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Bioengineering, Volume 8, Issue 10

2021 October - 17 articles

Cover Story: The generation of a good-quality digital anatomical model of the heart is a complex task. Its 3D representation, however, has the potential to provide detailed spatial information concerning the heart’s structure, also offering new opportunities if combined with additive manufacturing. In this work, we illustrate the difficulties that may be encountered in the workflow from a stack of computed tomography (CT) to the handheld printed heart model, which also considers real wall thickness variability. Stereolithography printing technology is exploited, and the accuracy of the result evaluated. View this paper
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Articles (17)

  • Review
  • Open Access
62 Citations
6,511 Views
19 Pages

Metal Oxide Nanoparticles and Nanotubes: Ultrasmall Nanostructures to Engineer Antibacterial and Improved Dental Adhesives and Composites

  • Abdulrahman A. Balhaddad,
  • Isadora M. Garcia,
  • Lamia Mokeem,
  • Rashed Alsahafi,
  • Fabrício Mezzomo Collares and
  • Mary Anne Sampaio de Melo

Advances in nanotechnology have unlocked exclusive and relevant capabilities that are being applied to develop new dental restorative materials. Metal oxide nanoparticles and nanotubes perform functions relevant to a range of dental purposes beyond t...

  • Review
  • Open Access
41 Citations
6,626 Views
21 Pages

Translational Application of 3D Bioprinting for Cartilage Tissue Engineering

  • Sophie McGivern,
  • Halima Boutouil,
  • Ghayadah Al-Kharusi,
  • Suzanne Little,
  • Nicholas J. Dunne and
  • Tanya J. Levingstone

Cartilage is an avascular tissue with extremely limited self-regeneration capabilities. At present, there are no existing treatments that effectively stop the deterioration of cartilage or reverse its effects; current treatments merely relieve its sy...

  • Article
  • Open Access
13 Citations
2,971 Views
15 Pages

Viscoelastic Characterization of Parasagittal Bridging Veins and Implications for Traumatic Brain Injury: A Pilot Study

  • Silvia García-Vilana,
  • David Sánchez-Molina,
  • Jordi Llumà,
  • Ignasi Galtés,
  • Juan Velázquez-Ameijide,
  • M. Carmen Rebollo-Soria and
  • Carlos Arregui-Dalmases

Many previous studies on the mechanical properties of Parasagittal Bridging Veins (PSBVs) found that strain rate had a significant effect on some mechanical properties, but did not extensively study the viscoelastic effects, which are difficult to de...

  • Article
  • Open Access
17 Citations
5,878 Views
14 Pages

Hemodynamic Investigation of the Effectiveness of a Two Overlapping Flow Diverter Configuration for Cerebral Aneurysm Treatment

  • Yuya Uchiyama,
  • Soichiro Fujimura,
  • Hiroyuki Takao,
  • Takashi Suzuki,
  • Motoharu Hayakawa,
  • Toshihiro Ishibashi,
  • Kostadin Karagiozov,
  • Koji Fukudome,
  • Yuichi Murayama and
  • Makoto Yamamoto

Flow diverters (FDs) are widely employed as endovascular treatment devices for large or wide-neck cerebral aneurysms. Occasionally, overlapped FDs are deployed to enhance the flow diversion effect. In this study, we investigated the hemodynamics of o...

  • Article
  • Open Access
2 Citations
3,537 Views
13 Pages

The enzyme alkaline phosphatase (ALP) is gaining interest because it exerts bioactive properties and may be a potentially important therapeutic agent for many disorders and diseases. Microalgae are considered an important novel source for the product...

  • Article
  • Open Access
29 Citations
4,602 Views
13 Pages

Biotechnological Conversion of Grape Pomace to Poly(3-hydroxybutyrate) by Moderately Thermophilic Bacterium Tepidimonas taiwanensis

  • Xenie Kourilova,
  • Iva Pernicova,
  • Michaela Vidlakova,
  • Roman Krejcirik,
  • Katerina Mrazova,
  • Kamila Hrubanova,
  • Vladislav Krzyzanek,
  • Jana Nebesarova and
  • Stanislav Obruca

Polyhydroxyalkanoates (PHA) are microbial polyesters that have recently come to the forefront of interest due to their biodegradability and production from renewable sources. A potential increase in competitiveness of PHA production process comes wit...

  • Article
  • Open Access
5 Citations
3,257 Views
17 Pages

Echogenic Advantages of Ferrogels Filled with Magnetic Sub-Microparticles

  • Olga A. Dinislamova,
  • Antonina V. Bugayova,
  • Tatyana F. Shklyar,
  • Alexander P. Safronov and
  • Felix A. Blyakhman

Ultrasonic imaging of ferrogels (FGs) filled with magnetic nanoparticles does not reflect the inner structure of FGs due to the small size of particles. To determine whether larger particle size would improve the acoustic properties of FGs, biocompat...

