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Chemistry, Volume 4, Issue 3

2022 September - 29 articles

Cover Story: A benzimidazolium-based organic cage was investigated as a potential antimicrobial and antifungal agent. The structure of the cage was obtained via synchrotron X-ray diffraction studies on single crystals of the cage, as hexafluorophosphate salt. The cage’s affinity for the nitrate anion was investigated by titration in pure acetonitrile, while the binding of chloride was investigated in a more competing medium (i.e., 20%v D2O/CD3CN). Considering the wide interest in (benz)imidazolium-based drugs, a series of experiments were performed to test the cytotoxicity of the cage compounds on a human-derived cell line, SH-SY5Y, and their potential application as antifungal and antibacterial agents. Preliminary investigations on the cage as an anion transporter across membranes were also performed. View this paper
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Articles (29)

  • Article
  • Open Access
9 Citations
3,460 Views
16 Pages

Sorption-Assisted Ultrafiltration Hybrid Method for Treatment of the Radioactive Aqueous Solutions

  • Leon Fuks,
  • Agnieszka Miśkiewicz and
  • Grażyna Zakrzewska-Kołtuniewicz

16 September 2022

The paper presents results of studies on the possibility of using the ultrafiltration method supported by sorption on low-cost, easily accessible aluminosilicates to purify water contaminated with radionuclides. An aqueous solution contaminated with...

  • Article
  • Open Access
3 Citations
4,407 Views
16 Pages

16 September 2022

Ni(CO)4, Cr(CO)6, Co(CO)3NO are some of the most common precursors used for focused electron beam induced deposition. Some of the compounds, even though extensively used have high requirements when it comes to handling being, explosives, highly flamm...

  • Article
  • Open Access
107 Citations
4,552 Views
16 Pages

15 September 2022

In this study, we used the FP-LAPW technique based on density functional theory applied in WIEN2k code to examine the structural, electronic, elastic, and thermoelectric properties of cubic double perovskite Rb2InBiX6 (X = Cl, Br) compounds. The stru...

  • Review
  • Open Access
26 Citations
4,672 Views
16 Pages

Fabrication of Polymersomes: A Macromolecular Architecture in Nanotherapeutics

  • Pragya Pallavi,
  • Karthick Harini,
  • Pemula Gowtham,
  • Koyeli Girigoswami and
  • Agnishwar Girigoswami

13 September 2022

In consideration of the issues of drug delivery systems, the artificial vesicle structures composed of block copolymers called polymersomes recently gained considerable attention. The possibility of tuning the mechanical parameter and increasing the...

  • Article
  • Open Access
3 Citations
2,869 Views
12 Pages

12 September 2022

The photodynamic therapy (PDT) represents a non-invasive method with good results in the treatment of superficial tumors. PDT is based on a combination of two factors, namely, a non-toxic photosensitizing molecule and a light source; the photosensiti...

  • Review
  • Open Access
2 Citations
4,094 Views
6 Pages

Hydrotrifluoromethylation of Styrene and Phenylacetylene Derivatives under Visible-Light Photoredox Conditions

  • Amel Souibgui,
  • Mongi ben Mosbah,
  • Ridha ben Salem,
  • Younes Moussaoui and
  • Anis Tlili

6 September 2022

Photoredox processes have emerged recently as a powerful tool for methodology developments. In this context, the hydrotrifluoromethylation of alkenes and alkynes using visible light photoredox methodologies has proven its efficiency these last years....

  • Article
  • Open Access
7 Citations
4,848 Views
27 Pages

6 September 2022

The human myeloid leukemia cell differentiation protein (hMcl-1) is an anti-apoptotic multi-partner protein, belonging to the B-cell lymphoma-2 (Bcl-2) family of proteins. Studies have linked hMcl-1 alleviated expression with resistance to hemopoieti...

  • Article
  • Open Access
19 Citations
3,946 Views
14 Pages

Novel Quinazolinone–Isoxazoline Hybrids: Synthesis, Spectroscopic Characterization, and DFT Mechanistic Study

  • Yassine Rhazi,
  • Mohammed Chalkha,
  • Asmae Nakkabi,
  • Imad Hammoudan,
  • Mohamed Akhazzane,
  • Mohamed Bakhouch,
  • Samir Chtita and
  • Mohamed El Yazidi

30 August 2022

Quinazolinone and isoxazoline systems have attracted much attention due to their interesting pharmacological properties. The association of these two pharmacophores in a single hybrid structure can boost the biological activity or bring a new one. In...

