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10 December 2019

Helicobacter Pylory and Oral Diseases †

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1
Department of Medicine and Surgery, Centre of Neuroscience,University of Milano-Bicocca, 20126 Milan, Italy
2
Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, 44121 Ferrara, Italy
3
Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania—Luigi Vanvitelli, 80138 Naples, Italy
4
Interdisciplinary Department of Medicine, University of Bari, 70121 Bari, Italy
Helicobacter pylori (H. pylori) gastric infection is considered one of the most common human infections. It occurs in half of the world’s population is the most common cause of adenocarcinoma of the distal stomach [1].
The risk in developing gastric cancer is believed to be related to differences among H. pylori strains and the inflammatory responses mediated by host genetic factors.
The accepted evidence is that the H. pylori strains reach the stomach by ingestion through the mouth, and because of its non-invasive nature, the stomach is the definitive site for colonization [2,3].
One of the key issues related to the eradication of gastric H. pylori has been the importance of oral hygiene and periodontal procedures. Dental plaque control and periodontal therapy can prevent gastric H. pylori infection recurrence for patients with gastric diseases associated with H. pylori [4].

Conflicts of Interest

The Authors declare no conflict of interest.

References

  1. Atherton, J.C.; Cao, P.; Peek, R.M., Jr.; Tummuru, M.K.; Blaser, M.J.; Cover, T.L. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration. J. Biol. Chem. 1995, 270, 17771–17777. [Google Scholar] [CrossRef] [PubMed]
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