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Tropical Medicine and Infectious Disease, Volume 10, Issue 9

2025 September - 37 articles

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Articles (37)

  • Article
  • Open Access
1,069 Views
21 Pages

In developing countries, adolescent girls and young women (AGYW) continue to experience high rates of unintended pregnancy and sexually transmitted infections (STIs), including Human Immunodeficiency Virus (HIV). Several healthcare services are avail...

  • Article
  • Open Access
1,220 Views
14 Pages

Development of a Microfluidic Point-of-Care Platform for HPV Detection Based on Helicase-Dependent Amplification

  • Everardo González-González,
  • Elda A. Flores-Contreras,
  • Gerardo de Jesús Trujillo-Rodríguez,
  • Mariana Lizbeth Jiménez-Martínez,
  • Iram P. Rodríguez-Sánchez,
  • Adriana Ancer-Arellano,
  • Salomon Alvarez-Cuevas,
  • Margarita L. Martinez-Fierro,
  • Iván A. Marino-Martínez and
  • Idalia Garza-Veloz

Human papillomavirus (HPV) is the most prevalent sexually transmitted infection worldwide and a leading cause of cervical cancer, accounting for over 300,000 deaths annually, primarily due to high-risk genotypes HPV-16 and HPV-18. Conventional molecu...

  • Article
  • Open Access
1 Citations
1,397 Views
11 Pages

Seroprevalence and Risk Factor for Canine Tick-Borne Disease in Urban–Rural Area in Ayacucho, Peru

  • Jime Rivera Villar,
  • Ivonne Aquino Escalante,
  • Saúl Chuchón Martínez,
  • Rilder Gastelú Quispe,
  • Ruth Huamán de la Cruz,
  • Aide Sandoval Juarez,
  • Giovanna Mendoza Mujica and
  • Nyshon Rojas Palomino

Ehrlichiosis and anaplasmosis are endemic to tropical and subtropical regions and pose significant zoonotic threats to both human and animal health. This study aimed to detect anti-Ehrlichia canis, anti-Borrelia burgdorferi, and anti-Anaplasma antibo...

  • Communication
  • Open Access
1,528 Views
18 Pages

Agreement Document for the Study of Leishmaniasis from a One Health Approach in Spain

  • Joaquina Martín-Sánchez,
  • Jose M. Requena,
  • Montserrat Gállego,
  • Maribel Jiménez,
  • Ricardo Molina,
  • Paul Nguewa,
  • Francisco Morillas-Márquez,
  • José M. Pérez-Victoria,
  • Begoña Monge-Maillo and
  • Clotilde Marín
  • + 1 author

Background: Leishmaniasis, a vector-borne disease caused by the parasite Leishmania, is a public health concern in Europe. Although Spain is an endemic country, it lacks a national surveillance network. To address this, the creation of a research and...

  • Article
  • Open Access
880 Views
16 Pages

Improved Utilisation and Quality of Blood Culture Services Following Operational Research in a Tertiary Hospital in Ghana

  • Rita Sewornu,
  • Emily Boakye-Yiadom,
  • Emmanuel Ativi,
  • Precious Kwablah Kwadzokpui,
  • Bismark Senahey,
  • Helena Owusu,
  • Pruthu Thekkur,
  • Ajay M. V. Kumar and
  • Cornelius C. Dodoo

Operational research (OR) published in 2023 revealed low utilisation and suboptimal quality of blood culture services at a tertiary hospital in Ghana. To address these, several interventions were implemented, including sensitisation of physicians, tr...

  • Article
  • Open Access
908 Views
16 Pages

Background: Various studies have shown that viral pneumonia pathogens display distinct inflammatory profiles, and hematological indices, such as the Neutrophil/Lymphocyte Ratio (NLR), Lymphocyte/Monocyte Ratio (LMR), and Platelet/Lymphocyte Ratio (PL...

