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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Essential Oil of the Plants: Chemical Composition, Antimicrobial Activity, and Biological Applications

edited by

Luis Alberto Ortega-Ramirez

and

Jesus Fernando Ayala-Zavala

submission deadline 31 Mar 2025 | 8 articles | Viewed by 30256 | Submission Open

Keywords: natural compounds; antimicrobials; antibiofilms; antioxidants; antivirulence factors; mode of action; antiproliferative; citotoxicty

(This special issue belongs to the Section Plant-Derived Antibiotics)

Epidemiology and Mechanism of Bacterial Resistance to Antibiotics

edited by

Gabriela Loredana Popa

and

Mircea Ioan Popa

submission deadline 31 Mar 2025 | 7 articles | Viewed by 15661 | Submission Open

Keywords: multi-drug resistant (MDR); classic and molecular epidemiology; plasmids; resistance gene

Antimicrobial Resistance in Food Animals and Human — a One Health Perspective

edited by

Panagiota Gousia

and

Vangelis Economou

submission deadline 31 Mar 2025 | 5 articles | Viewed by 14426 | Submission Open

Keywords: antimicrobial resistance; multidrug resistance; food animals; One Health; zoonoses; resistance genes; food; foodborne pathogens; MRSA; VRE; carbapenemases; ESBL

Antimicrobial Resistance in Clinical Infection and Antibiotic Stewardship

edited by

Daniel T. Anderson

submission deadline 31 Mar 2025 | 5 articles | Viewed by 14338 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial resistance; treatment; antimicrobials

Life Defense in the New Century: Natural Products in the Development of New Antimicrobial Drugs

edited by

Matteo Micucci

submission deadline 31 Mar 2025 | 3 articles | Viewed by 8533 | Submission Open

Keywords: natural compounds; phytocomplexes; polyphenols; flavonoids; antibacterial; multitarget; nutraceuticals

(This special issue belongs to the Section Novel Antimicrobial Agents)

Editorial Board Members’ Collection Series: New Strategies to Overcome Antibiotic Resistance

edited by

Francesca Sisto

and

Simone Carradori

submission deadline 31 Mar 2025 | 3 articles | Viewed by 4641 | Submission Open

Keywords: antimicrobial resistance; biofilm; new targets; synthetic drugs; natural compounds; quorum sensing; in vivo models; checkerboard assay; resistance modifiers; probiotics

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Agents in Oral Diseases: Prophylaxis and Therapy between New and Old Molecules, 2nd Edition

edited by

Elena Varoni

submission deadline 31 Mar 2025 | 2 articles | Viewed by 3588 | Submission Open

Keywords: antibiotics; antiseptics; oral medicine; periodontology; oral infections

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

A Themed Issue in Honor of Professor Helen Giamarellou—Outstanding Contributions in the Fields of Antimicrobial Resistance and Difficult-to-Treat Resistance Pathogens

edited by Konstantinos Pontikis

submission deadline 31 Mar 2025 | 2 articles | Viewed by 2594 | Submission Open

Keywords: antibiotic stewardship; nosocomial infections; infection control; epidemiology of resistance plus in vitro investigation of underlying resistance mechanisms; infections in the ICU; neutropenic host infections; indicated therapeutic approach of MDR and XDR gram-negative infections; pharmacokinetics/pharmacodynamics of newer antimicrobial agents

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Advancements in the Control and Diagnosis of Antimicrobial Resistance in Infectious Diseases

edited by Soyoun Shin and

Alicia Galar

submission deadline 31 Mar 2025 | 2 articles | Viewed by 2415 | Submission Open

Keywords: infectious diseases; antimicrobial resistance; laboratory diagnostics

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial Agents in Prevention and Treatment of Oral Diseases

edited by

Sigrun Eick

submission deadline 31 Mar 2025 | 1 articles | Viewed by 1649 | Submission Open

Keywords: periodontitis; candidiasis; antibiotics; antiseptics; adverse effects; development of resistance

