Epidemiology and Antimicrobial Dosing Regimens in Intensive Care Units
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Pharmacokinetics and Pharmacodynamics of Drugs".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 1
Special Issue Editor
Interests: critical care; infections; sepsis; obesity; antibiotics; microdialysis; anesthesia; mechanical ventilation; electric impedance tomography
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In addition to the choice of antibiotic and the duration of therapy in intensive care medicine, the correct dosage is also crucial for the success of anti-infective therapy and the avoidance of resistance development. The pharmacological concept of antibiotic therapy is based on achieving a sufficiently adequate antibacterial effect at the site of the bacterial infection. Distribution as a pharmacokinetic process depends on the pharmacological properties of the substances as well as physiological conditions.
Various influencing factors such as hepatic or renal insufficiency and obesity, as well as the effects of severe infections, including sepsis and its course, influence the pharmacokinetics of antibiotics to varying degrees and often make it necessary to adjust the dose. Especially in intensive care medicine in the treatment of serious life-threatening infections, this presents physicians with ever new challenges.
Nowadays, there are various approaches to dosing antibiotics in intensive care medicine with differing evidence and sometimes controversial discussion.
This Special Issue, entitled ‘Epidemiology and Antimicrobial Dosing Regimens in Intensive Care Units’, aims to publish current epidemiological findings and new developments in the dosing of antibiotics in intensive care. This Special Issue welcomes various types of submissions, such as original research papers, short communications, reviews, case reports, and perspectives.
Prof. Dr. Philipp Simon
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- epidemiology
- critical care
- sepsis
- empiric therapy
- dosing
- interactions
- antibiotic resistance
- therapeutic drug monitoring
- pharmacokinetics/pharmacodynamics
- renal insufficiency
- renal replacement therapy
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