  • Review
  • Open Access
73 Citations
24,792 Views
29 Pages

Recent Advances in Synthesis and Properties of Pyrazoles

  • María-Camila Ríos and
  • Jaime Portilla

29 August 2022

Pyrazole-containing compounds represent one of the most influential families of N-heterocycles due to their proven applicability and versatility as synthetic intermediates in preparing relevant chemicals in biological, physical-chemical, material sci...

  • Article
  • Open Access
7 Citations
2,647 Views
9 Pages

Silver Ions Incorporation into Nanofibers for Enhanced hMSC Viability

  • Natalya A. Sitnikova,
  • Anastasiya O. Solovieva,
  • Elizaveta S. Permyakova,
  • Alexander N. Sheveyko,
  • Dmitry V. Shtansky and
  • Anton M. Manakhov

29 August 2022

Antimicrobial properties of silver have been known for a long time, but there is also cytotoxicity of high concentrations of silver. Therefore, it is important to select the concentration and shape of silver depending on the goals. The ideal wound dr...

  • Review
  • Open Access
71 Citations
14,141 Views
59 Pages

27 August 2022

Magnetic nanoparticles (MNPs) have evolved tremendously during recent years, in part due to the rapid expansion of nanotechnology and to their active magnetic core with a high surface-to-volume ratio, while their surface functionalization opened the...

  • Communication
  • Open Access
2 Citations
3,204 Views
7 Pages

Virus-like Cage Hybrid: Covalent Organic Cages Attached to Metal Organic Cage

  • Zhuoqian Lv,
  • Chenjuan Yu,
  • Xinyuan Zhu and
  • Youfu Wang

26 August 2022

A well-defined virus-like cage hybrid (VCH) with 24 covalent organic cages (COCs) attached to one metal organic cage (MOC) is presented here. The quantitative assembly of VCH was completed through coordination between soluble anisotropic COC bearing...

  • Communication
  • Open Access
9 Citations
3,493 Views
10 Pages

A Benzimidazolium-Based Organic Cage with Antimicrobial Activity

  • Sonia La Cognata,
  • Donatella Armentano,
  • Nicoletta Marchesi,
  • Pietro Grisoli,
  • Alessia Pascale,
  • Marion Kieffer,
  • Angelo Taglietti,
  • Anthony P. Davis and
  • Valeria Amendola

26 August 2022

Considering the wide interest in (benz)imidazolium-based drugs, we here report our study on a benzimidazolium-based organic cage as potential antimicrobial and antifungal agent. Cytotoxicity studies on a human derived cell line, SH-SY5Y, showed that...

  • Review
  • Open Access
13 Citations
4,395 Views
7 Pages

25 August 2022

Infrared spectroscopy is a widely used method of analysis to monitor various characteristics in the honey products analysis, to highlight these changes and to detect fraudulent modifications. In this way honey products could not be avoided. This arti...

  • Review
  • Open Access
12 Citations
5,836 Views
21 Pages

15 August 2022

Biominerals are extraordinary materials that provide organisms with a variety of functions to support life. The synthesis of biominerals and organization at the macroscopic level is a consequence of the interactions of these materials with proteins....

  • Article
  • Open Access
5 Citations
3,283 Views
16 Pages

15 August 2022

In the present study, the conversion performance of hydrogen sulfide (H2S) to elemental sulfur in ionic-liquid-incorporated transition metals (ILTMs) is predicted using a conductor-like screening model for realistic solvents (COSMO-RS). The predictio...

  • Review
  • Open Access
5 Citations
3,429 Views
15 Pages

On-Surface Chemistry on Low-Reactive Surfaces

  • Elie Geagea,
  • Frank Palmino and
  • Frédéric Cherioux

11 August 2022

Zero-dimensional (0D), mono-dimensional (1D), or two-dimensional (2D) nanostructures with well-defined properties fabricated directly on surfaces are of growing interest. The fabrication of covalently bound nanostructures on non-metallic surfaces is...

  • Article
  • Open Access
4 Citations
2,909 Views
10 Pages

9 August 2022

Two new ruthenium complexes with chelating-ether benzylidene ligands bearing a furan moiety were synthesized and characterized, including X-ray crystallography. They initiated fast, also at 0 °C, and were found to be highly active in a variety of...

  • Feature Paper
  • Article
  • Open Access
14 Citations
8,289 Views
10 Pages

An Easy and Reliable Method for the Mitigation of Deuterated Chloroform Decomposition to Stabilise Susceptible NMR Samples

  • Jan Teipel,
  • Vera Gottstein,
  • Eva Hölzle,
  • Katja Kaltenbach,
  • Dirk W. Lachenmeier and
  • Thomas Kuballa

2 August 2022

Highly reactive decomposition products of deuterated chloroform can deteriorate samples dissolved in this commonly used solvent for nuclear magnetic resonance (NMR) spectroscopy. Samples for metabolomics studies often contain a complex mixture of sen...