  • Article
  • Open Access
911 Views
12 Pages

High Rate of Human T-Cell Lymphotropic Virus-2 in Patients with HIV in the Peruvian Amazon

  • Silvia Otero-Rodriguez,
  • Martin Casapia-Morales,
  • Carmen de Mendoza,
  • Viviana Pinedo-Cancino,
  • Seyer Mego-Campos,
  • Vicente Soriano,
  • Esperanza Merino and
  • José-Manuel Ramos-Rincón

HTLV-1/2 in people with HIV (PWH) has been little studied in the Peruvian Amazon, an endemic area for both viruses. We aimed to estimate its prevalence and describe the main clinical and epidemiological features of individuals with HTLV-HIV co-existe...

  • Article
  • Open Access
1,250 Views
17 Pages

Prevalence of Antimicrobial and Colistin Resistance in Enterobacterales in Healthy Pigs in Ghana Before and After Farmer Education

  • Elvis Fiam Amegayibor,
  • Rita Ohene Larbi,
  • Matilda Ayim-Akonor,
  • Ebenezer D. O. Ansa,
  • Pruthu Thekkur,
  • Helena Owusu,
  • Robert Fraser Terry,
  • Anthony D. Harries,
  • Benjamin Kissi Sasu and
  • Richael Odarkor Mills
  • + 1 author

High levels of antimicrobial resistance (AMR) were found in healthy pigs in the Greater Accra region of Ghana in 2022; this led to awareness creation and education of pig farmers about how to improve antimicrobial practices and biosecurity. To assess...

  • Article
  • Open Access
3 Citations
1,704 Views
15 Pages

Campylobacter Colonisation of Poultry Slaughtered at Nigerian Slaughterhouses: Prevalence, Antimicrobial Resistance, and Risk of Zoonotic Transmission

  • Emmanuel O. Njoga,
  • Philip P. Mshelbwala,
  • Akwoba J. Ogugua,
  • Excel C. Enemuo-Edo,
  • Onyinye S. Onwumere-Idolor,
  • Temitope M. Ogunniran,
  • Sunday N. Bernard,
  • Joel C. Ugwunwarua,
  • Ebube C. Anidobe and
  • James W. Oguttu
  • + 3 authors

Zoonotic Campylobacter species (ZCS), particularly C. jejuni and C. coli, cause major foodborne gastroenteritis and poultry is the principal reservoirs. However, there is limited data on Campylobacter transmission risk practices and antimicrobial res...

  • Article
  • Open Access
2,848 Views
19 Pages

Wastewater-Based Surveillance of SARS-CoV-2 and Modeling of COVID-19 Infection Trends

  • Wenli Wang,
  • Ruoyu Li,
  • Shilin Chen,
  • Liangping Chen,
  • Yu Jiang,
  • Jianjun Xiang,
  • Jing Wu,
  • Jing Li,
  • Zhiwei Chen and
  • Chuancheng Wu

Background: This study was performed to evaluate the early warning value of wastewater-based epidemiology (WBE) in monitoring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its correlation with population-level coronavirus disease 2...

  • Article
  • Open Access
899 Views
13 Pages

Asymptomatic Pneumococcal Carriage, Antimicrobial Resistance, and Associated Risk Factors Among Paediatric Healthcare Workers in Benin

  • Chakir Ishola Bello,
  • Cyriaque Comlan Degbey,
  • Yves Eric Denon,
  • Adolphe Adjanonhoun and
  • Lamine Baba-Moussa

Healthcare professionals (HCPs) working in paediatric settings are routinely exposed to respiratory pathogens, increasing their risk of asymptomatic colonisation by meningitis-associated bacteria. This study is the first to assess oropharyngeal and n...

  • Brief Report
  • Open Access
1,009 Views
7 Pages

Praziquantel Pretreatment Reduces Schistosoma japonicum Infection in Mice by Targeting Immature Worm Stages

  • Xiang Gui,
  • Rongxue Lv,
  • Haoran Zhong,
  • Hao Li,
  • Ke Lu,
  • Zhiqiang Fu,
  • Yamei Jin and
  • Jinming Liu

Schistosomiasis remains a significant public health concern, with Schistosoma japonicum infection endemic in certain regions of Asia. Praziquantel (PZQ), primarily known as an effective therapeutic agent, has recently shown potential as a prophylacti...

