Poly(N-isopropylacrylamide-co-2-((diethylamino)methyl)-4-formyl-6-methoxyphenyl acrylate) Environmental Functional Copolymers: Synthesis, Characterizations, and Grafting with Amino Acids
Abstract
:1. Introduction
2. Material and Methods
2.1. Materials
2.2. Instrumentations and Measurements
2.3. Synthesis of 2-((diethylamino)methyl)-4-formyl-6-methoxyphenyl acrylate (II) (DEMAVA)
2.3.1. Step 1: Preparation of 3-((diethylamino)methyl)-4-hydroxy-5-methoxy-benzaldehyde) (I)
2.3.2. Step 2: Preparation of 2-((diethylamino)methyl)-4-formyl-6-methoxyphenyl acrylate) (II) (DEAMVA)
2.4. Preparation of Poly (NIPAAm-co-DEAMVA) with 5, 10 and 15 mol % of DEAMVA (IIIa–c)
2.5. Synthesis of Grafted 15 mol % Poly (NIPAAm-co-DEAMVA) with Tryptophan and Tyrosine (IV–V)
2.6. Synthesis of Grafted 15 mol % Poly (NIPAAm-co-DEAMVA)-g-tyrosine as a Function of Time
3. Results and Discussion
3.1. Synthesis of Monomer, Copolymers and Grafted Copolymers
3.1.1. Step 1: Is the formation of (3-[(diethylamino) methyl)-4-hydroxy-5-methoxy-benzaldehyde) (I)
3.2.2. Step 2: Is the formation of 2-[(diethylamino)methyl]-4-formyl-6-methoxyphenyl acrylate (DEMAVA) (II)
3.2. Polymer Characterization
Molecular Weight
3.3. Study of the Phase Separation of Poly (NIPAAm-Co-DEAMVA) and Grafted Polymers
3.4. Determination of the Conversion of poly (NIPAAm-Co-DEAMVA) to Poly (NIPAAm-Co-DEAMVA)-g-Tryptophan
3.5. The Thermal Properties
3.6. Morphological Studies
4. Conclusions
Funding
Acknowledgments
Conflicts of Interest
References
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Polymer | Yield (%) | 1H NMR DEAMVA (mol %) | Conversion (%) | Mn a (g/mol) 104 | Ð b | Tgc (°C) | Tc d (°C) | ||
---|---|---|---|---|---|---|---|---|---|
pH 7 | pH 1.68 | pH 12.46 | |||||||
IIIa | 83 | 3.55 | - | 15,340 | 1.98 | 122 | 35 | 43 | - |
IIIb | 82 | 7.26 | - | 12,260 | 2.27 | 127 | 38.5 | 52 | - |
IIIc | 76 | 11.36 | - | 10,580 | 2.46 | 137 | 44 | 60 | - |
IV | 80 | - | 84 | 7750 | 1.87 | 136 | 50 | 44 | - |
V | 81 | - | 79 | 10,270 | 2.12 | 133 | 42 | 42 | - |
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Abdelaty, M.S.A. Poly(N-isopropylacrylamide-co-2-((diethylamino)methyl)-4-formyl-6-methoxyphenyl acrylate) Environmental Functional Copolymers: Synthesis, Characterizations, and Grafting with Amino Acids. Biomolecules 2018, 8, 138. https://doi.org/10.3390/biom8040138
Abdelaty MSA. Poly(N-isopropylacrylamide-co-2-((diethylamino)methyl)-4-formyl-6-methoxyphenyl acrylate) Environmental Functional Copolymers: Synthesis, Characterizations, and Grafting with Amino Acids. Biomolecules. 2018; 8(4):138. https://doi.org/10.3390/biom8040138
Chicago/Turabian StyleAbdelaty, Momen S. A. 2018. "Poly(N-isopropylacrylamide-co-2-((diethylamino)methyl)-4-formyl-6-methoxyphenyl acrylate) Environmental Functional Copolymers: Synthesis, Characterizations, and Grafting with Amino Acids" Biomolecules 8, no. 4: 138. https://doi.org/10.3390/biom8040138