Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.2
2.7
Journals
Animals
Special Issues
The Application of Platelet-Derived Products for Tissue Regeneration in Companion...
share announcement

The Application of Platelet-Derived Products for Tissue Regeneration in Companion and Farm Animals

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".

Deadline for manuscript submissions: 28 February 2026 | Viewed by 778

Special Issue Editors

Dr. Luca Melotti

E-Mail Website
Guest Editor
Department of Comparative Biomedicine and Food Science BCA, University of Padova, Padova, Italy
Interests: regenerative medicine; adult stem cells; skin tissue engineering; skin wound healing
Dr. Marco Patruno

E-Mail Website
Guest Editor
Department of Comparative Biomedicine and Food Science BCA, University of Padova, Padova, Italy
Interests: stem cells; cell biology; immunohistochemistry muscle; regenerative medicine; tissue engineering

Special Issue Information

Dear Colleagues,

The increasing application of platelet-derived products (PDPs), such as platelet-rich plasma (PRP) or platelet lysate (PL), can be attributed to their high content of bioactive molecules, including growth factors and cytokines, crucial for tissue repair and regeneration. These products are derived from minimally invasive procedures and have shown significant therapeutic benefits. However, the veterinary field faces challenges due to the absence of standardized protocols for producing PDPs, which hinders the evaluation and widespread adoption of PDP-based treatments.

The aim of this Special Issue is to describe the most recent advances in the application of PDPs as a therapeutic for tissue regeneration in veterinary medicine. Contributions on the novel formulation of PDPs and in vitro studies describing the mechanisms of action and innovative techniques for PDPs isolation are highly encouraged. These submissions could improve the state of the art about the application of PDPs in veterinary medicine by helping the scientific community standardize and enhance PDPs’ potential in veterinary regenerative medicine and tissue engineering (TERM). Researchers are invited to submit original research papers, case studies, or reviews that focus on the study of PDPs in veterinary medicine.

Dr. Luca Melotti
Dr. Marco Patruno
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

 

Keywords

  • platelet-derived products
  • platelet-rich plasma
  • tissue engineering
  • regenerative medicine
  • stem cells
  • platelet lysate
  • innovative therapy

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Other

24 pages, 2508 KB  
Systematic Review
Platelet-Rich Plasma in Equine Osteoarthritis: A Systematic Review of Clinical and Experimental Evidence
by Jorge U. Carmona and Catalina López
Animals 2025, 15(18), 2647; https://doi.org/10.3390/ani15182647 - 9 Sep 2025
Viewed by 548
Abstract
Osteoarthritis (OA) is a major cause of equine lameness, with few effective disease-modifying treatments. This systematic review, conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, evaluated the efficacy of platelet-rich plasma (PRP) for equine OA by analyzing 11 [...] Read more.
Osteoarthritis (OA) is a major cause of equine lameness, with few effective disease-modifying treatments. This systematic review, conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, evaluated the efficacy of platelet-rich plasma (PRP) for equine OA by analyzing 11 studies (6 clinical, 5 experimental) identified through Web of Science, Scopus, and PubMed (2000–2024). The screening process identified 252 records, of which 136 were duplicates and 105 were excluded based on predefined criteria. The analysis showed that intra-articular PRP injections are generally safe, with transient synovial inflammation occurring mainly when PRP was activated with bovine thrombin. Both leukocyte-rich (L-PRP) and leukocyte-poor (P-PRP) formulations exhibited comparable efficacy, though optimal platelet concentrations (423–658 × 103/μL) and dosing regimens remain undefined. A PRISMA-based quality assessment highlighted substantial variability in study design, with clinical trials constrained by small sample sizes and high risk of bias. Experimental studies confirmed PRP’s biological activity but showed inconsistencies in preparation methods. The findings indicate that PRP activation is unnecessary and may even be pro-inflammatory, that multiple injections could improve outcomes, and that reporting of cellular composition is inconsistent across studies. The PRISMA framework identified critical evidence gaps, particularly regarding long-term efficacy and protocol standardization. These results emphasize the need for PRISMA-compliant randomized controlled trials featuring standardized PRP protocols, validated outcome measures, and extended follow-up periods to establish evidence-based guidelines for managing equine OA. Full article
(This article belongs to the Special Issue The Application of Platelet-Derived Products for Tissue Regeneration in Companion and Farm Animals)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop