Antibiotics Resistance in Gram-Negative Bacteria, 2nd Edition
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: 31 October 2024 | Viewed by 8206
Special Issue Editor
Interests: antibiotic resistance; molecular epidemiology of Gram-negative bacteria; antimicrobial effects of natural products on bacteria; antisense therapy; drug repositioning
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Antimicrobial resistance has been recognized as one of the most serious global threats to human health. The ability of Gram-negative bacteria to acquire resistance to antimicrobials via horizontal gene transfer and mutation is a real threat and a burden on human health and the economy. Even though they are most commonly detected in hospital settings, multi-drug-resistant Gram-negative bacteria have also been described in other ecological niches. The epidemiology of Gram-negative bacteria is complex and the importance of an integrated surveillance system based on the One-Health approach has been widely recognized. The use of antimicrobials in medicine, agriculture and livestock has favored the selection of these pathogens. In addition, increased hospitalization and the indiscriminate use of antimicrobials during the COVID-19 pandemic may have contributed to increased rates of multi-drug-resistant Gram-negative bacteria. Thus, the effects of antimicrobial resistance on public health and the economy in the short and medium term are concerning. Efforts must be taken to implement new policies and control programs on how to use and dispense antibiotics. Furthermore, understanding the resistance mechanisms and epidemiology of bacteria is critical for the development of novel antibacterials, which are needed to meet future demands. This Special Issue seeks manuscript submissions that further our understanding of the epidemiology and antimicrobial resistance of Gram-negative bacteria. Submissions on the search for new drugs developed through structural modification agents, the production of synthetic derivatives or repositioning are especially encouraged.
Prof. Dr. Simone Simionatto
Guest Editor
Manuscript Submission Information
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Keywords
- antimicrobial resistance
- epidemiology
- genomics surveillance
- One-Health
- enterobacteriaceae
- repurposing
- bacteriophages
- antimicrobial peptides
- natural compounds
- virulence profiles
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