Climate Change and Antibiotic Resistance

edited by

Paola Di Carlo

submission deadline 31 Mar 2025 | Viewed by 836 | Submission Open

Keywords: climate change; antibiotic resistance; bacterial infections; global warming

Antibiotic Stewardship in Ambulatory Care Settings

edited by Mary Elizabeth Sexton and Sharon V. Tsay

submission deadline 31 Mar 2025 | 1 articles | Viewed by 804 | Submission Open

Keywords: ambulatory antimicrobial stewardship; antimicrobial resistance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Molecular Epidemiology and Antimicrobial Resistance Trends in Gram-Negative Bacteria and Mycobacterium tuberculosis

edited by

Karla Valéria Batista Lima

Yan Corrêa Rodrigues

and

Danielle Murici Brasiliense

submission deadline 31 Mar 2025 | Viewed by 341 | Submission Open

Keywords: antimicrobial resistance (AMR); gram-negative bacteria; mycobacterium tuberculosis; nontuberculous mycobacteria; molecular epidemiology; drug resistance mechanisms; virulence traits; carbapenem-resistant Enterobacterales; drug-resistant TB

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Innovative Antimicrobial Strategies to Combat Antibiotic Resistance

edited by

Chenxi Huang

and

Xiaohong Wang

submission deadline 31 Mar 2025 | Viewed by 245 | Submission Open

Keywords: nanotechnology applications; diagnostic strategies; phages-mediated strategies; foodborne pathogens; antibiotics; antimicrobial; multi-drug resistance; biocontrol

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotics in the Environment: Sources, Fate, and Mitigation Strategies

edited by Khaled Benis

submission deadline 31 Mar 2025 | Viewed by 243 | Submission Open

Keywords: antibiotic contamination; environmental fate; antibiotic resistance; mitigation strategies; pollution management

Biotechnological Production of Novel Antimicrobials

edited by

Vanja Vlajkov

Jovana Grahovac

and

Ivana Danilov

submission deadline 31 Mar 2025 | Viewed by 209 | Submission Open

Keywords: antibiotic resistance; biotechnology; antimicrobial activity; disease outbreak; pathogens; microorganisms; genetic engineering; artificial intelligence; optimisation; biocontrol

Fungal Metabolites and Synthetic Derivatives: Antimicrobial Properties Toward Microbial Pathogens

edited by João Vicente Braga De Souza

submission deadline 31 Mar 2025 | Viewed by 178 | Submission Open

Keywords: antimicrobial resistance; fungal metabolites; synthetic derivatives; antifungal agents; bioactive compounds

(This special issue belongs to the Section Fungi and Their Metabolites)

Antibiotics Use in Livestock and Poultry

edited by Ana L.P. Mateus

submission deadline 31 Mar 2025 | Viewed by 154 | Submission Open

Keywords: antimicrobial use; veterinary medical use; antimicrobial growth promotion; interventions; antimicrobial resistance; livestock; poultry

(This special issue belongs to the Section Antibiotics in Animal Health)

Microbial Natural Products as a Source of Novel Antimicrobials, 2nd Edition

edited by

Patricia Branco

and

Elisabete Muchagato Mauricio

submission deadline 5 Apr 2025 | 1 articles | Viewed by 430 | Submission Open

Keywords: antimicrobial peptides; mycocins; bacteriocins; antimicrobial activity; biopreservatives

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Stewardship in the Digital Age: The Role of Artificial Intelligence and Chatbots in Future Strategies

edited by

Alessandro Perrella

submission deadline 15 Apr 2025 | 2 articles | Viewed by 6399 | Submission Open

Keywords: AI; ChatGpt; AMS; AMR; infection; hospital aquired infection

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Rapid Antibiotic Susceptibility Testing

edited by Ahmad Salman and Itshak Lapidot

submission deadline 15 Apr 2025 | 2 articles | Viewed by 5024 | Submission Open

Keywords: bacterial infection; antibiotic; multi-drug resistance; bacterial susceptibility to antimicrobials; bacterial culturing; spectroscopy; machine learning