  • Case Report
  • Open Access
1,793 Views
10 Pages

Recurrent Malaria with Plasmodium vivax: A Case Report and Brief Review of the Literature

  • Ákos Vince Andrejkovits,
  • Adrian Vlad Pop,
  • Magdolna Fejér,
  • Elena Cristina Gîrbovan,
  • Răzvan Lucian Coșeriu,
  • Camelia Vintilă and
  • Anca Meda Văsieșiu

Background: Recurrent malaria refers to repeated episodes of the disease in the same individual. Plasmodium vivax is known for its ability to relapse due to dormant liver-stage hypnozoites and poses a particular risk to travelers returning from endem...

  • Article
  • Open Access
1 Citations
786 Views
11 Pages

In 2024, a significant pertussis surge in Queensland, Australia, strained public health resources. To improve investigation efficiency, the Wide Bay Public Health Unit introduced an online survey for pertussis cases on 1 August 2024, which collected...

  • Article
  • Open Access
1,614 Views
15 Pages

Operational Research Improves Compliance with Treatment Guidelines for Empirical Management of Urinary Tract Infection: A Before-and-After Study from a Primary Health Facility in Ghana

  • Elizabeth Boateng,
  • Helena Owusu,
  • Pruthu Thekkur,
  • George Kwesi Hedidor,
  • Oksana Corquaye,
  • Mercy N. A. Opare-Addo,
  • Florence Amah Nkansah,
  • Priscilla Vandyck-Sey,
  • Daniel Ankrah and
  • Charles Nii Kwadee Ofei-Palm

Compliance with standard treatment guidelines (STGs) for the empirical management of uncomplicated urinary tract infections (UTIs) ensures the rational use of antibiotics and mitigates antimicrobial resistance. Operational research (OR) at Korle Bu P...

  • Article
  • Open Access
939 Views
10 Pages

Prevalence and Screening Rates of Hepatitis B and Hepatitis C Infections in Adult Patients with Solitary Organ Tumors

  • Seyhmus Abakay,
  • Hüseyin Döngelli,
  • Nilay Danış,
  • Halil İbrahim Ellez,
  • Göksel Bengi,
  • Tuğba Yavuzşen and
  • Hüseyin Salih Semiz

Background and Aims: Hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) remain significant global public health issues despite advances in their diagnosis and treatment. Our country is in a medium endemic region...

  • Case Report
  • Open Access
1,412 Views
7 Pages

Nasal Myiasis Mimicking Allergic Rhinitis in Immunocompetent Adults: Case Series of 14 Adults

  • Sameh Mezri,
  • Mohamed Anas Ammar,
  • Latifa Mtibaa,
  • Sleheddine Mnasria,
  • Chiraz Halwani and
  • Khemaies Akkari

Background: Human nasal myiasis is a rare zoonotic infection caused by Oestrus ovis with a non-specific clinical presentation that can mimic more common conditions such as allergic rhinitis. Objective: To report a series of nasal myiasis cases in imm...

  • Brief Report
  • Open Access
2,582 Views
10 Pages

Backyard Livestock Guinea Pigs Are Reservoirs for Leptospira Shedding in Rural Households from Ecuador

  • Mauricio Xavier Salas-Rueda,
  • Fabricio Dugllay-Montaleza,
  • Darwin Paredes-Núñez,
  • Katherine Natalia Chávez Toledo,
  • Angel Sebastián Rodríguez-Pazmiño,
  • Elsy Carvajal,
  • Maria Belen Paredes-Espinosa,
  • Patricia Peralta-Ortiz,
  • Jairo Guama-Tipas and
  • Miguel Angel Garcia-Bereguiain
  • + 3 authors

Guinea pigs (Cavia porcellus) are bred as livestock in South American countries from the Andean region, including Ecuador. Despite their importance for the local rural economy, no public health management guidelines have ever been implemented for gui...

