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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The One Health Perspective: Unveiling Animal and Zoonotic Microbiota in the Frame of Antimicrobial Resistance

edited by

Athina S. Tzora

and

Chrysoula Voidarou

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1982 | Submission Open

Keywords: antimicrobial resistance (AMR); One Health approach; veterinary medicine; livestock production; foodborne pathogen reservoirs; epidemiological mapping; resistance mechanisms; microbiome; resistome; intervention

(This special issue belongs to the Section Antibiotics in Animal Health)

Antibiotics in Pathogen Control: From Infection to Antimicrobial Resistance

edited by

Alessia Catalano

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1836 | Submission Open

Keywords: resistance; pathogens; antimicrobials; ESKAPEE; One-Health; natural products

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Distribution, Sources and Risks of Bacteria and Their Antimicrobial Resistance Genes in the Environment, 2nd Edition

edited by Filip Gamoń,

Ewa Kotlarska

and Suparna Mitra

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1445 | Submission Open

Keywords: antimicrobial resistance (AMR) and One Health; AMR dissemination in the environment; risk assessment of AMR in environmental reservoirs (agroecosystems); antibiotic-resistant pathogenic and resident bacteria; antibiotic-resistance gene (ARG) transfer; ARG quantification; AMR and food/feed chain; antibiotics in animals; agrochemicals; antibiotic residues

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Managing Staphylococcus spp. Infections: Current Practices and Future Directions

edited by

Nikolaos Giormezis

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1231 | Submission Open

Keywords: Staphylococcus aureus; coagulase-negative staphylococci; novel antibiotics; novel therapies; bacteriophages; biofilm disruption

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotics in the Environment and Antimicrobial Resistance: A One Health Perspective

edited by

Marcelo Pedrosa Gomes

submission deadline 31 Dec 2026 | 1 articles | Viewed by 990 | Submission Open

Keywords: antibiotics; antimicrobial resistance; One Health; emerging contaminants; wastewater treatment; environmental monitoring; antibiotic resistance genes; ecotoxicology; aquatic environments

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Multidrug-Resistant Microorganisms: Overcoming the Challenges in Antibiotic Treatment

edited by Eleni E. Mylona and

Dimitris Kounatidis

submission deadline 31 Dec 2026 | 1 articles | Viewed by 643 | Submission Open

Keywords: multidrug-resistant; antibiotic treatment; MDR pathogens; therapeutic strategies

Feature Reviews in "Antimicrobial Peptides" 2026

edited by

Jean-Marc Sabatier

and

Gianfranco Bocchinfuso

submission deadline 31 Dec 2026 | Viewed by 479 | Submission Open

Keywords: antimicrobial peptides; innate immunity; host– pathogen interactions; antimicrobial resistance; peptide engineering; immunomodulation; microbial infections; microbiota; therapeutic development; drug design

(This special issue belongs to the Section Antimicrobial Peptides)

Diagnostics and Antimicrobial Treatment of Tuberculosis

edited by

Fabrizio Palmieri

Francesco Di Gennaro

and

Gina Gualano

submission deadline 31 Dec 2026 | 1 articles | Viewed by 440 | Submission Open

Keywords: Mycobacterium tuberculosis; molecular diagnostics; multidrug-resistant tuberculosis (MDR-TB); pharmacokinetics/pharmacodynamics; host-directed therapy; point-of-care testing; tuberculosis infection

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Bloodstream Infection: Current Challenges and Therapeutic Strategies

edited by

Daniel T. Anderson

and

Stefano Di Bella

submission deadline 31 Dec 2026 | 1 articles | Viewed by 439 | Submission Open

Keywords: bloodstream infection; antimicrobial stewardship; antimicrobial resistance

Antibiotic Susceptibility Testing Guides Clinical Treatment Decisions: From Empiric to Targeted Therapy

edited by

Jan Závora

, Simona Arientová and

Christopher K. C. Lai

submission deadline 31 Dec 2026 | Viewed by 350 | Submission Open

Keywords: antimicrobial susceptibility testing; antimicrobial resistance; empiric antimicrobial therapy; targeted antimicrobial therapy; clinical microbiology; infectious diseases; antimicrobial stewardship; infectious disease management; multidrug-resistant organisms

