T. S., Preda, S.-D., Diaconu, I.-D., Moța, E., Gheorghe, I.-O., & Moța, M. (2023). Gestational Diabetes and Preterm Birth: What Do We Know? Our Experience and Mini-Review of the Literature. Journal of Clinical Medicine, 12(14), 4572. https://doi.org/10.3390/jcm12144572

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