Secondary Metabolites from Natural Sources: Mechanisms of Antimicrobial Action and Therapeutic Potential
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Plant-Derived Antibiotics".
Deadline for manuscript submissions: 31 July 2025 | Viewed by 25
Special Issue Editors
Interests: bioactive compounds; antitumor compounds; antimicrobial compounds; immunomodulation
Special Issues, Collections and Topics in MDPI journals
Interests: biomaterials with antimicrobial properties; infectious diseases; antimicrobial resistance mechanisms (ARM) and antimicrobial alternatives to ARM microorganisms; biofilms
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Secondary metabolites from natural sources play a pivotal role in the discovery of novel antimicrobial agents. These bioactive compounds, produced by plants, fungi, bacteria, and marine organisms, exhibit diverse mechanisms of action, including the disruption of microbial membranes, inhibition of critical metabolic pathways, and modulation of virulence factors. With the growing global challenge of antibiotic resistance, secondary metabolites present an invaluable resource for innovative therapeutic strategies.
Research into these natural compounds involves understanding their biosynthesis, structural diversity, and specific antimicrobial mechanisms. Equally important is evaluating their potential for safe therapeutic applications, including synergistic effects with existing antibiotics and overcoming resistance in multidrug-resistant pathogens.
This Special Issue will focus on advancements in the discovery, characterization, and therapeutic application of secondary metabolites with antimicrobial properties. Contributions in the form of original research articles, reviews, and communications exploring their mechanisms of action and clinical potential are highly encouraged.
Dr. Fatima Cerqueira
Dr. Maria Pia Ferraz
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- secondary metabolites
- bioactive compounds
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