Optimization of Antibiotic Use in Hospitals: From Bedside to Theory
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotics Use and Antimicrobial Stewardship".
Deadline for manuscript submissions: closed (30 April 2023) | Viewed by 2896
Special Issue Editors
Interests: infectious disease; basic and clinic research in antimicrobial agents; diagnosis and treatment of drug-resistant bacterial infection; bacterial resistant surveillance and mechanisms; clinical pharmacology and rational use of antibiotics
Interests: infectious disease; pharmacokinetics/pharmacodynamics of antibiotics; bacterial infections and immunity
Special Issue Information
Dear Colleagues,
Antibiotics are the cornerstone of therapy for bacterial infections, especially for critically ill patients. Unreasonable use of antibiotics was associated with unfavorable outcomes, such as longer hospital stay, higher cost, and mortality. An appropriate antibiotic regimen is now recognized as one of the most important determinants of survival for patients with infections. However, rational regimens of antibiotics remain at a continuous exploration phase. Currently, pharmacokinetic/pharmacodynamic (PK/PD) is of value in establishing rational regimens of antibiotics in human. Thus, not only is early empiric antibiotic administration important but the optimization of those agents is crucial as well.
This Special Issue will center on optimization of antibiotic use in hospitals, and aims to optimize therapy in order to maximize efficacy and minimize side effects and emergence of resistance. It will focus on, but is not limited to, the choice of drug, right dosing, timing of treatments, PK/PD of antibiotics, management of special population, and novel models or technologies to determine the optimal regimens. The relationship between antibiotics uses and resistance in hospitalized patients are welcome as well.
Prof. Dr. Yonghong Xiao
Dr. Wei Yu
Guest Editors
Manuscript Submission Information
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Keywords
- antibiotics
- antimicrobials
- antibacterial mechanisms
- antibiotic resistance
- antimicrobial therapy
- antimicrobial stewardship
- pharmacokinetics/pharmacodynamics
- therapeutic model
- therapeutic drug monitor
- anti-infective
- clinical researches(trials) of infectious diseases
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