  • Article
  • Open Access
884 Views
12 Pages

Genetic Diversity of Plasmodium falciparum in Korhogo Health District, Northern Côte d’Ivoire

  • Edjronké M. A. Benié,
  • Carla Beuret,
  • Annina Schnoz,
  • Sara L. Cantoreggi,
  • Xavier C. Ding,
  • Kigbafori D. Silué and
  • Christian Nsanzabana

Understanding Plasmodium falciparum population genetic diversity is crucial to assess the impact of malaria control interventions. This study investigated P. falciparum genetic diversity using merozoite surface protein 1 (msp1), msp2 and glutamate-ri...

  • Article
  • Open Access
1,087 Views
18 Pages

Morbidity and Mortality Profile of Leishmaniasis in an Andean Region of Ecuador in the Context of Climate Change

  • Enma Veronica Páez-Espinosa,
  • Delia Maria Sosa-Guzmán,
  • Luis René Buitrón-Andrade,
  • Nicole Dávila-Jumbo,
  • Martín Israel Cáceres-Ruiz,
  • Vinicio Francisco Robalino-Flores and
  • Eugènia Mato-Matute

Leishmaniasis is a parasitic disease transmitted by female sandflies of the genus Lutzomyia. Ecuador is divided into three distinct natural regions: the Andes, the Coast, and Amazonia, each characterized by significant variations in altitude and clim...

  • Communication
  • Open Access
1,381 Views
14 Pages

Seropositivity for Pathogenic Leptospira in Dogs, Cats, and Horses at a Teaching Veterinary Hospital in Southern Chile

  • Lucía Azócar-Aedo,
  • Gloria Meniconi,
  • Carolina Pino-Olguín and
  • María Gallardo

At a veterinary hospital in southern Chile, we conducted an epidemiological study involving domestic dogs, cats, and horses to determine the seropositivity for pathogenic Leptospira spp., identify the infecting serogroups, measure antibody titers, an...

  • Article
  • Open Access
1,775 Views
11 Pages

Genotype Analysis on Orientia tsutsugamushi Causing Scrub Typhus in Malaysia: A Re-Emerging Disease

  • Shirley Yi Fen Hii,
  • Maswani Nabilah Mohd Zaidi,
  • Wan Norazanin Kassim,
  • Rohaidah Hashim and
  • Siti Roszilawati Ramli

Introduction: Scrub typhus is caused by Gram-negative bacteria, Orientia tsutsugamushi. Humans are the dead-end host of scrub typhus. Currently, there is no vaccine available. The disease can be fatal without appropriate treatment. Here, we present t...

  • Article
  • Open Access
1,647 Views
17 Pages

Vector-borne diseases (VBDs) account for more than 17% of all infectious diseases, causing over 700,000 deaths annually, particularly among the poorest populations in tropical and subtropical areas. Climate change, particularly global warming, and ce...

  • Article
  • Open Access
847 Views
15 Pages

Interleukin-8 Predicts Fatal Kala-Azar: A Case–Control Study

  • Simone Soares Lima,
  • Débora Cavalcante Braz,
  • Vladimir Costa Silva,
  • Teresinha de Jesus Cardoso Farias Pereira,
  • Líndia Kalliana da Costa Araújo Alves Carvalho,
  • Dorcas Lamounier Costa and
  • Carlos Henrique Nery Costa

Kala-azar is associated with case-fatality rates as high as 10% in certain regions. Early identification of mortality biomarkers can significantly reduce this risk. This study, strengthened by a relatively high number of kala-azar-related deaths, aim...

  • Communication
  • Open Access
1 Citations
1,128 Views
9 Pages

Compatibility of Serratia ureylitica Su_YN1, Malaria Transmission-Blocking Bacterium, with the Anopheles aquasalis Vector

  • Marília Andreza da Silva Ferreira,
  • Elen Sabrina dos Reis Martins,
  • Ricardo de Melo Katak,
  • Keillen Monick Martins Campos,
  • Elerson Matos Rocha,
  • Rosemary Aparecida Roque,
  • Pritesh Jaychand Lalwani,
  • Luciete Almeida Silva,
  • Edson Júnior do Carmo and
  • Claudia María Ríos-Velásquez
  • + 4 authors

Malaria continues to affect millions of people around the world. Current control strategies have not been sufficient, and additional tools are required for malaria elimination. A promising approach is the use of bacteria from the mosquito microbiota,...