  • Article
  • Open Access
2,428 Views
11 Pages

28 July 2022

Enhancing photocarrier separation is a key step of photocatalysis, and in situ constructed composition interface is an advanced method to achieve this aim. Therefore, we report a face-to-face Bi2WO6/BiOCl (BWOC) which was synthesized via the continuo...

  • Article
  • Open Access
4 Citations
3,784 Views
12 Pages

26 July 2022

Supramolecular self-assembly in water resulting in polymeric structures is emerging because of its potential in the preparation of adaptive materials with applications in biology and medicine. Here, we report the first example of host molecules based...

  • Article
  • Open Access
11 Citations
4,215 Views
18 Pages

26 July 2022

The higher-order cycloaddition (HOCA) reaction of tropone with cyclopentadiene (Cp) has been studied within the Molecular Electron Density Theory. The Electron Localization Function (ELF) analysis of the electronic structure of tropone and Cp charact...

  • Article
  • Open Access
1 Citations
3,997 Views
18 Pages

Interligand Charge-Transfer Processes in Zinc Complexes

  • Carlo Ciarrocchi,
  • Guido Colucci,
  • Massimo Boiocchi,
  • Donatella Sacchi,
  • Maduka L. Weththimuni,
  • Alessio Orbelli Biroli and
  • Maurizio Licchelli

21 July 2022

Electron donor–acceptor (EDA) complexes are characterized by charge-transfer (CT) processes between electron-rich and electron-poor counterparts, typically resulting in a new absorption band at a higher wavelength. In this paper, we report a se...

  • Article
  • Open Access
4 Citations
8,858 Views
16 Pages

Spectrophotometric Determination of Formation Constants of Iron(III) Complexes with Several Ligands

  • José J. N. Segoviano-Garfias,
  • Gabriela A. Zanor,
  • Fidel Ávila-Ramos,
  • Egla Yareth Bivián-Castro and
  • Carlos A. Rubio-Jiménez

15 July 2022

Dye-sensitized solar cells transform solar light into electricity. One commonly used dye is a ruthenium complex. However, the use of ruthenium has been shown to have several disadvantages. In this study, via singular spectrum analysis using HypSpec s...

  • Article
  • Open Access
1 Citations
2,537 Views
20 Pages

Equilibrium Swelling of Thermo-Responsive Gels in Mixtures of Solvents

  • Aleksey D. Drozdov and
  • Jesper de Claville Christiansen

13 July 2022

Thermo-responsive (TR) gels of the LCST (lower critical solution temperature) type swell in water at temperatures below their volume phase transition temperature Tc and collapse above the critical temperature. When water is partially replaced with an...

  • Article
  • Open Access
3,089 Views
12 Pages

A New Study on the Eastern Flank of the Loma Blanca Deposit (Cuba) to Establish the Mineralogical, Chemical, and Pozzolanic Properties of Zeolitised Tuffs

  • Jorge L. Costafreda,
  • Domingo A. Martín,
  • Juan Herrera,
  • Jorge L. Costafreda-Velázquez,
  • Leticia Presa,
  • Ana García-Laso and
  • José Luis Parra

4 July 2022

The geological nature of the territory of the Republic of Cuba has favoured the formation of large and varied deposits of volcanic tuffs enriched by various species of zeolites. Today, new zeolite deposits continue to be discovered in the country. Th...

  • Article
  • Open Access
10 Citations
4,754 Views
14 Pages

Piperine Derivatives Enhance Fusion and Axonal Transport of Mitochondria by Activating Mitofusins

  • Lihong Zhang,
  • Xiawei Dang,
  • Antonietta Franco,
  • Haiyang Zhao and
  • Gerald W. Dorn

23 June 2022

Piperine (1-piperoylpiperidine) is the major pungent component of black pepper (Piper nigrum) and exhibits a spectrum of pharmacological activities. The molecular bases for many of piperine’s biological effects are incompletely defined. We note...

  • Communication
  • Open Access
4 Citations
4,145 Views
8 Pages

21 June 2022

A new synthesis strategy towards gold-coated silica nanoparticles is presented. The method provides an efficient, reliable and facile-coating process of well-defined star-shaped shell structures, characterized by UV-Vis, TEM, PXRD, DLS and zeta-poten...

  • Article
  • Open Access
9 Citations
5,270 Views
17 Pages

21 June 2022

The human ether-a-go-go-related gene (hERG) potassium channel is a well-known contributor to drug-induced cardiotoxicity and therefore is an extremely important target when performing safety assessments of drug candidates. Ligand-based approaches in...

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Chemistry - ISSN 2624-8549