Mechanisms of Organophosphate Toxicity and the Role of Acetylcholinesterase Inhibition
Abstract
:1. Introduction
2. Cholinergic Mechanisms of OP Toxicity
2.1. Depression of Respiration
2.2. Induction of Seizures and Status Epilepticus
2.3. Seizures and Status Epilepticus as the Primary Mediators of OP Neurotoxicity
3. Mechanisms of OP Toxicity That Do Not Depend on Status Epilepticus or AChE Inhibition
4. Conclusions
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
Footnotes
References
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Aroniadou-Anderjaska, V.; Figueiredo, T.H.; de Araujo Furtado, M.; Pidoplichko, V.I.; Braga, M.F.M. Mechanisms of Organophosphate Toxicity and the Role of Acetylcholinesterase Inhibition. Toxics 2023, 11, 866. https://doi.org/10.3390/toxics11100866
Aroniadou-Anderjaska V, Figueiredo TH, de Araujo Furtado M, Pidoplichko VI, Braga MFM. Mechanisms of Organophosphate Toxicity and the Role of Acetylcholinesterase Inhibition. Toxics. 2023; 11(10):866. https://doi.org/10.3390/toxics11100866
Chicago/Turabian StyleAroniadou-Anderjaska, Vassiliki, Taiza H. Figueiredo, Marcio de Araujo Furtado, Volodymyr I. Pidoplichko, and Maria F. M. Braga. 2023. "Mechanisms of Organophosphate Toxicity and the Role of Acetylcholinesterase Inhibition" Toxics 11, no. 10: 866. https://doi.org/10.3390/toxics11100866
APA StyleAroniadou-Anderjaska, V., Figueiredo, T. H., de Araujo Furtado, M., Pidoplichko, V. I., & Braga, M. F. M. (2023). Mechanisms of Organophosphate Toxicity and the Role of Acetylcholinesterase Inhibition. Toxics, 11(10), 866. https://doi.org/10.3390/toxics11100866