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Silent but Deadly: Insights into the Relationship Between Bacterial Dormancy and Antibiotic Tolerance

edited by

Massimiliano Lucidi

Marco Maria D'Andrea

and

Floriana Campanile

submission deadline 31 Dec 2026 | Viewed by 314 | Submission Open

Keywords: antibiotic persistence; antibiotic tolerance; viable but not culturable bacteria; bacterial quiescence; phenotypic heterogeneity; stress-induced dormancy; recalcitrant infection; recurrent infection; relapsing infection

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Pharmacokinetic and Antibiotic Dosing for Intensive Care Unit Patients, 2nd Edition

edited by

Yuhki Sato

submission deadline 31 Dec 2026 | Viewed by 272 | Submission Open

Keywords: antibiotics; pharmacokinetics– pharmacodynamics; therapeutic drug monitoring; population pharmacokinetics analysis; bacterial susceptibility

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics of Drugs)

Essential Oil of the Plants: Chemical Composition, Antimicrobial Activity, and Biological Applications, 2nd Edition

edited by

Luis Alberto Ortega-Ramirez

and

Jesús Fernando Ayala-Zavala

submission deadline 31 Dec 2026 | Viewed by 251 | Submission Open

Keywords: natural compounds; antimicrobials; antibiofilms; antioxidants; antivirulence factors; mode of action; antiproliferative; citotoxicty

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antibiotics and Environment—Research and Development Toward the One Health Approach, 2nd Edition

edited by

Takashi Azuma

submission deadline 31 Dec 2026 | Viewed by 250 | Submission Open

Keywords: antimicrobial resistance (AMR); antimicrobials; water purification plant (WTP); wastewater treatment plant (WWTP); hospital wastewater; livestock environment; aquaculture farm environment; aquatic environment

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Monitoring Antibiotic Use in Healthcare Settings: Trends, Stewardship, and Resistance Prevention

edited by Hao-Yuan Lee

submission deadline 31 Dec 2026 | Viewed by 220 | Submission Open

Keywords: antibiotic use; antimicrobial stewardship; healthcare settings; antimicrobial resistance; prescription trends; infection control; resistance prevention; drug utilization monitoring

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Diabetic Foot Infection and Clinical Infections: New Insights in Diagnosis and Treatment

edited by

Francisco Javier Álvaro-Afonso

submission deadline 31 Dec 2026 | Viewed by 217 | Submission Open

Keywords: diabetic foot infection; clinical infections; osteomyelitis; antimicrobial therapy; diagnostic imaging; artificial intelligence in infection care; microbiology; wound management; multidisciplinary care; infection prevention

Combating Antimicrobial Resistance Through the One Health Approach

edited by

and

submission deadline 31 Dec 2026 | Viewed by 214 | Submission Open

Keywords: antimicrobial resistance; One Health; environmental AMR; antibiotic resistance genes

The Emerging Threat of Drug Resistance in Fungal Pathogens: Challenges and Management

edited by

Anil Mathew Tharappel

submission deadline 31 Dec 2026 | Viewed by 198 | Submission Open

Keywords: drug resistance; antifungal; fungal diseases; aspergillosis; cryptococcosis; candidiasis

(This special issue belongs to the Section Fungi and Their Metabolites)

Feature Reviews in "Novel Antimicrobial Agents" 2026

edited by

Carlos M. Franco

submission deadline 31 Dec 2026 | Viewed by 192 | Submission Open

Keywords: antimicrobial agents; antimicrobial agents resistance; therapeutic opportunities; review

(This special issue belongs to the Section Novel Antimicrobial Agents)

Feature Review in "Antibiotics in Animal Health" Section 2026

edited by

Yongzhen Ding

and

Fengxia Yang

submission deadline 31 Dec 2026 | Viewed by 132 | Submission Open

Keywords: antibiotic resistance; animal health; one health; zoonotic transmission

(This special issue belongs to the Section Antibiotics in Animal Health)