Antibiotic Resistance in Wastewater Treatment Plants

edited by Qingbin Yuan

submission deadline 15 Apr 2025 | 3 articles | Viewed by 2993 | Submission Open

Keywords: antibiotic resistance genes; wastewater treatment; one health; distribution and removal of ARGs; horizontal gene transfer

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Comprehensively Addressing Antimicrobial Resistance, Improving Food Safety and Achieving the One Health Goals: Global Challenges

edited by

Vladimir Kurćubić

, Pavle Mašković, Milan Mitić and

Nikola Stanišić

submission deadline 15 Apr 2025 | 2 articles | Viewed by 2969 | Submission Open

Keywords: antimicrobial resistance (AMR); food safety; foodborne pathogens; antibiotic residues; natural antimicrobials; one health

Antimicrobial Susceptibility of Veterinary Origin Bacteria

edited by Luchao Lv and Jing Wang

submission deadline 15 Apr 2025 | 1 articles | Viewed by 344 | Submission Open

Keywords: antimicrobial resistance; animal-derived resistant; antimicrobial-resistant bacteria; foodborne pathogens

(This special issue belongs to the Section Antibiotics in Animal Health)

Discovery and Synthesis of Antimicrobial Compounds Against Multidrug Resistance

edited by

Anita Cohen

submission deadline 15 Apr 2025 | Viewed by 206 | Submission Open

Keywords: antimicrobial resistance; medicinal chemistry; (pre)clinical development; intrinsic/synergistic activity; innovative antibiotic treatment; antimicrobial drug-candidate; new and repurposed medicines

(This special issue belongs to the Section Novel Antimicrobial Agents)

Nanotechnology-Based Antimicrobials and Drug Delivery Systems

edited by

Mihai Valentin Predoi

Simona Liliana Iconaru

and

Carmen Steluta Ciobanu

submission deadline 15 Apr 2025 | Viewed by 177 | Submission Open

Keywords: antimicrobial agents; nanocarriers; antimicrobial coatings; polymers nanocomposite; drug delivery systems

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobials Agents: Latest Advances and Prospects

edited by

Marius Stefan

submission deadline 20 Apr 2025 | 6 articles | Viewed by 13638 | Submission Open

Keywords: multidrug-resistant pathogens; infectious diseases; antibiotic resistance; new antimicrobials; drug development; antimicrobial activity; structure– activity relationship (SAR); antimicrobial therapy

(This special issue belongs to the Section Novel Antimicrobial Agents)

The Use of Antibiotics in Aquaculture: Antimicrobial Resistance, Efficacy and Safety, Ethical and Environmental Concerns

edited by

Øivind Bergh

submission deadline 20 Apr 2025 | 3 articles | Viewed by 4717 | Submission Open

Keywords: antibacterial agents; antimicrobial resistance; aquaculture

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Resistance and Zoonoses, 2nd Edition

edited by

Marina Spînu

and

Magdalena Rzewuska

submission deadline 20 Apr 2025 | 1 articles | Viewed by 1933 | Submission Open

Keywords: antibiotics; antimicrobial resistance; antimicrobial resistance genes; monitoring; one health; pathogen transmission; resistance mechanisms; surveillance; zoonotic pathogens; zoonosis

Infection Diagnostics and Antimicrobial Therapy for Critical Patient

edited by Giovanna Travi

submission deadline 30 Apr 2025 | 6 articles | Viewed by 23949 | Submission Open

Keywords: TDM (therapeutical drug monitoring); bacterials array; septic shock; MDR (multi drug resistance)

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Bacterial Detection, Identification, and Antimicrobial Susceptibility Testing

edited by

Gabriele Bianco

submission deadline 30 Apr 2025 | 7 articles | Viewed by 17779 | Submission Open

Keywords: identification methods; rapid diagnostics; MALDI-TOF MS; molecular testing; rapid antimicrobial susceptibility testing; antimicrobial susceptibility; synergy testing; β -lactam/β -lactamase inhibitor; fosfomycin; colistin

