Antibiotics Treatment in Helicobacter pylori Infection

A special issue of Antibiotics (ISSN 2079-6382).

Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 3411

Special Issue Editors


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Guest Editor
Department of Pharmacy, School of Medicine, University of Split, Split, Croatia
Interests: Helicobacter pylori infections; antimicrobial resistance; antimicrobial stewardship

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Guest Editor
Faculdade de Farmácia, Universidade de Lisboa, Lisbon, Portugal
Interests: Helicobacter pylori; antibiotic resistance; genomic analysis

Special Issue Information

Dear Colleagues,

The results of previously published research report that Helicobacter pylori infections have been reported in 50% of the general population, and even in 80% of people in less-developed countries. These proportions are high, and especially disturbing if we have in mind that this infection leads to gastric inflammation and consequently to peptic ulcer disease or even gastric carcinoma. Therefore, appropriate antibiotic treatment of Helicobacter pylori infection is crucial not only for gastric complications prevention in patients but also for the management of possible microbial drug resistance, recognized as an emerging public health care concern. Therefore, we aim to gather valuable data on infection management, antibiotic adverse drug reaction reports and initiatives to raise awareness of antibiotic resistance.

Dr. Josipa Bukić
Dr. Filipa F Vale
Guest Editors

Manuscript Submission Information

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Keywords

  • Helicobacter
  • antibiotics
  • adverse drug reaction
  • microbial drug resistance
  • antimicrobial stewardship

Published Papers (1 paper)

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Review

16 pages, 625 KiB  
Review
Personalized Approach in Eradication of Helicobacter pylori Infection
by Antonio Mestrovic, Nikola Perkovic, Ante Tonkic, Zeljko Sundov, Marko Kumric and Josko Bozic
Antibiotics 2023, 12(1), 7; https://doi.org/10.3390/antibiotics12010007 - 21 Dec 2022
Cited by 6 | Viewed by 3028
Abstract
The increase in antibiotic resistance to Helicobacter pylori (H. pylori) is associated with a decrease in the effectiveness of eradication therapy. Although some success has been achieved by adjusting therapeutic regimens according to local data on resistance to certain antibiotics, a [...] Read more.
The increase in antibiotic resistance to Helicobacter pylori (H. pylori) is associated with a decrease in the effectiveness of eradication therapy. Although some success has been achieved by adjusting therapeutic regimens according to local data on resistance to certain antibiotics, a new approach is needed to ensure a better therapeutic response. Tailored therapy, based on sensitivity tests to antibiotics, is increasingly proving to be a superior therapeutic option, even as a first-line therapy. Moreover, the recently published Maastricht VI guidelines emphasize utilizing a susceptibility-guided strategy in respect to antibiotic stewardship as the first choice for eradication therapy. In addition, polymerase chain reaction (PCR) technology is becoming a standard tool in the diagnosis of H. pylori infections through non-invasive testing, which further optimizes the eradication process. We provide a review regarding the current position of the individualized approach in eradication therapy and its future prospects. Based on novel understandings, the personalized approach is an effective strategy to increase the successful eradication of H. pylori infections. Full article
(This article belongs to the Special Issue Antibiotics Treatment in Helicobacter pylori Infection)
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