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Bioengineering, Volume 3, Issue 1

2016 March - 10 articles

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Articles (10)

  • Article
  • Open Access
10 Citations
7,393 Views
16 Pages

Enterohemorrhagic Escherichia coli (EHEC) are responsible for large outbreaks of hemorrhagic colitis, which can progress to life-threatening hemolytic uremic syndrome (HUS) due to the release of Shiga-like toxins (Stx). The presence of a functional n...

  • Review
  • Open Access
45 Citations
11,562 Views
10 Pages

Co-utilization of carbon sources in microbes is an important topic in metabolic engineering research. It is not only a way to reduce microbial production costs but also an attempt for either improving the yields of target products or decreasing the f...

  • Article
  • Open Access
30 Citations
16,458 Views
24 Pages

DNA and RNA Extraction and Quantitative Real-Time PCR-Based Assays for Biogas Biocenoses in an Interlaboratory Comparison

  • Michael Lebuhn,
  • Jaqueline Derenkó,
  • Antje Rademacher,
  • Susanne Helbig,
  • Bernhard Munk,
  • Alexander Pechtl,
  • Yvonne Stolze,
  • Steffen Prowe,
  • Wolfgang H. Schwarz and
  • Michael Klocke
  • + 2 authors

Five institutional partners participated in an interlaboratory comparison of nucleic acid extraction, RNA preservation and quantitative Real-Time PCR (qPCR) based assays for biogas biocenoses derived from different grass silage digesting laboratory a...

  • Article
  • Open Access
41 Citations
18,151 Views
29 Pages

Metabolic Control in Mammalian Fed-Batch Cell Cultures for Reduced Lactic Acid Accumulation and Improved Process Robustness

  • Viktor Konakovsky,
  • Christoph Clemens,
  • Markus Michael Müller,
  • Jan Bechmann,
  • Martina Berger,
  • Stefan Schlatter and
  • Christoph Herwig

Biomass and cell-specific metabolic rates usually change dynamically over time, making the “feed according to need” strategy difficult to realize in a commercial fed-batch process. We here demonstrate a novel feeding strategy which is designed to hol...

  • Review
  • Open Access
11 Citations
8,108 Views
13 Pages

Controlling Arteriogenesis and Mast Cells Are Central to Bioengineering Solutions for Critical Bone Defect Repair Using Allografts

  • Ben Antebi,
  • Longze Zhang,
  • Dmitriy Sheyn,
  • Gadi Pelled,
  • Xinping Zhang,
  • Zulma Gazit,
  • Edward M. Schwarz and
  • Dan Gazit

Although most fractures heal, critical defects in bone fail due to aberrant differentiation of mesenchymal stem cells towards fibrosis rather than osteogenesis. While conventional bioengineering solutions to this problem have focused on enhancing ang...

  • Article
  • Open Access
7 Citations
7,568 Views
14 Pages

Transient Mechanical Response of Lung Airway Tissue during Mechanical Ventilation

  • Israr Bin Muhammad Ibrahim,
  • Parya Aghasafari and
  • Ramana M. Pidaparti

Patients with acute lung injury, airway and other pulmonary diseases often require Mechanical Ventilation (MV). Knowledge of the stress/strain environment in lung airway tissues is very important in order to avoid lung injuries for patients undergoin...

  • Review
  • Open Access
20 Citations
19,397 Views
32 Pages

Metabolic engineering of various industrial microorganisms to produce chemicals, fuels, and drugs has raised interest since it is environmentally friendly, sustainable, and independent of nonrenewable resources. However, microbial metabolism is so co...

  • Article
  • Open Access
15 Citations
9,202 Views
15 Pages

Rebalancing Redox to Improve Biobutanol Production by Clostridium tyrobutyricum

  • Chao Ma,
  • Jianfa Ou,
  • Ningning Xu,
  • Janna L. Fierst,
  • Shang-Tian Yang and
  • Xiaoguang Liu

Biobutanol is a sustainable green biofuel that can substitute for gasoline. Carbon flux has been redistributed in Clostridium tyrobutyricum via metabolic cell engineering to produce biobutanol. However, the lack of reducing power hampered the further...

  • Article
  • Open Access
57 Citations
7,689 Views
14 Pages

Sustained Release of Antibacterial Agents from Doped Halloysite Nanotubes

  • Shraddha Patel,
  • Uday Jammalamadaka,
  • Lin Sun,
  • Karthik Tappa and
  • David K. Mills

The use of nanomaterials for improving drug delivery methods has been shown to be advantageous technically and viable economically. This study employed the use of halloysite nanotubes (HNTs) as nanocontainers, as well as enhancers of structural integ...

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Bioengineering - ISSN 2306-5354