Antimicrobial and Anti-Infective Activity of Natural Products, 2nd Edition

edited by

Valério Monteiro-Neto

and

Elizabeth S. Fernandes

submission deadline 30 Apr 2025 | 12 articles | Viewed by 16997 | Submission Open

Keywords: antimicrobial activity; antivirulence activity; natural compounds and extracts; probiotics; Streptomyces spp. and other antibiotic-producing microorganisms; antimicrobial resistance inhibition; betalactamase inhibition; efflux pump inhibition; synergistic associations; models of infection; clinical assays

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antimicrobial Resistance in Animals and Animal Products and Its Environmental Transmission Aspects

edited by

Nikolaos Solomakos

Thomai Lazou

and

Andreana Pexara

submission deadline 30 Apr 2025 | 5 articles | Viewed by 9267 | Submission Open

Keywords: antimicrobial resistance; one health; AMR dissemination in the environment; antibiotics in animals; foodborne pathogens; animal products

(This special issue belongs to the Section Antibiotics in Animal Health)

Environmental Fate of Antibiotics: Monitoring, Toxicity, Resistance, and Removal Methods

edited by

Takashi Azuma

submission deadline 30 Apr 2025 | 4 articles | Viewed by 8677 | Submission Open

Keywords: antimicrobials; high-throughput analysis; wastewater treatment plant (WWTP); hospital wastewater; livestock environment; water purification plant (WTP); aquatic environment; environmental health risk assessment; antimicrobial resistance (AMR); advanced water treatment

The Spread of Antibiotic Resistance in Natural Environments

edited by

Daniel Gyamfi Amoako

submission deadline 30 Apr 2025 | 3 articles | Viewed by 6671 | Submission Open

Keywords: antibiotic resistance dissemination; antibiotic pollution; environmental adaptation; mobile genetic elements; ecological impact; environmental microbiome; resistance gene transfer; resistance hotspot; genomic landscape; One Health approach; emerging contaminants; bioinformatics in environmental genomics

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic Resistance: From the Bench to Patients, 2nd Edition

edited by

Fernando Albericio

and

Márió Gajdács

submission deadline 30 Apr 2025 | 2 articles | Viewed by 4192 | Submission Open

Keywords: antimicrobial resistance; infectious disease epidemiology; multidrug resistance; clinical bacteriology; antimicrobial stewardship; self-medication; knowledge– attitude– practice (KAP); regulatory perspectives; drug utilization; policy analysis; primary care; pharmacy; novel antimicrobial drugs; laboratory testing

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Innovations in Antibacterial Agents: Combating Resistance, Improving Efficacy and Exploring New Mechanisms

edited by

Rok Frlan

and

Martina Hrast

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3985 | Submission Open

Keywords: drug design; synthesis of novel antibacterial agents; computational chemistry; repurposing of drugs; novel antibacterial mechanisms

(This special issue belongs to the Section Novel Antimicrobial Agents)

Emerging Topics in Clostridioides difficile Infection: A One Health Problem

edited by

Simon D. Baines

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3640 | Submission Open

Keywords: clostridium difficile infection (CDI); antimicrobial resistance (AMR); antimicrobial prescribing; one health; laboratory studies

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Epidemiology, Antifungal Resistance and Therapy in Fungal Infection

edited by

Eduardo Alvarez Duarte

, Valentina Salas and Paulo Murilo Neufeld

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3531 | Submission Open

Keywords: epidemiology; antifungal agents; antifungal treatment; echinocandins; fluconazole; fungemia; microsatellite genotyping; yeast; antifungal resistance; aspergillosis; azole

Current Updates on Antimicrobial Resistance in Pediatric Patients, 2nd Edition

edited by Stefania Vergnano and

Corina Maria Vasile

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1937 | Submission Open

Keywords: antimicrobial resistance; inappropriate antibiotic use in pediatrics; public health; adverse effects of antibiotics; multidrug-resistant bacteria; future perspectives on antimicrobial resistance; role of antimicrobial resistance in pediatric patients