  • Review
  • Open Access
12 Citations
6,489 Views
31 Pages

Bioengineering of Extracellular Vesicles: Exosome-Based Next-Generation Therapeutic Strategy in Cancer

  • Priyanka Saha,
  • Suchisnigdha Datta,
  • Sukanya Ghosh,
  • Anurima Samanta,
  • Paramita Ghosh and
  • Dona Sinha

Extracellular nano vesicles and exosomes hold compelling evidence in intercellular communication. Exosomal intracellular signal transduction is mediated by the transfer of cargo proteins, lipids, micro (mi)RNAs, long noncoding (lnc)RNAs, small interf...

  • Article
  • Open Access
26 Citations
4,804 Views
13 Pages

Extracting Features from Poincaré Plots to Distinguish Congestive Heart Failure Patients According to NYHA Classes

  • Giovanni D’Addio,
  • Leandro Donisi,
  • Giuseppe Cesarelli,
  • Federica Amitrano,
  • Armando Coccia,
  • Maria Teresa La Rovere and
  • Carlo Ricciardi

Heart-rate variability has proved a valid tool in prognosis definition of patients with congestive heart failure (CHF). Previous research has documented Poincaré plot analysis as a valuable approach to study heart-rate variability performance among d...

  • Article
  • Open Access
3 Citations
4,041 Views
14 Pages

Due to their osteoconductive properties, allogenic bone screws made of human cortical bone have advantages regarding rehabilitation compared to other materials such as stainless steel or titanium. Since conventional screw drives like hexagonal or hex...

  • Review
  • Open Access
53 Citations
9,325 Views
28 Pages

With population aging and increased life expectancy, an increasing number of people are facing musculoskeletal health problems that necessitate therapeutic intervention at defect sites. Bone tissue engineering (BTE) has become a promising approach fo...

  • Review
  • Open Access
59 Citations
8,056 Views
23 Pages

Magnetic iron oxide nanoparticles (MNPs) have been developed and applied for a broad range of biomedical applications, such as diagnostic imaging, magnetic fluid hyperthermia, targeted drug delivery, gene therapy and tissue repair. As one key element...

  • Review
  • Open Access
8 Citations
8,408 Views
42 Pages

Biofabrication of Artificial Stem Cell Niches in the Anterior Ocular Segment

  • Veronica Hidalgo-Alvarez,
  • Hala S. Dhowre,
  • Olivia A. Kingston,
  • Carl M. Sheridan and
  • Hannah J. Levis

The anterior segment of the eye is a complex set of structures that collectively act to maintain the integrity of the globe and direct light towards the posteriorly located retina. The eye is exposed to numerous physical and environmental insults suc...

  • Review
  • Open Access
21 Citations
7,862 Views
13 Pages

Recent Advancements in 3D Printing and Bioprinting Methods for Cardiovascular Tissue Engineering

  • Foteini K. Kozaniti,
  • Despoina Nektaria Metsiou,
  • Aikaterini E. Manara,
  • George Athanassiou and
  • Despina D. Deligianni

Recent decades have seen a plethora of regenerating new tissues in order to treat a multitude of cardiovascular diseases. Autografts, xenografts and bioengineered extracellular matrices have been employed in this endeavor. However, current limitation...

  • Article
  • Open Access
2 Citations
3,975 Views
10 Pages

Human Peripheral Nerve-Derived Pluripotent Cells Can Be Stimulated by In Vitro Bone Morphogenetic Protein-2

  • Renyi Sun,
  • Tanghong Jia,
  • Bradley Dart,
  • Sunaina Shrestha,
  • Morgan Bretches,
  • Michael H. Heggeness and
  • Shang-You Yang

We have recently identified a population of cells within the peripheral nerves of adult rodent animals (mice and rats) that can respond to Bone Morphogenetic Protein-2 (BMP-2) exposure or physical injury to rapidly proliferate. More importantly, thes...

  • Article
  • Open Access
22 Citations
5,394 Views
16 Pages

In Situ Visualization for 3D Ultrasound-Guided Interventions with Augmented Reality Headset

  • Nadia Cattari,
  • Sara Condino,
  • Fabrizio Cutolo,
  • Mauro Ferrari and
  • Vincenzo Ferrari

Augmented Reality (AR) headsets have become the most ergonomic and efficient visualization devices to support complex manual tasks performed under direct vision. Their ability to provide hands-free interaction with the augmented scene makes them perf...

  • Article
  • Open Access
21 Citations
6,680 Views
15 Pages

Medical images do not provide a natural visualization of 3D anatomical structures, while 3D digital models are able to solve this problem. Interesting applications based on these models can be found in the cardiovascular field. The generation of a go...

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Bioengineering - ISSN 2306-5354