Metabolic Disorders of Poultry

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Poultry".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 1338

Special Issue Editors


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Guest Editor
Department of Animal Science, Iowa State University, Ames, IA, USA
Interests: animal production; poultry nutrition; environmental physiology; gut health, immunology; alternative feed ingredients; nutrient metabolism

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Guest Editor
1. Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China
2. State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China
3. Key Laboratory of Livestock and Poultry Multi-Omics, Ministry of Agriculture and Rural Affairs, Sichuan Agricultural University, Chengdu 611130, China
Interests: feed additives; fatty liver syndrome; lipid metabolism; genetics and breeding; immunology; gut microbiology; reactive oxygen species (ros); autophagy; follicular atresia; chicken chondrocyte proliferation

Special Issue Information

Dear Colleagues,

Over the last few decades, the incidence of metabolic disorders in poultry production has increased, accounting for huge economic losses in the poultry industry. This has been exacerbated owing to the rapid improvements in the genetic potential of poultry for faster growth and improved feed efficiency. Metabolic problems such as pulmonary hypertension syndrome, muscle myopathy, skeletal disorders, ascites, sudden death fatty liver hemorrhagic syndrome, etc., have become prevalent in poultry. These disorders are not related to infectious diseases; rather, they occur due to dysfunctions in metabolic processes, including the inability of the body to keep up with the demand for an increased metabolism, rapid growth rate, or higher egg production, resulting in morbidity and/or mortality. However, implementing appropriate modifications to the environment, nutrition, and managerial needs of poultry can help ameliorate these events.

This Special Issue aims to collate original research and review articles addressing metabolic disorders affecting poultry productivity, health, and welfare. Research areas may include (but are not limited to) disorders occurring due to genetic causes, nutritional challenges, environmental or management conditions, and, where necessary, the intervention strategies adopted to alleviate these metabolic problems and optimize poultry production.

We invite you to share your recent findings through this Special Issue.

Dr. Victoria Anthony Uyanga
Dr. Felix Kwame Amevor
Guest Editors

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Keywords

  • poultry
  • metabolic disorder
  • skeletal disorders
  • nutritional deficiencies
  • heat stress
  • ascites
  • sudden death syndrome
  • fatty liver hemorrhage syndrome
  • nutrition
  • welfare

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Published Papers (1 paper)

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Research

13 pages, 2563 KiB  
Article
Non-Targeted Metabolomics of Serum Reveals Biomarkers Associated with Body Weight in Wumeng Black-Bone Chickens
by Zhong Wang, Xuan Yu, Shenghong Yang, Mingming Zhao and Liqi Wang
Animals 2024, 14(18), 2743; https://doi.org/10.3390/ani14182743 - 23 Sep 2024
Viewed by 672
Abstract
Growth performance is an important economic trait of broilers but the related serum metabolomics remains unclear. In this study, we utilized non-targeted metabolomics using ultra-high-performance liquid phase tandem mass spectrometry (UHPLC-MS/MS) to establish metabolite profiling in the serum of Chinese Wumeng black-bone chickens. [...] Read more.
Growth performance is an important economic trait of broilers but the related serum metabolomics remains unclear. In this study, we utilized non-targeted metabolomics using ultra-high-performance liquid phase tandem mass spectrometry (UHPLC-MS/MS) to establish metabolite profiling in the serum of Chinese Wumeng black-bone chickens. The biomarker metabolites in serum associated with growth performance of chickens were identified by comparing the serum metabolome differences between chickens that significantly differed in their weights at 160 days of age when fed identical diets. A total of 766 metabolites were identified including 13 differential metabolite classes such as lipids and lipid-like molecules, organic acids and their derivatives, and organoheterocyclic compounds. The results of difference analysis using a partial least squares discriminant analysis (PLS-DA) model indicated that the low-body-weight group could be differentiated based on inflammatory markers including prostaglandin a2, kynurenic acid and fatty acid esters of hydroxy fatty acids (FAHFA), and inflammation-related metabolic pathways including tryptophan and arachidonic acid metabolism. In contrast, the sera of high-body-weight chickens were enriched for riboflavin and 2-isopropylmalic acid and for metabolic pathways including riboflavin metabolism, acetyl group transfer into mitochondria, and the tricarboxylic acid (TCA) cycle. These results provide new insights into the practical application of improving the growth performance of local chickens. Full article
(This article belongs to the Special Issue Metabolic Disorders of Poultry)
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