Plant Natural Products as Antibacterial and Antifungal Agents for Agricultural Applications

edited by

Janet María León-Morales

, Fidel Martínez-Gutiérrez and

Martha Adriana Leyte-Lugo

submission deadline 31 Dec 2026 | Viewed by 132 | Submission Open

Keywords: plant-derived antimicrobials; phytopathogens; mycotoxins; antifungal and antibacterial activities; secondary metabolites; post-harvest diseases management

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antimicrobial and Anti-Infective Activity of Natural Products, 3rd Edition

edited by

Valério Monteiro-Neto

and

Elizabeth S. Fernandes

submission deadline 31 Dec 2026 | Viewed by 131 | Submission Open

Keywords: antibiotic-producing microorganisms; antimicrobial activity; antimicrobial resistance; antivirulence therapy; beta-lactamase inhibition; clinical evaluation; drug synergism; efflux pump inhibitors; infection models; mechanism of action; natural products; Streptomyces spp.

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antibiotic Adjuvants for Overcoming and Preventing Antimicrobial Resistance

edited by

Marta Krychowiak-Maśnicka

submission deadline 31 Dec 2026 | Viewed by 126 | Submission Open

Keywords: antibiotic adjuvants; antimicrobial resistance; resistance-modifying agents; drug repurposing; biofilm-associated resistance; efflux pump inhibitors; antibiotic synergy; intrinsic resistance

(This special issue belongs to the Section Novel Antimicrobial Agents)

Surveillance and Mitigation of Antimicrobial Resistance Across the Food Chain

edited by María Virginia Zbrun and

Ana Inés Molineri

submission deadline 31 Dec 2026 | Viewed by 115 | Submission Open

Keywords: one health; epidemiology; food chain; antimicrobial resistance

(This special issue belongs to the Section Antibiotics in Animal Health)

Clostridioides difficile Infection and Pathogenesis

edited by

Katarína Čurová

, Martin Novotný and Pavol Jarčuška

submission deadline 31 Dec 2026 | Viewed by 77 | Submission Open

Keywords: Clostridioides difficile; Clostridioides difficile infection (CDI); pathogenesis; virulence factors; antibiotic resistance; treatment

Monitoring the Dissemination of Antibiotic Resistance in Environments

edited by Ludovica Rolando and

Tanita Pescatore

submission deadline 31 Dec 2026 | Viewed by 65 | Submission Open

Keywords: antibiotic-resistant bacteria; antibiotic resistance genes; multiresistance; environmental ARG spread; co selection; cross-resistance; resistome; environmental monitoring; mitigation strategies; natural antibiotic resistance

Natural and Biological Delivery Systems for Antibiotics and Antifungal Agents

edited by

Sabine Berteina-Raboin

submission deadline 31 Dec 2026 | Viewed by 58 | Submission Open

Keywords: natural and/or biological carrier; antibiotics; antifungals; bioavailability; cellular penetration

(This special issue belongs to the Section Antibiofilm Strategies)

Commemorative Issue of Linezolid: 30 Years Combating Multidrug Resistance—What Do We Know About the Past, and What Does the Future Hold?

edited by

Piera Anna Martino

submission deadline 31 Dec 2026 | Viewed by 55 | Submission Open

Keywords: linezolid; gram positive bacterial infections; antimicrobial resistance; genotyping; NGS; alternatives drugs

(This special issue belongs to the Section Novel Antimicrobial Agents)

A Themed Issue in Honor of Professor Matthew E. Falagas: Antimicrobial Resistance and the Treatment of Complex Infections

edited by

Drosos E. Karageorgopoulos

submission deadline 15 Jan 2027 | 1 articles | Viewed by 1783 | Submission Open

Keywords: Acinetobacter baumannii; antimicrobial resistance; aztreonam– avibactam; carbapenemase; cefiderocol; colistin; Enterobacterales; fosfomycin; Klebsiella pneumonia; metallo β -lactamase; Pseudomonas aeruginosa

Current Challenges in Antimicrobial Stewardship

edited by

Andreas A. Von Ameln-Mayerhofer

submission deadline 30 Jan 2027 | 2 articles | Viewed by 2486 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial resistance; antibiotics prescribing; intervention; irrational prescriptions; surveillance; therapeutic monitoring; ABS; AMS; antibiotic stewardship; best practice; interprofessional; rational prescribing; DDD/100; RDD/100

