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Antibiotics
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Antimicrobial Agents in Oral Diseases: Prophylaxis and Therapy between New...
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Antimicrobial Agents in Oral Diseases: Prophylaxis and Therapy between New and Old Molecules, 2nd Edition

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotics Use and Antimicrobial Stewardship".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 1808

Special Issue Editor

Dr. Elena Varoni

E-Mail Website
Guest Editor
Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano, Milan, Italy
Interests: oral medicine; biomaterials; nutrition; oral health
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue carries on from the success of its predecessor, "Antimicrobial Agents in Oral Diseases: Prophylaxis and Therapy between New and Old Molecules", available at https://www.mdpi.com/journal/antibiotics/special_issues/antimicrobial_agents_oral.

As a continuation of this 2023 Special Issue, this edition will publish papers focusing on the management of oral diseases with a particular focus on the activity of old and new antiseptics and antibiotics, the use of these medications in the dental setting, and the education of dental professionals regarding accurate prescription.

Dr. Elena Varoni
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antibiotics
  • antiseptics
  • oral medicine
  • periodontology
  • oral infections

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Related Special Issue

Published Papers (2 papers)

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Research

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15 pages, 15950 KiB  
Article
In Vitro Inhibitory Effect of Silver Diamine Fluoride Combined with Potassium Iodide against Mixed-Species Biofilm Formation on Human Root Dentin
by Jutharat Manuschai, Maki Sotozono, Shoji Takenaka, Niraya Kornsombut, Ryouhei Takahashi, Rui Saito, Ryoko Nagata, Takako Ida and Yuichiro Noiri
Antibiotics 2024, 13(8), 743; https://doi.org/10.3390/antibiotics13080743 - 7 Aug 2024
Viewed by 643
Abstract
Applying a saturated potassium iodide (KI) solution immediately after silver diamine fluoride (SDF) application may affect the inhibitory effects of SDF on biofilm formation. This study compared the efficacy of 38% SDF with and without KI on preventing mixed-species biofilm formation on human [...] Read more.
Applying a saturated potassium iodide (KI) solution immediately after silver diamine fluoride (SDF) application may affect the inhibitory effects of SDF on biofilm formation. This study compared the efficacy of 38% SDF with and without KI on preventing mixed-species biofilm formation on human root dentin surfaces and assessed ion incorporation into root dentin. The biofilms, composed of Streptococcus mutans, Lactobacillus rhamnosus, and Actinomyces naeslundii, were grown on specimen surfaces treated with either SDF or SDF + KI. After 24 h, the biofilms were evaluated using scanning electron microscopy, live/dead staining, adenosine triphosphate (ATP) assays, colony-forming unit (CFU) counts, and quantitative polymerase chain reaction. A Mann–Whitney U test was used to compare the results between the groups. Ion incorporation was assessed using an electron probe microanalyzer. The relative ATP content in the SDF + KI group was significantly higher than that in the SDF group (p < 0.05). However, biofilm morphology and the logarithmic reduction in CFUs and bacterial DNA were comparable across the groups. The SDF + KI treatment resulted in less silver and fluoride ion incorporation than that yielded by SDF alone. The inhibitory effects of SDF and SDF + KI on mixed-species biofilm formation were almost equivalent, although KI application affected the ion incorporation. Full article
(This article belongs to the Special Issue Antimicrobial Agents in Oral Diseases: Prophylaxis and Therapy between New and Old Molecules, 2nd Edition)
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Review

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17 pages, 4262 KiB  
Review
Mapping Worldwide Antibiotic Use in Dental Practices: A Scoping Review
by Fatemeh Soleymani, Carlos Pérez-Albacete Martínez, Mehrdad Makiabadi and José Eduardo Maté Sánchez de Val
Antibiotics 2024, 13(9), 859; https://doi.org/10.3390/antibiotics13090859 - 8 Sep 2024
Viewed by 877
Abstract
Antibiotic resistance is a critical issue today, necessitating the monitoring of antibiotic usage across various sectors. To determine the defined daily doses (DDDs) of antibiotics prescribed by dentists globally, a comprehensive search was conducted in PubMed, ProQuest, ScienceDirect, Web of Science, Scopus, and [...] Read more.
Antibiotic resistance is a critical issue today, necessitating the monitoring of antibiotic usage across various sectors. To determine the defined daily doses (DDDs) of antibiotics prescribed by dentists globally, a comprehensive search was conducted in PubMed, ProQuest, ScienceDirect, Web of Science, Scopus, and EBSCOhost, resulting in the inclusion of 15 documents in this scoping review. The DDD per 1000 inhabitants per day (DID) for oral antibiotics prescribed by dentists for the studied countries was generally below 2.11, with the exception of South Korea, which had a DDD per 1000 patients per day (DPD) of less than 6.97. Most countries, except Croatia and Belgium, demonstrated a decreasing trend in DID before the COVID-19 pandemic, but restrictions during the pandemic led to an increase in these numbers. Penicillin-derived antibiotics were the most commonly prescribed antibiotic among dentists in most countries. This study highlights significant gaps and missing data regarding antibiotics prescribed by dentists worldwide. However, it also indicates that the publication of guidelines, education, and evaluation of antibiotic use can lead to more controlled and appropriate prescriptions among dental professionals. Full article
(This article belongs to the Special Issue Antimicrobial Agents in Oral Diseases: Prophylaxis and Therapy between New and Old Molecules, 2nd Edition)
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