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Animals
Special Issues
Production, Breeding and Disease Management of Plateau Animals
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Production, Breeding and Disease Management of Plateau Animals

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal System and Management".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 2426

Special Issue Editors

Prof. Dr. Jiakui Li

E-Mail Website
Guest Editor
1. College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
2. College of Animals Husbandry and Veterinary Medicine, Tibet Agricultural and Animal Husbandry University, Linzhi, China
Interests: microbiota; nutrition; yaks; poultry; disease management; probiotics
Dr. Md. F. Kulyar

E-Mail Website
Guest Editor
Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, China
Interests: toxicity; nutrition; probiotics; bone disorders; disease management
Dr. Quan Mo

E-Mail Website
Guest Editor
Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, China
Interests: poultry; feed toxicity; thiram; animal production

Special Issue Information

Dear Colleagues,

We are excited to propose a forthcoming Special Issue that will delve into the captivating realm of Plateau animals—a remarkable ecosystem that continues to inspire researchers and enthusiasts alike. Titled "Production, Breeding and Disease Management of Plateau Animals", this Special Issue of cutting-edge studies aims to offer a comprehensive exploration of the diverse facets of animal life on the Plateau. With a focus on recent emerging viral risks and their effects on the population, we anticipate ground-breaking research that offers novel insights into identifying infections in this Special Issue. We also expect investigations that will provide light on the probiotic potential of yaks, revealing their function in boosting gut health and development.

Additionally, we are eager to investigate the complex interactions across microbial communities, with a focus on how probiotics affect gut growth and the microbiome makeup. The importance of early diagnosis and control of zoonotic disease will be highlighted through research that addresses important issues linked to parasitic infections. We want to encourage cooperation and knowledge sharing among researchers and academic specialists concerned with the welfare of Plateau animals through this Special Issue. We will all work together to advance knowledge and develop new methods for breeding, production, and disease control, which will help to protect and thrive these amazing creatures in their special ecology. We look forward to receiving cutting-edge research from experts throughout the world as they contribute their knowledge and ideas to this Special Issue. By collaborating, we may overcome the difficulties and complexity that occur in the process and make substantial advancements in our comprehension of ruminant biology.

Warm regards,

Prof. Dr. Jiakui Li
Dr. Md. F. Kulyar
Dr. Quan Mo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Plateau animals
  • production
  • breeding
  • disease management
  • Qinghai–Tibet Plateau

Published Papers (2 papers)

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Research

15 pages, 10668 KiB  
Article
Metagenomic Analysis Reveals A Gut Microbiota Structure and Function Alteration between Healthy and Diarrheic Juvenile Yaks
by Hongwen Zhao, Quan Mo, Muhammad Fakhar-e-Alam Kulyar, Jiuqiang Guan, Xiangfei Zhang, Xiaolin Luo and Jiakui Li
Animals 2024, 14(8), 1181; https://doi.org/10.3390/ani14081181 - 14 Apr 2024
Viewed by 721
Abstract
Diarrhea-induced mortality among juvenile yaks is highly prevalent in the pastoral areas of the Qinghai-Tibet plateau. Although numerous diseases have been linked to the gut microbial community, little is known about how diarrhea affects the gut microbiota in yaks. In this work, we [...] Read more.
Diarrhea-induced mortality among juvenile yaks is highly prevalent in the pastoral areas of the Qinghai-Tibet plateau. Although numerous diseases have been linked to the gut microbial community, little is known about how diarrhea affects the gut microbiota in yaks. In this work, we investigated and compared changes in the gut microbiota of juvenile yaks with diarrhea. The results demonstrated a considerable drop in the alpha diversity of the gut microbiota in diarrheic yaks, accompanied by Eysipelatoclostridium, Parabacteroides, and Escherichia-Shigella, which significantly increased during diarrhea. Furthermore, a PICRust analysis verified the elevation of the gut–microbial metabolic pathways in diarrhea groups, including glycine, serine, and threonine metabolism, alanine, aspartate, oxidative phosphorylation, glutamate metabolism, antibiotic biosynthesis, and secondary metabolite biosynthesis. Taken together, our study showed that the harmful bacteria increased, and beneficial bacteria decreased significantly in the gut microbiota of yaks with diarrhea. Moreover, these results also indicated that the dysbiosis of the gut microbiota may be a significant driving factor of diarrhea in yaks. Full article
(This article belongs to the Special Issue Production, Breeding and Disease Management of Plateau Animals)
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31 pages, 29044 KiB  
Article
Study of Transcriptomic Analysis of Yak (Bos grunniens) and Cattle (Bos taurus) Pulmonary Artery Smooth Muscle Cells under Oxygen Concentration Gradients and Differences in Their Lung Histology and Expression of Pyruvate Dehydrogenase Kinase 1-Related Factors
by Yiyang Zhang, Manlin Zhou, Yuxin Liang, Rui Li, Lan Zhang, Shuwu Chen, Kun Yang, Haie Ding, Xiao Tan, Qian Zhang and Zilin Qiao
Animals 2023, 13(22), 3450; https://doi.org/10.3390/ani13223450 - 8 Nov 2023
Viewed by 1300
Abstract
The aim of this study was to investigate the molecular mechanisms by which hypoxia affects the biological behavior of yak PASMCs, the changes in the histological structure of yak and cattle lungs, and the relationships and regulatory roles that exist regarding the differences [...] Read more.
The aim of this study was to investigate the molecular mechanisms by which hypoxia affects the biological behavior of yak PASMCs, the changes in the histological structure of yak and cattle lungs, and the relationships and regulatory roles that exist regarding the differences in the distribution and expression of PDK1 and its hypoxia-associated factors screened for their role in the adaptation of yak lungs to the plateau hypoxic environment. The results showed that, at the level of transcriptome sequencing, the molecular regulatory mechanisms of the HIF-1 signaling pathway, glucose metabolism pathway, and related factors (HK2/PGK1/ENO1/ENO3/ALDOC/ALDOA) may be closely related to the adaptation of yaks to the hypoxic environment of the plateau; at the tissue level, the presence of filled alveoli and semi-filled alveoli, thicker alveolar septa and basement membranes, a large number of erythrocytes, capillary distribution, and collagen fibers accounted for all levels of fine bronchioles in the lungs of yaks as compared to cattle. A higher percentage of goblet cells was found in the fine bronchioles of yaks, and PDK1, HIF-1α, and VEGF were predominantly distributed and expressed in the monolayers of ciliated columnar epithelium in the branches of the terminal fine bronchioles of yak and cattle lungs, with a small amount of it distributed in the alveolar septa; at the molecular level, the differences in PDK1 mRNA relative expression in the lungs of adult yaks and cattle were not significant (p > 0.05), the differences in HIF-1α and VEGF mRNA relative expression were significant (p < 0.05), and the expression of PDK1 and HIF-1α proteins in adult yaks was stronger than that in adult cattle. PDK1 and HIF-1α proteins were more strongly expressed in adult yaks than in adult cattle, and the difference was highly significant (p < 0.01); the relative expression of VEGF proteins was not significantly different between adult yaks and cattle (p > 0.05). The possible regulatory relationship between the above results and the adaptation of yak lungs to the plateau hypoxic environment paves the way for the regulatory mechanisms of PDK1, HIF-1α, and VEGF, and provides basic information for studying the mechanism of hypoxic adaptation of yaks in the plateau. At the same time, it provides a reference for human hypoxia adaptation and a target for the prevention and treatment of plateau diseases in humans and plateau animals. Full article
(This article belongs to the Special Issue Production, Breeding and Disease Management of Plateau Animals)
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