Antibiotic Tolerance in Pseudomonas aeruginosa
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotics Use and Antimicrobial Stewardship".
Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 8103
Special Issue Editors
Interests: microbiology; infectious diseases; biofilm; mechanisms of antibiotic resistance and tolerance; quorum sensing
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Pseudomonas aeruginosa is an opportunistic pathogen commonly associated with chronic and refractory infections due to its ability to form biofilms. Antibiotic tolerance, which is regarded as the ability of bacteria to survive, but not grow, in the presence of antibiotics, has attracted attention as a cause of chronic infectious diseases. Antibiotic tolerance is a physiological condition that appears with a certain probability without any gene mutations. In biofilms, increasing the population of persister cells, which are dormant and nondividing, contributes to antibiotic tolerance. The elucidation of the molecular mechanisms responsible for antibiotic tolerance could lead to the discovery of potential targets for new antimicrobial agents.
The main objective of this Special Issue is to attract original research and review articles covering concepts and investigations regarding antibiotic tolerance. We hope that this Special Issue will also highlight new therapeutic strategies for P. aeruginosa chronic infections.
Prof. Dr. Keiji Murakami
Prof. Dr. Yukihiro Kaneko
Guest Editors
Manuscript Submission Information
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Keywords
- antibiotic tolerance
- biofilm
- chronic infection
- Pseudomonas aeruginosa
- antibiotics
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