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Biologics, Volume 4, Issue 3

2024 September - 6 articles

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Articles (6)

  • Article
  • Open Access
1 Citations
2,433 Views
19 Pages

Hydrolysates of Chicken Byproducts and Their Effect on the Histological and Histopathological Analysis of Liver and Kidney in a Murine Model of Induced Metabolic Syndrome

  • Martha Guillermina Romero-Garay,
  • Efigenia Montalvo-González,
  • Odila Saucedo-Cárdenas,
  • Eduardo Mendeleev Becerra-Verdín,
  • Adolfo Soto-Domínguez,
  • Cristian Rodríguez-Aguayo and
  • María de Lourdes García-Magaña

20 September 2024

This study investigated the potential of chicken byproduct hydrolysates (CBH) characterized by a mixture of low-molecular-weight peptides (<1.35 kDa) and larger peptides (<17.5 kDa) as a treatment for metabolic syndrome (MS), from a histologica...

  • Review
  • Open Access
2 Citations
5,733 Views
31 Pages

Unveiling Novel Insights in Helminth Proteomics: Advancements, Applications, and Implications for Parasitology and Beyond

  • Nooshinmehr Soleymani,
  • Soheil Sadr,
  • Cinzia Santucciu,
  • Shiva Dianaty,
  • Narges Lotfalizadeh,
  • Ashkan Hajjafari,
  • Fatemeh Heshmati and
  • Hassan Borji

19 September 2024

Helminths have developed intricate mechanisms to survive and evade the host’s immune responses. Hence, understanding the excretory-secretory products (ESPs) by helminths is crucial for developing control tools, including drug targets, vaccines,...

  • Article
  • Open Access
1 Citations
4,130 Views
20 Pages

Characterization of Critical Quality Attributes of an Anti-PCSK9 Monoclonal Antibody

  • Thayana A. Cruz,
  • Nicholas R. Larson,
  • Yangjie Wei,
  • Natalia Subelzu,
  • Yaqi Wu,
  • Christian Schöneich,
  • Leda R. Castilho and
  • Charles Russell Middaugh

11 September 2024

During early development of biopharmaceuticals, suboptimal producing clones and production conditions can result in limited quantities of high-purity products. Here we describe a systematic approach, which requires minimal amounts of protein (~10 mg)...

  • Review
  • Open Access
3,994 Views
14 Pages

30 August 2024

Inflammatory bowel disease (IBD), which encompasses both ulcerative colitis (UC) and Crohn’s disease (CD), is a major health burden worldwide. There are increasing concerns surrounding the impacts of this disease due to significant rises in the...

  • Feature Paper
  • Review
  • Open Access
6 Citations
8,921 Views
38 Pages

15 August 2024

The solute carrier family 35 (SLC35) comprises multiple members of transporters, including a group of proteins known as nucleotide sugar transporters (NSTs), an adenosine triphosphate (ATP) transporter, 3′-phosphoadenosine 5′-phosphosulfa...

  • Article
  • Open Access
2 Citations
3,589 Views
10 Pages

The Effect of Sample Handling on Rabies-Neutralizing Antibody Stability

  • Samantha J. Pralle,
  • Stephanie K. Gatrell,
  • Cassidy C. Keating and
  • Susan M. Moore

12 July 2024

The measurement of rabies-neutralizing antibody is important for monitoring the response to rabies vaccination. For all the purposes of measurement, such as routine monitoring of vaccine response in humans and animals, serosurveys, and biologics qual...

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Biologics - ISSN 2673-8449