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Veterinary Sciences, Volume 6, Issue 2

2019 June - 24 articles

Cover Story: Cytokines are produced by both cancer cells and the tumour microenvironment, and play an important role in many processes underlining cancer growth and progression, including but not limited to angiogenesis, cell proliferation, and cell adhesion. Using a comparative approach, this review explores the pro- and occasionally anti-tumourigenic potential of cytokines in those canine tumours that are considered excellent translational models: lymphoma, osteosarcoma, mammary gland tumours, and melanoma. In veterinary oncology, cytokines may thus provide a reliable contribution in setting up new screening tests, defining the prognostic signature of selected cancers and designing new therapeutic strategies. View this paper
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Articles (24)

  • Article
  • Open Access
6 Citations
5,140 Views
9 Pages

Mycobacterium avium subsp. paratuberculosis ELISA Responses in Milk Samples from Vaccinated and Nonvaccinated Dairy Goat Herds in The Netherlands

  • Saskia Luttikholt,
  • Karianne Lievaart-Peterson,
  • Maaike Gonggrijp,
  • Marian Aalberts,
  • Gerdien van Schaik and
  • Piet Vellema

The aims of our study were to calculate the most appropriate cut-off value for milk samples in a serum-validated Mycobacterium avium subsp. paratuberculosis (MAP) ELISA and to analyze MAP ELISA responses in milk samples from vaccinated and nonvaccina...

  • Communication
  • Open Access
47 Citations
6,582 Views
9 Pages

This survey was conducted to investigate the contamination by multiple mycotoxins, aflatoxins (AFB1, AFB2, AFG1, and AFG2), ochratoxin A (OTA), and zearalenone (ZEA) in 61 samples of maize and 17 commercial animal feed samples, and of aflatoxin M1 (A...

  • Case Report
  • Open Access
4 Citations
6,650 Views
9 Pages

A twelve-year-old male castrated Chihuahua with a severe, microcytic, hypochromic, and nonregenerative direct antiglobulin test positive anemia characterized by marked spherocytosis was referred to the veterinary hospital. Abdominal ultrasound reveal...

  • Case Report
  • Open Access
28 Citations
6,325 Views
6 Pages

Characterisation of the First Bovine Parainfluenza Virus 3 Isolate Detected in Cattle in Turkey

  • Harun Albayrak,
  • Zafer Yazici,
  • Emre Ozan,
  • Cuneyt Tamer,
  • Ahmed Abd El Wahed,
  • Stefanie Wehner,
  • Kristina Ulrich and
  • Manfred Weidmann

A respiratory disease outbreak on a cattle farm in northern Turkey produced respiratory tract symptoms and severe pneumonia symptoms in 20 calves. Eight calves died, and a lung specimen from one carcass was analysed for bacteria and for viruses of th...

  • Article
  • Open Access
20 Citations
6,143 Views
19 Pages

A prior study in bovine mammary (MACT) cells indicated that long-chain fatty acids (LCFA) C16:0 and C18:0, but not unsaturated LCFA, control transcription of milk fat-related genes partly via the activation of peroxisome proliferator-activated recept...

  • Communication
  • Open Access
22 Citations
7,457 Views
8 Pages

Canine mast cell tumours (MCTs) present a wide variety of challenging clinical behaviours in terms of predicting the prognosis and choosing appropriate treatment. This study investigated the frequency, risk, and prognostic factors of MCTs in dogs adm...

  • Article
  • Open Access
3 Citations
5,523 Views
17 Pages

2,4-Thiazolidinedione in Well-Fed Lactating Dairy Goats: II. Response to Intra-Mammary Infection

  • Fernanda Rosa,
  • Misagh Moridi,
  • Johan S. Osorio,
  • Jayant Lohakare,
  • Erminio Trevisi,
  • Shelby Filley,
  • Charles Estill and
  • Massimo Bionaz

In a prior experiment, treatment of goats with the putative PPARγ agonist 2,4-thiazolidinedione (2,4-TZD) ameliorated the response to intramammary infection without evidence of PPARγ activation. The lack of PPARγ activation was poss...

  • Case Report
  • Open Access
3 Citations
5,680 Views
6 Pages

A seven-year-old spayed female Labrador retriever presented for necropsy following an acute history of thrombocytopenia, anemia, leukocytosis and abdominal effusion. A 2 × 3 × 10 cm, cylindrical to tubular, mottled red-to-tan mass extende...

  • Brief Report
  • Open Access
4,402 Views
6 Pages

Recent reports suggest that antibiotic therapy may either reduce or enhance the immune response to various porcine vaccines. Based upon these findings, we asked if antibiotic therapy alters immune cell populations, as measured by flow cytometry and/o...

