BioMedInformatics, Volume 3, Issue 2

Myocardial Infarction (MI) is the death of the heart muscle caused by lack of oxygenated blood flow to the heart muscle. It has been the main cause of death worldwide. The fastest way to detect MI is by using an electrocardiogram (ECG) device, which...

Background: According to GWAS, which analyzes large amounts of DNA variants in case-control strategies, the genetic differences between two human individuals do not exceed 0.5%. As a consequence, finding biological significance in GWAS results is a c...

Facial palsy (FP) is a neurological disorder that affects the facial nerve, specifically the seventh nerve, resulting in the patient losing control of the facial muscles on one side of the face. It is an annoying condition that can occur in both chil...

Urine output is an important indicator of renal function. In hospitals, urine is collected using a catheter connected to a urine collection bag that has volume gradation markings. This type of visual measurement has low levels of accuracy and is labo...

DNA methylation acts as a major epigenetic modification in mammals, characterized by the transfer of a methyl group to a cytosine. DNA methylation plays a pivotal role in regulating normal development, and misregulation in cells leads to an abnormal...

In this study, we propose a closed-loop insulin administration framework for multiple daily injection (MDI) treatment using a reinforcement learning (RL) agent for insulin bolus therapy. The RL agent, based on the soft actor–critic (SAC) algori...

The recent advances in deep learning have revolutionised computer-aided diagnosis in medical imaging. However, deep learning approaches to unveil their full potential require significant amounts of data, which can be a challenging task in some scient...

Networks form the backbone of any healthcare system. Various databases were searched with relevant keywords, data were abstracted, and numerous papers were appraised for this synthesis. This compiled systematic review gives a comprehensive overview o...

Access to the three-dimensional (3D) structural information of macromolecules is of major interest in both fundamental and applied research. Obtaining this experimental data can be complex, time consuming, and costly. Therefore, in silico computation...

Breast cancer is the most prevalent form of cancer and the primary cause of cancer-related mortality among women globally. Breast cancer diagnosis involves multiple variables, making it a complex process. Therefore, the accurate estimation of feature...

The COVID-19 virus has made a huge impact on people’s lives ever since the outbreak happened in December 2019. Unfortunately, the COVID-19 virus has not completely vanished from the world yet, and thus, global agitation is still increasing with...

Over the past decade, omics technologies such as genomics, epigenomics, transcriptomics, proteomics, and metabolomics have been used in the scientific understanding of diseases. While omics technologies have provided a useful tool for the diagnosis a...

Transmembrane proteins (TMPs) are a class of essential proteins for biological and therapeutic purposes. Despite an increasing number of structures, the gap with the number of available sequences remains impressive. The choice of a dedicated function...

The restoration of osseous defects is accomplished by bone grafts and bone substitutes, which are also called biomaterials. Autogenous grafts, which are derived from the same individual, can retain the viability of cells, mainly the osteoblasts and o...

The reduction of childhood mortality is an ongoing struggle and a commonly used factor in determining progress in the medical field. The under-5 mortality number is around 5 million around the world, with many of the deaths being preventable. In ligh...

Holliday junctions are the first recognized templates of legitimate recombination. Their prime physiological role is meiotic homologous recombination, resulting in rearrangements of the genetic material. In humans, recombination hotspots follow a dis...