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Animals
Special Issues
Use of Regenerative Therapies in Canine Osteoarthritis: Volume II
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Use of Regenerative Therapies in Canine Osteoarthritis: Volume II

A special issue of Animals (ISSN 2076-2615).

Deadline for manuscript submissions: 31 December 2024 | Viewed by 959

Special Issue Editors

Dr. Angela Palumbo Piccionello

E-Mail Website
Guest Editor
School of Bioscience and Veterinary Medicine, University of Camerino, 62024 Matelica, Italy
Interests: orthopedics; regenerative therapy; stem cells; PRP; traumatology; osteoarthritis
Special Issues, Collections and Topics in MDPI journals
Dr. Caterina Di Bella

E-Mail Website1 Website2
Guest Editor
School of Bioscience and Veterinary Medicine, University of Camerino, 62024 Matelica, Italy
Interests: anaesthesia; pain management; loco-regional anaesthesia; analgesic therapies
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Regenerative therapies, in human medicine as in pets, are fully entering the treatment of numerous pathologies. Surprisingly, even in orthopedics, studies on the use of PRP, other blood products, and stem cells alone or through micrografts are demonstrating very interesting results. The purpose of this Special Issue is to collect the most modern acquisitions, conducted with methodological rigor, in the veterinary orthopedics field to provide Animals reader with continuous updates.

Dr. Angela Palumbo Piccionello
Dr. Caterina Di Bella
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bone

  • joint
  • osteosynthesis
  • osteoarthritis
  • adipose micrograft
  • stem cells

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Published Papers (1 paper)

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Research

15 pages, 281 KiB  
Article
Efficacy of a Single Injection of Stromal Vascular Fraction in Dogs with Elbow Osteoarthritis: A Clinical Prospective Study
by Yvonne Bruns, Maike Schroers, Stephanie Steigmeier-Raith, Anja-Christina Waselau, Sven Reese and Andrea Meyer-Lindenberg
Animals 2024, 14(19), 2803; https://doi.org/10.3390/ani14192803 - 28 Sep 2024
Viewed by 548
Abstract
This study aimed to assess the efficacy of a single intra-articular injection of autologous stromal vascular fraction (SVF) in dogs with chronic lameness due to advanced elbow osteoarthritis (OA) that were unresponsive to conventional drug therapy. In this clinical, prospective, non-blinded, single-center study, [...] Read more.
This study aimed to assess the efficacy of a single intra-articular injection of autologous stromal vascular fraction (SVF) in dogs with chronic lameness due to advanced elbow osteoarthritis (OA) that were unresponsive to conventional drug therapy. In this clinical, prospective, non-blinded, single-center study, twenty-three dogs received autologous SVF derived from falciform adipose tissue. Primary outcome measures over the six-month study period included clinical-orthopedic and radiographic examinations, objective gait analysis and validated owner questionnaires. In 19 of 23 joints, no progression of OA was visible radiographically. Peak vertical force improved significantly at three months and vertical impulse at six months after the injection compared to baseline. Over 33% of dogs demonstrated treatment-related improvements in lameness based on objective gait analysis. Owner questionnaires indicated significant improvement in clinical signs throughout the study period and 26% of dogs showed treatment-related improvements in pain scores according to the Canine Brief Pain Inventory. No side effects were reported. These findings suggest that autologous regenerative cell therapy may provide a promising treatment option for dogs with advanced OA that do not respond to conventional drug therapy. However, the treatment did not improve the clinical symptoms in all dogs, so it cannot be recommended for all patients. Full article
(This article belongs to the Special Issue Use of Regenerative Therapies in Canine Osteoarthritis: Volume II)
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