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Metal-Based Complexes as Novel Antimicrobial Strategies

edited by

Alberto Aragón-Muriel

Dorian Polo Cerón

and

David Morales-Morales

submission deadline 31 Jan 2027 | 1 articles | Viewed by 9885 | Submission Open

Keywords: antibiotics; metal-based complexes; antimicrobial resistance; antimicrobial therapy; drug design; bioinorganic; metallodrug; metallopharmaceutical

(This special issue belongs to the Section Novel Antimicrobial Agents)

Strategies for the Design of Hybrid-Based Antimicrobial Compounds

edited by

Vuyolwethu Khwaza

Sibusiso Alven

and

Blessing Atim Aderibigbe

submission deadline 31 Jan 2027 | 4 articles | Viewed by 7199 | Submission Open

Keywords: hybrid compounds; antimicrobial agents; antibacterial agents; antifungal activity; antiviral activity; in vitro evaluation; structure– activity relationship (SAR); bioactive molecules; nanoformulations; targeted drug delivery; pharmacological screening; clinical studies

(This special issue belongs to the Section Novel Antimicrobial Agents)

A Themed Issue in Honor of Prof. Dr. Rob Capon—Outstanding Contributions in the Field of Anti-Infectives

edited by Mark Butler

submission deadline 31 Jan 2027 | 2 articles | Viewed by 5175 | Submission Open

Keywords: natural product; microorganism; bacteria; fungi; marine antibiotic; antibacterial; antheminthic; crop protection

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Resistance and Intervention Strategies in Intestinal Pathogens: A One Health Approach

edited by Gaetano Iaquinto

submission deadline 31 Jan 2027 | 1 articles | Viewed by 3864 | Submission Open

Keywords: epidemiology; antimicrobial resistance; multi-drug resistance; immunomodulatory activity; cytokines; gut microbiota; new antibiotics research; new vaccines; faecal microbiota transplantation; infection prevention

Antimicrobial Peptides (AMPs) Against Human Pathogens

edited by

Pedro Souza

submission deadline 31 Jan 2027 | 2 articles | Viewed by 2128 | Submission Open

Keywords: antimicrobial peptides (AMPs); mechanisms; structure– function relationships; synthetic and bioengineered peptides

(This special issue belongs to the Section Antimicrobial Peptides)

Antibiotic Use and the Emergence of Antibiotic Resistance in Clinical Settings, 2nd Edition

edited by

Aleksandra Barac

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1847 | Submission Open

Keywords: antibiotic use; antibiotic resistance; clinical settings; clinical infections; mechanisms underlying the development of resistance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Rethinking Mild Infections: The Role of Natural Products in Antimicrobial Stewardship

edited by

Karel Kostev

submission deadline 31 Jan 2027 | 2 articles | Viewed by 1831 | Submission Open

Keywords: natural products; herbal products; phytopharmaceutical; antimicrobial resistance; respiratory tract infections; urinary tract infections

Molecular Epidemiology and Antibiotic Resistance in MRSA: Recent Advances in Surveillance and Control

edited by

Jae-Seok Kim

submission deadline 31 Jan 2027 | 1 articles | Viewed by 1703 | Submission Open

Keywords: Staphylococcus aureus; methicillin-resistant S. aureus (MRSA); hospital-associated MRSA (HA-MRSA); antimicrobial resistance; molecular epidemiology; evolution of resistance; surveillance

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial Resistance in Bacterial Pathogens: Surveillance, Mechanisms, and Diagnostics

edited by Mariela E. Srednik

submission deadline 31 Jan 2027 | 1 articles | Viewed by 463 | Submission Open

Keywords: antimicrobial resistance; bacterial pathogens; surveillance; diagnostics

Clostridioides difficile Infection: Pathogenesis, Antibiotic Resistance, and Therapeutic Advances

edited by

Yongrong Zhang

submission deadline 31 Jan 2027 | Viewed by 406 | Submission Open

Keywords: Clostridioides difficile; infection; recurrence; antibiotic resistance; therapeutics; pathogenesis