  • Feature Paper
  • Article
  • Open Access
3 Citations
6,319 Views
11 Pages

Mortality Patterns in a Commercial Wean-To Finish Swine Production System

  • Samantha Mehling,
  • Alexandra Henao-Diaz,
  • Jeremy Maurer,
  • Ed Kluber,
  • Rachel Stika,
  • Christopher Rademacher,
  • Jeff Zimmerman,
  • Luis Giménez-Lirola,
  • Chong Wang and
  • David Baum
  • + 6 authors

Modern commercial pig production is a complex process that requires successful producers to understand and resolve factors associated with perturbations in production. One important perturbation is inventory loss due to mortality. In this study, data...

  • Review
  • Open Access
69 Citations
17,567 Views
19 Pages

Risk Factors for Development of Canine and Human Osteosarcoma: A Comparative Review

  • Kelly M. Makielski,
  • Lauren J. Mills,
  • Aaron L. Sarver,
  • Michael S. Henson,
  • Logan G. Spector,
  • Shruthi Naik and
  • Jaime F. Modiano

Osteosarcoma is the most common primary tumor of bone. Osteosarcomas are rare in humans, but occur more commonly in dogs. A comparative approach to studying osteosarcoma has highlighted many clinical and biologic aspects of the disease that are simil...

  • Feature Paper
  • Article
  • Open Access
6 Citations
6,123 Views
10 Pages

Novel Amphiphilic Cyclobutene and Cyclobutane cis-C18 Fatty Acid Derivatives Inhibit Mycobacterium avium subsp. paratuberculosis Growth

  • Denise K. Zinniel,
  • Wantanee Sittiwong,
  • Darrell D. Marshall,
  • Govardhan Rathnaiah,
  • Isin T. Sakallioglu,
  • Robert Powers,
  • Patrick H. Dussault and
  • Raúl G. Barletta

Mycobacterium avium subspecies paratuberculosis (Map) is the etiologic agent of Johne’s disease in ruminants and has been associated with Crohn’s disease in humans. An effective control of Map by either vaccines or chemoprophylaxis is a p...

  • Article
  • Open Access
3 Citations
5,243 Views
19 Pages

Effects of a Change from an Indoor-Based Total Mixed Ration to a Rotational Pasture System Combined with a Moderate Concentrate Feed Supply on Immunological Cell and Blood Parameters of Dairy Cows

  • Julia Hartwiger,
  • Melanie Schären,
  • Jana Frahm,
  • Susanne Kersten,
  • Liane Hüther,
  • Helga Sauerwein,
  • Ulrich Meyer,
  • Gerhard Breves and
  • Sven Dänicke

In spring, transition from a total mixed ration (TMR) to a full grazing ration with moderate concentrate supply influences cow’s metabolism. It has been shown that feeding moderate amounts of concentrate during fulltime grazing did not prevent...

  • Article
  • Open Access
5 Citations
6,776 Views
19 Pages

2,4-Thiazolidinedione in Well-Fed Lactating Dairy Goats: I. Effect on Adiposity and Milk Fat Synthesis

  • Shana Jaaf,
  • Fernanda Rosa,
  • Misagh Moridi,
  • Johan S. Osorio,
  • Jayant Lohakare,
  • Erminio Trevisi,
  • Shelby Filley,
  • Gita Cherian,
  • Charles T. Estill and
  • Massimo Bionaz

Background: In a prior experiment, treatment of goats with the putative PPARγ agonist 2,4-thiazolidinedione (2,4-TZD) did not affect milk fat or expression of milk-fat related genes. The lack of response was possibly due to deficiency of vitami...

  • Discussion
  • Open Access
4,061 Views
7 Pages

The historical reliance of state and federal funds as a sole source of veterinary educational activities has created a funding gap at many academic institutions. Due to declining resources, philanthropy has become an important source of financial sup...

  • Case Report
  • Open Access
2 Citations
4,478 Views
6 Pages

The First Case of Botulism in a Donkey

  • Aliai Lanci,
  • Riccardo Rinnovati,
  • Fabrizio Anniballi,
  • Bruna Auricchio,
  • Concetta Scalfaro,
  • Marika Menchetti,
  • Alessandro Spadari and
  • Jole Mariella

Botulism, a severe neuroparalytic disease that can affect humans, all warm-blooded animals, and some fishes, is caused by exotoxins produced by ubiquitous, obligate anaerobic, spore-forming bacteria belonging to the genus Clostridium and named botuli...

  • Article
  • Open Access
14 Citations
5,564 Views
19 Pages

Severe and chronic low back pain is often associated with intervertebral disc (IVD) degeneration. While imposing a considerable socio-economic burden worldwide, IVD degeneration is also severely impacting on the quality of life of affected individual...

