Bile Acid Composition and Transcriptome Analysis of the Liver and Small Intestine in Different Species
Abstract
:1. Introduction
2. Materials and Methods
2.1. Ethics Statement
2.2. Experimental Animals and Samples
2.3. Metabolome Processing and Analyses
2.4. RNA Extraction and Sequencing
2.5. Transcriptome Analysis
3. Results
3.1. Analysis of the Bile Acid Composition of Different Species
3.2. Differentiated BA Metabolites and KEGG Pathway
3.3. Analysis of the Transcriptome of the Liver and Small Intestine among Different Species
3.4. Differentially Expressed Genes in Two Tissues among Six Species
3.5. Correlation Analysis between Gene Expression and BA Content
4. Discussion
5. Limitations of the Study
6. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
References
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Qi, D.; Zheng, T.; Yang, M.; Huang, Z.; Wang, T.; Wang, Q.; Chen, B. Bile Acid Composition and Transcriptome Analysis of the Liver and Small Intestine in Different Species. Metabolites 2024, 14, 451. https://doi.org/10.3390/metabo14080451
Qi D, Zheng T, Yang M, Huang Z, Wang T, Wang Q, Chen B. Bile Acid Composition and Transcriptome Analysis of the Liver and Small Intestine in Different Species. Metabolites. 2024; 14(8):451. https://doi.org/10.3390/metabo14080451
Chicago/Turabian StyleQi, Dongming, Tingting Zheng, Maosen Yang, Zhiying Huang, Tao Wang, Qiang Wang, and Binlong Chen. 2024. "Bile Acid Composition and Transcriptome Analysis of the Liver and Small Intestine in Different Species" Metabolites 14, no. 8: 451. https://doi.org/10.3390/metabo14080451