  • Article
  • Open Access
1,436 Views
16 Pages

We aimed to compare the proportion of tuberculosis infection among social contacts of male tuberculosis Index case with and without alcohol use in the Puducherry district. A cross-sectional study using ego-centric approach was conducted between Novem...

  • Article
  • Open Access
1,627 Views
17 Pages

Diagnostic Accuracy of Antigen ELISA and Western Blot IgG for Neurocysticercosis in People Living with HIV/AIDS in Tanzania

  • Yakobo Lema,
  • Ulrich Fabien Prodjinotho,
  • Charles Makasi,
  • Marrywinnie A. Nanyaro,
  • Frank Asenga,
  • Andrew Kilale,
  • Sayoki Mfinanga,
  • Charlotte Rüther,
  • Andrea Sylvia Winkler and
  • Clarissa Prazeres da Costa
  • + 3 authors

Background: Neurocysticercosis (NCC) and HIV co-infection frequently occur in sub-Saharan Africa, yet the accuracy of available serological tests for NCC in immunosuppressed patients is uncertain. Methodology: We performed a cross-sectional diagnosti...

  • Article
  • Open Access
1,377 Views
15 Pages

Impaired Lung Function and Quality of Life Outcomes in Patients with Tuberculosis: A Cross-Sectional Study

  • Varshini Jagadeesh,
  • Prashanth Chikkahonnaiah,
  • Muskan Dubey,
  • Shashidhar H. Byrappa,
  • Hari Balaji Sridhar,
  • Raghavendra G. Amachawadi and
  • Ravindra P. Veeranna

Tuberculosis (TB) continues to be the world’s deadliest infectious disease, with an estimated 10.8 million new cases reported in 2023, of which India alone accounted for 28% of the global burden. This study aims to evaluate the impact of tuberc...

  • Review
  • Open Access
2,113 Views
13 Pages

Cutaneous leishmaniasis (CL) is a vector-borne parasitic disease caused by protozoa of the Leishmania genus. Once confined to endemic regions such as the Middle East, Americas, North Africa, and Central Asia, CL is increasingly emerging in non-endemi...

  • Article
  • Open Access
1,711 Views
14 Pages

Feasibility of Oral Rabies Vaccination of Dogs in Mexico

  • Verónica Gutiérrez Cedillo,
  • Luis Antonio Montoya Mondragón,
  • Jose Ramón Fernández Colín,
  • Katharina Bobe,
  • Ad Vos,
  • Luis Armando Lecuona Olivares and
  • Ruy López Ridaura

Mexico has not only successfully eliminated dog-mediated human rabies in recent years, but also the last rabies case in a dog infected with the canine variant of the rabies virus was reported in 2016. Mass dog vaccination campaigns were the cornersto...

  • Brief Report
  • Open Access
1 Citations
1,435 Views
9 Pages

Epidemiological and Clinical Characteristics of Stenotrophomonas maltophilia Isolates from Hospitalized Medical Patients; An Emerging Pathogen in the Non-Critically Ill

  • Dimitrios Kouroupis,
  • Charalampos Zarras,
  • Maria Zarfeiadou,
  • Christos Sanos,
  • Elias Iosifidis,
  • Chrysi Michailidou,
  • Konstantina Mpani,
  • Panagiotis Pateinakis,
  • Theocharis Koufakis and
  • Athina Pyrpasopoulou
  • + 3 authors

Until recently, Stenotrophomonas maltophilia was considered a low-virulence pathogen, usually found as an environmental commensal and colonizer of moist abiotic surfaces. Lately, it has increasingly been implicated in invasive infections with high as...

  • Article
  • Open Access
1,477 Views
10 Pages

Increase of Dengue in Pediatric Travelers in Madrid: A Multicentric Retrospective Experience

  • Isabel Mellado-Sola,
  • Sonia Milkova Ivanova,
  • Milagros García López Hortelano,
  • Paula Rodríguez-Molino,
  • Cinta Moraleda,
  • Sara Otero Alambillaga,
  • Rut Fernández Martín,
  • Francisco José Collado Díaz,
  • Aida Sánchez García and
  • Talía Sainz
  • + 2 authors

Dengue fever has significantly increased globally, extending into non-endemic regions. This study aims to describe the epidemiological and clinical characteristics of pediatric dengue cases diagnosed in Madrid, Spain, over ten years. We conducted a r...