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic Therapies for Multidrug-Resistant Infections

edited by

Antonio Riccardo Buonomo

submission deadline 31 Jan 2027 | Viewed by 299 | Submission Open

Keywords: MDR; gram-negative infections; acinteobacter baumannii; stenotrophomonas maltophilia; KPC; MBL

Plant-Derived Nanoantibiotics: Innovations and Applications

edited by

Luciano Paulino Silva

submission deadline 31 Jan 2027 | Viewed by 264 | Submission Open

Keywords: nanotechnology; plant-derived antibiotics; nanoparticles; antimicrobial resistance; green synthesis; drug delivery; nano-formulations; bioactive compounds; nanoantibiotics

Antibiotic Resistance in Africa: Epidemiology, Genomic Surveillance, and One Health Solutions

edited by

Bassam Elgamoudi

submission deadline 31 Jan 2027 | Viewed by 118 | Submission Open

Keywords: antimicrobial resistance; antibiotic resistance; Africa; genomic surveillance; molecular epidemiology; antimicrobial stewardship; resistant pathogens; infectious diseases; AMR surveillance

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Food-Borne Pathogens and Antimicrobial Resistance, 2nd Edition

edited by

Carlos M. Franco

and

Adrian Olariu-Jurca

submission deadline 31 Jan 2027 | Viewed by 83 | Submission Open

Keywords: foodborne pathogens; antibiotic susceptibility; molecular epidemiology investigations; new generation antibiotic agents; horizontal gene transfer; whole genome sequencing

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Plant Secondary Metabolites Targeting Biofilms and Antibiotic Resistance

edited by

Nilofar Nilofar

submission deadline 31 Jan 2027 | Viewed by 9 | Submission Open

Keywords: plant secondary metabolites; antibacterial; biofilms; antioxidant; antibiotic-resistance; phenolics; flavonoids

(This special issue belongs to the Section Plant-Derived Antibiotics)

Essential Oils as Natural Antimicrobials: Extraction, Characterization, and Synergistic Applications

edited by

Sergio A. Rodríguez

, Axel Hollmann and

Douglas Siqueira de Almeida Chaves

submission deadline 28 Feb 2027 | 2 articles | Viewed by 3934 | Submission Open

Keywords: natural antimicrobials; biofilm eradication; mechanism of action; synergism; antagonism; cytotoxicity; compound isolation; membrane interaction; enzymatic inhibition; DNA interaction; oxidative stress

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antimicrobial Resistance and Prevalence of Pathogens in Tropical and Endemic Regions: Surveillance, Diagnostics, and Therapeutic Strategies

edited by

Ramón Pérez-Tanoira

submission deadline 28 Feb 2027 | Viewed by 121 | Submission Open

Keywords: antimicrobial resistance; tropical regions; pathogen prevalence; epidemiological surveillance; One Health; biofilms; carbapenemase-producing Enterobacteriaceae; multidrug-resistant Pseudomonas aeruginosa; gastrointestinal infections; neglected tropical diseases

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial Stewardship and Infection Prevention in Intensive Care Units—2nd Edition

edited by

Mihai Sava

submission deadline 28 Feb 2027 | Viewed by 70 | Submission Open

Keywords: antimicrobial stewardship; infection prevention; intensive care unit (ICU); antimicrobial resistance; healthcare-associated infections; patient safety

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Phages vs. Antibiotics in the Age of Resistance

edited by

Jean Pierre González-Gómez

submission deadline 28 Feb 2027 | Viewed by 58 | Submission Open

Keywords: bacteriophages; antimicrobial resistance; phage therapy; multidrug-resistant bacteria; One Health; alternative antimicrobials

(This special issue belongs to the Section Bacteriophages)

Antibiotics in the Environment: Sources, Fate, and Mitigation Strategies, 2nd Edition

edited by Khaled Benis

submission deadline 25 Mar 2027 | Viewed by 108 | Submission Open

Keywords: antibiotic contamination; environmental fate; antibiotic resistance; mitigation strategies; pollution management

Displaying special issue 301-350 on page 7 of 8.

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