  • Article
  • Open Access
7 Citations
4,891 Views
14 Pages

Volatilome in Milk for Grana Padano and Parmigiano Reggiano Cheeses: A First Survey

  • Massimo Faustini,
  • Giovanni Quintavalle Pastorino,
  • Carla Colombani,
  • Luca Maria Chiesa,
  • Sara Panseri,
  • Daniele Vigo and
  • Giulio Curone

Milk characteristics in terms of volatile compounds can influence the subsequent product characteristics and can give indications about metabolism. These features can strongly depend on feeding and management. In this perspective, the screening of mi...

  • Feature Paper
  • Review
  • Open Access
129 Citations
21,807 Views
20 Pages

Forecasting Zoonotic Infectious Disease Response to Climate Change: Mosquito Vectors and a Changing Environment

  • Andrew W. Bartlow,
  • Carrie Manore,
  • Chonggang Xu,
  • Kimberly A. Kaufeld,
  • Sara Del Valle,
  • Amanda Ziemann,
  • Geoffrey Fairchild and
  • Jeanne M. Fair

Infectious diseases are changing due to the environment and altered interactions among hosts, reservoirs, vectors, and pathogens. This is particularly true for zoonotic diseases that infect humans, agricultural animals, and wildlife. Within the subse...

  • Article
  • Open Access
4 Citations
5,091 Views
11 Pages

Modification and Clinical Application of the Inner Perivitelline Membrane Test in Different Avian Species

  • Judith Krohn,
  • Dominik Fischer,
  • Helena Schneider,
  • Klaus Failing,
  • Michael Lierz,
  • Christine Ehling and
  • Axel Wehrend

12 April 2019

The aim of this study was to adapt an inner perivitelline membrane (IPVM) test as an interspecies penetration assay for avian spermatozoa. The IPVM of different bird species was evaluated to test the penetrating ability of avian spermatozoa in an int...

  • Feature Paper
  • Article
  • Open Access
23 Citations
5,295 Views
7 Pages

Increased Antimicrobial Resistance of MRSA Strains Isolated from Pigs in Spain between 2009 and 2018

  • Rossana Abreu,
  • Cristobalina Rodríguez-Álvarez,
  • María Lecuona,
  • Beatriz Castro,
  • Juan Carlos González,
  • Armando Aguirre-Jaime and
  • Ángeles Arias

The problem of emerging resistant microorganisms such as Methicillin-Resistant Staphylococcus aureus (MRSA) associated to livestock is closely linked to improper use of antimicrobial agents. The aim of this study is to find out the prevalence and cha...

  • Review
  • Open Access
13 Citations
8,162 Views
9 Pages

Cytokine Expression in Canine Lymphoma, Osteosarcoma, Mammary Gland Tumour and Melanoma: Comparative Aspects

  • Sergio Erdal Irac,
  • Annika Oksa,
  • Karen Jackson,
  • Aaron Herndon,
  • Rachel Allavena and
  • Chiara Palmieri

Cytokines released in the tumour microenvironment play a major role in cancer pathogenesis. In human cancers and corresponding animal models, cytokine expression contributes to tumour growth and progression, as well as regulation of the host anti-tum...

  • Article
  • Open Access
25 Citations
5,788 Views
8 Pages

In Vitro Anthelmintic Activity of Saponins Derived from Medicago spp. Plants against Donkey Gastrointestinal Nematodes

  • Michela Maestrini,
  • Aldo Tava,
  • Simone Mancini,
  • Federica Salari and
  • Stefania Perrucci

29 March 2019

With the aim to find new effective natural compounds for the control of nematodes, the in vitro anthelminthic properties of purified 1% saponins showing different chemical compositions and derived from Medicago sativa (MS), Medicago arborea (MA), Med...

  • Article
  • Open Access
13 Citations
6,720 Views
18 Pages

Comparative Analysis of the Liver Transcriptome among Cattle Breeds Using RNA-seq

  • Chandra Shekhar Pareek,
  • Mateusz Sachajko,
  • Jedrzej M. Jaskowski,
  • Magdalena Herudzinska,
  • Mariusz Skowronski,
  • Krzysztof Domagalski,
  • Joanna Szczepanek,
  • Urszula Czarnik,
  • Przymeslaw Sobiech and
  • Dibyendu Kumar
  • + 7 authors

29 March 2019

Global gene expression in liver transcriptome varies among cattle breeds. The present investigation was aimed to identify the differentially expressed genes (DEGs), metabolic gene networks and metabolic pathways in bovine liver transcriptome of young...

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Vet. Sci. - ISSN 2306-7381