  • Article
  • Open Access
1 Citations
1,307 Views
18 Pages

Identification of Statewide Hotspots for Respiratory Disease Targets Using Wastewater Monitoring Data

  • Dustin Servello,
  • Purnima Chalasani,
  • Erica Leasure,
  • Krysta Danielle LeMaster,
  • Justin Kellar,
  • Jill Stiverson,
  • Michelle White and
  • Zuzana Bohrerova

As wastewater monitoring networks continue to expand the monitoring of various targets, it is important to ensure these networks remain both representative of their monitored populations and flexible enough to accurately predict shifts in an expandin...

  • Article
  • Open Access
1,464 Views
22 Pages

Profiling HIV Risk and Determined, Resilient, Empowered AIDS-Free, Mentored, and Safe (DREAMS) Program Reach Among Adolescent Girls and Young Women (AGYW) in Namibia: Secondary Analysis of Population and Program Data

  • Enos Moyo,
  • Endalkachew Melese,
  • Hadrian Mangwana,
  • Simon Takawira,
  • Rosalia Indongo,
  • Bernadette Harases,
  • Perseverance Moyo,
  • Ntombizodwa Makurira Nyoni,
  • Kopano Robert and
  • Tafadzwa Dzinamarira

Background: Namibia is experiencing a generalized HIV epidemic, with 7.5% of the population living with HIV. Adolescent girls and young women (AGYW) aged 15–24 account for 28.6% of new infections annually. Various factors increase AGYW’s...

  • Article
  • Open Access
1 Citations
1,490 Views
15 Pages

Enterobacterales and Antimicrobial Resistance in Feed, Water, and Slurry in Pig Production Farms in the Greater Accra Region of Ghana, 2024

  • Elvis Fiam Amegayibor,
  • Rita Ohene Larbi,
  • Matilda Ayim-Akonor,
  • Richael Odarkor Mills,
  • Helena Owusu,
  • Benjamin Kissi Sasu,
  • Robert Fraser Terry,
  • Anthony D. Harries and
  • Florence S. Kuukyi

Increasing antimicrobial resistance (AMR) levels in Enterobacterales from pigs in Ghana prompted us to investigate farm feed, pig slurry, and farm water for Enterobacterales isolates, their antimicrobial resistance patterns, and antimicrobial residue...

  • Article
  • Open Access
1,396 Views
15 Pages

Evaluation of Hospitalizations for Tick-Borne Diseases in the United States from 2002 to 2021

  • Sidhvi Nekkanti,
  • Kirsten Hickok,
  • Mahesh Shrestha,
  • Eric Edewaard and
  • Thomas A. Melgar

Tick-borne diseases (TBDs) are a growing public health concern in the United States. This study analyzed 261,630 weighted hospitalizations from the Healthcare Cost and Utilization Project (HCUP) Nationwide Inpatient Sample (NIS) database between 2002...

  • Article
  • Open Access
1 Citations
4,753 Views
16 Pages

Long-Term Durability and Public Health Impact of City-Wide wMel Wolbachia Mosquito Releases in Niterói, Brazil, During a Dengue Epidemic Surge

  • Katherine L. Anders,
  • Gabriel Sylvestre Ribeiro,
  • Renato da Silva Lopes,
  • Pilar Amadeu,
  • Thiago Rodrigues da Costa,
  • Thais Irene Souza Riback,
  • Karlos Diogo de Melo Chalegre,
  • Wesley Pimentel de Oliveira,
  • Cátia Cabral da Silva and
  • Luciano A. Moreira
  • + 8 authors

In 2024, the Americas experienced the largest dengue outbreak on record and Brazil was among the worst affected countries, reporting 6.6 million cases and 6200 deaths. We report the long-term entomological and epidemiological effectiveness of city-wi...

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Trop. Med. Infect. Dis. - ISSN 2414-6366