Antibiotic Resistance and the Responsible Use of Antibiotics in Human and Veterinary Medicine

edited by Horvat Olga and Frane Božić

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1696 | Submission Open

Keywords: antibiotics; antimicrobial resistance; human medicine; veterinary medicine; infection

Antibiotics Use and Antimicrobial Stewardship in Remote Areas—an One Health Perspective, 2nd Edition

edited by

Albert Figueras

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1612 | Submission Open

Keywords: antimicrobial consumption; antimicrobial stewardship; one-health; AWaRe classification; drug utilization studies; animal health; environmental health; human health; antimicrobial resistance; anthropological studies

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Resistance and Environmental Health, 2nd Edition

edited by

Akebe Luther King Abia

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1421 | Submission Open

Keywords: public health; environmental health; antibiotic resistance; environmental resistome; antibiotic-resistant bacteria; whole-genome sequencing; metagenomics; climate change and AMR; AMR models and One Health

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotics and Antimicrobial Resistance in Aquaculture: Alternative and Complementary Treatment Methods

edited by

Jaime Romero

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1306 | Submission Open

Keywords: antibiotics; antimicrobial resistance; alternatives; aquaculture; probiotics; phage therapy

Antimicrobial Activity of Plants Against Emerging or Drug-Resistant Human Pathogens

edited by

Andrés H. Uc-Cachón

and

Gloria María Molina-Salinas

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1108 | Submission Open

Keywords: anti-infective agents; antimicrobial activity; human pathogens; medicinal plants; natural products; phytodrugs

(This special issue belongs to the Section Plant-Derived Antibiotics)

Livestock Antibiotic Use and Resistance

edited by Valentina Monistero,

Paola Cremonesi

Gloria Gioia

and Valerio Bronzo

submission deadline 30 Apr 2025 | 2 articles | Viewed by 1040 | Submission Open

Keywords: farm; livestock; antibiotic; antimicrobial resistance; One Health; multidrug-resistant; methicillin-resistant; extended-spectrum beta-lactamase; carbapenemase; superbug

(This special issue belongs to the Section Antibiotics in Animal Health)

The Battle Against Urinary Tract Infections: The Role of Antibiotics

edited by

Pawel Miotla

and

Sara Wawrysiuk

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1036 | Submission Open

Keywords: urinary tract infection (UTI); antibiotics; antimicrobial resistance (AMR); multidrug-resistant uropathogens; antibiotic stewardship; UTI treatment; novel antibiotics; phage therapy; UTI pathogenesis; probiotics in UTI management

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Genetics and Antimicrobial Resistance in Pathogens of Hospital Importance

edited by

Maria de Lourdes R.S. Cunha

submission deadline 30 Apr 2025 | 1 articles | Viewed by 399 | Submission Open

Keywords: ESKAPEE pathogens; antimicrobial resistance; multidrug-resistant organisms; genetics; resistance mechanisms

(This special issue belongs to the Section Genetic and Biochemical Studies of Antibiotic Activity and Resistance)

Staphylococcus aureus Skin and Soft Tissue Infections Pathogenesis and Therapeutic Approaches, 2nd Edition

edited by

Marisa I. Gómez

Cintia González

and Constanza Giai

submission deadline 30 Apr 2025 | Viewed by 379 | Submission Open

Keywords: Staphylococcus aureus; pathogenesis; skin; skin and soft tissue infections; antimicrobial resistance; adaptation; host response

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Zoonotic Bacterial Infections: Genetic Studies and Antibiotic Resistance

edited by

Sónia Silva

Daniela Araújo

and

Joana Castro

submission deadline 30 Apr 2025 | Viewed by 302 | Submission Open

Keywords: zoonotic bacterial infections; transmission; public health; virulence factors; genetic studies; virulence factors; antibiotic resistance; clinical impact

(This special issue belongs to the Section Genetic and Biochemical Studies of Antibiotic Activity and Resistance)

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