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Transplantology, Volume 5, Issue 4

2024 December - 9 articles

Cover Story: Portal hypertension, a common consequence of cirrhosis, significantly impacts morbidity and mortality. Transjugular intrahepatic portosystemic shunt (TIPS) is frequently used as a bridge to liver transplant. It alleviates severe portal hypertension complications by shunting blood from the portal vein to systemic circulation. In patients with cirrhosis and advanced kidney dysfunction, simultaneous liver and kidney transplantation (SLK) offers substantial survival benefits. SLK candidates with TIPS may be sicker and more sensitized due to higher blood transfusion needs. TIPS can worsen pulmonary hypertension, a predictor of poor transplant outcomes. This study examines long-term outcomes of SLK recipients based on TIPS status, using data from the Scientific Registry of Transplant Recipients for comprehensive tracking of graft and recipient survival. View this paper
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Articles (9)

  • Article
  • Open Access
2,123 Views
9 Pages

Background: The accurate assessment of the glomerular filtration rate (GFR) in potential living kidney donors (PLKDs) is essential for successful transplantation and safeguarding kidney donation practice. Scintigraphy-measured GFR (mGFR) is widely re...

  • Review
  • Open Access
3,043 Views
14 Pages

A Half-Century of Heterotopic Heart Transplantation in Mice: The Spearhead of Immunology Research

  • Decheng Yin,
  • Oliver Dewald,
  • Xiangyu Peng,
  • Wenlong Nie,
  • Song Rong,
  • Diana Dudziak,
  • Christian H. K. Lehmann,
  • André Hoerning and
  • Jian Fu

Since the success of solid organ transplants, such as human kidneys, livers and hearts, from the 50s to the 60s in the last century, the field of organ transplantation has progressed rapidly. Mainly due to modifications in surgical operation techniqu...

  • Article
  • Open Access
3,596 Views
10 Pages

Effects of Tobacco Smoking on Post-Liver-Transplant Outcomes

  • Lovepreet Singh,
  • Ramanpreet Bajwa,
  • Sofia Molina Garcia,
  • Kristelle Imperio-Lagabon,
  • Omar T. Sims and
  • Jamak Modaresi Esfeh

Background/Objectives: Our study examined 5-year patient and graft survival outcomes among non-smokers, former smokers, and active smokers at the time of liver transplantation (LT) and immediate post-operative complications and short-term outcomes fo...

  • Article
  • Open Access
1,186 Views
8 Pages

Association of Acute Rejection and De Novo Renal Cell Carcinoma in Kidney Transplant Patients: An OPTN Data Analysis

  • Molly E. Casey,
  • Emmalie Yanacek,
  • Hitesh Kaul,
  • John P. Knorr,
  • Kamran Khanmoradi,
  • Afshin Parsikia,
  • Nikolaos Chandolias,
  • Kevin K. Zarrabi and
  • Radi Zaki

Background: Kidney Transplant Recipients (KTRs) are at risk of renal cell carcinoma (RCC). The risk of RCC in KTRs is approximated to be 5–10 times higher compared with the general population. A relation between kidney rejection and renal malig...

  • Article
  • Open Access
4 Citations
1,659 Views
9 Pages

Diversifying Kidney Transplant Education: Assessing the Artificial Intelligence-Powered Capability of ChatGPT

  • Badi Rawashdeh,
  • Joohyun Kim,
  • Ty Dunn,
  • Haneen Al-Abdallat,
  • Ahmad Qasem,
  • Rootvij Bhatt,
  • Raj Prasad and
  • Matthew Cooper

Background: Artificial intelligence (AI) has rapidly advanced, significantly impacting medicine. ChatGPT, a new AI model, generates responses based on user input. This study evaluates ChatGPT’s ability to assist with pre- and post-kidney transp...

  • Case Report
  • Open Access
2,013 Views
8 Pages

Renal Collecting System Calcified Hematoma Following Parenchymal Perforation by Ureteral Stent in Kidney Transplantation: A Case Report

  • Octavio Herrera,
  • Alexis Garza,
  • Maria Veronica Rodriguez,
  • Manuel De Jesus-Escano,
  • Samuel Serna,
  • Jose Almeda and
  • Gaudencio Olgin

Introduction: Renal parenchymal perforation by ureteral stent placement is a rare but serious complication. There is also a paucity of data regarding collecting system hematomas and potential calcification in renal allografts. Case presentation: We r...

  • Case Report
  • Open Access
1,491 Views
5 Pages

Portal inflow modulation has become standard practice in many transplant centers performing living donor liver transplantation. This is believed to counteract the deleterious effects of excess portal flow into a small-for-size graft. A splenectomy ne...

  • Article
  • Open Access
1,654 Views
12 Pages

Use of a Facebook Support Group for Kidney Transplant Patients

  • Tenzin Yongye,
  • Maria Keller,
  • Surjo Bandyopadhyay,
  • Ahmad Zaaroura and
  • Liise K. Kayler

Background: Facebook groups have been used to foster social support of transplant patients. Examining the use and content strategies for generating member interactions within transplant-specific groups can inform how we leverage these groups to expan...

  • Article
  • Open Access
2,106 Views
12 Pages

Outcomes of Simultaneous Liver–Kidney Transplant Recipients According to Pre-Transplant Transjugular Intrahepatic Portosystemic Shunt (TIPS) in the United States

  • Tristan Meier,
  • Kathryn Schmidt,
  • Kristin Cole,
  • Jody C. Olson,
  • Timucin Taner,
  • Douglas A. Simonetto and
  • Samy Riad

Background: Previous data suggested that the outcomes for liver-alone transplant recipients following transjugular intrahepatic portosystemic shunt (TIPS) insertion were comparable to those without TIPS. This study investigates the association betwee...

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Transplantology - ISSN 2673-3943