Special Issues

Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Role of Oxidative Stress in Environmental Toxicity—2nd Edition
edited by Hariz Islas Flores
submission deadline 10 Dec 2025 | 1 articles | Viewed by 2054 | Submission Open
Keywords: environmental pollutants; oxidative stress biomarkers; water/air/soil pollution; environmental toxicity; ROS and RNS
Phenolics as Antioxidant Agents—2nd Edition
edited by
submission deadline 10 Dec 2025 | Viewed by 156 | Submission Open
Keywords: antioxidants; bioactive compounds; oxidative stress; structure– activity relationships (SARs); sustainable extraction; green chemistry; therapeutic potential; in vitro and in vivo models; food and biomedical applications
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Redox Regulation in Algae
edited by
submission deadline 10 Dec 2025 | Viewed by 105 | Submission Open
Keywords: algae; reactive oxygen species; redox regulation; stress responses; NADPH oxidases; antioxidants; redox-sensitive transcription factors
(This special issue belongs to the Section ROS, RNS and RSS)
Applications of Antioxidant Nanoparticles, 2nd Edition submission deadline 15 Dec 2025 | 9 articles | Viewed by 21172 | Submission Open
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Harnessing Antioxidants: Pioneering Approaches in Cardiovascular Disease Prevention and Therapy
edited by and
submission deadline 15 Dec 2025 | 1 articles | Viewed by 2754 | Submission Open
Keywords: oxidative stress; reactive oxygen species (ROS); antioxidants; cardiovascular diseases
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Phytochemical Analysis and Evaluation of Antioxidant Properties in Medicinal Plants submission deadline 20 Dec 2025 | 7 articles | Viewed by 21664 | Submission Open
Keywords: antioxidant activity; phytochemicals in plants; medicinal plants; extraction; in vivo analysis; in vitro analysis
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Interplay of Microbiome and Oxidative Stress submission deadline 20 Dec 2025 | 3 articles | Viewed by 12147 | Submission Open
Keywords: microbiome; oxidative stress; antioxidants; gut microbiota; free radicals; reactive oxygen species; gut– brain axis; dysbiosis; microbial metabolites; mitochondrial function; probiotics; microbe– host interactions
Antioxidant and Anti-Inflammatory Properties of Mushrooms: From Structure to Functionality
edited by
submission deadline 20 Dec 2025 | 3 articles | Viewed by 11953 | Submission Open
Keywords: mushroom; antioxidants; metabolic syndrome; functional food; nutraceuticals; polysaccharides; phenolics; terpenoids
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
The Use of Antioxidant-Rich Foods and Supplements in Disease Prevention submission deadline 20 Dec 2025 | 3 articles | Viewed by 9678 | Submission Open
Keywords: dietary antioxidants; bioactivity; metabolomics; human diet; xenobiotics; polyphenols; vitamins; health promotion
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Significance of Antioxidant Mechanisms in Intestinal Inflammation—2nd Edition submission deadline 20 Dec 2025 | 1 articles | Viewed by 717 | Submission Open
Keywords: antioxidant therapy; antioxidants; intestinal inflammation; oxidative stress; polyphenol; reactive oxygen/nitrogen species; redox homeostasis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Advances in Plant Redox Biology Research
edited by Yurong Xie and Ming Chang
submission deadline 20 Dec 2025 | Viewed by 240 | Submission Open
Keywords: plant redox biology; reactive oxygen species; reactive nitrogen species; plant development; environmental stress; abiotic/biotic stresses; host– microbe interactions
(This special issue belongs to the Section ROS, RNS and RSS)
Antioxidants as Adjuvants for Inflammatory Bowel Disease Treatment submission deadline 22 Dec 2025 | 4 articles | Viewed by 9317 | Submission Open
Keywords: IBD; antioxidant; gut barrier; inflammation; natural compounds; microbiome; colon cancer; adjuvant; nutritional bioactive products; polyphenols
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Hydrogen and Oxidative Stress: Implications for Health and Longevity
edited by and
submission deadline 25 Dec 2025 | 2 articles | Viewed by 1919 | Submission Open
Keywords: molecular hydrogen (H2); oxidative stress; redox homeostasis; selective antioxidant; reactive oxygen species (ROS); aging and longevity; mitochondrial protection; cellular resilience; hydrogen therapy; inflammation and immunity; neurodegeneration; cardiovascular health; metabolic disorders; gene regulation; translational medicine; longevity
(This special issue belongs to the Section ROS, RNS and RSS)
Nitric Oxide and Redox Mechanisms
edited by , Paolo Ascenzi and
submission deadline 30 Dec 2025 | 6 articles | Viewed by 13961 | Submission Open
Keywords: nitric oxide; ROS and RNS; nitrosative stress; NO signaling; redox mechanisms
(This special issue belongs to the Section ROS, RNS and RSS)
Antioxidant Response in Aquatic Animals
edited by Martha Gabriela Gaxiola-Cortes
submission deadline 30 Dec 2025 | 9 articles | Viewed by 13420 | Submission Open
Keywords: antioxidant system; respiration; nutrition; culture; fish; aquatic animals; reactive oxygen species (ROS); superoxide dismutase (SOD)
Antioxidant and Anti-Inflammatory Potential of Plants in Cancer Treatment submission deadline 30 Dec 2025 | 3 articles | Viewed by 7512 | Submission Open
Keywords: phytochemical characterization; antioxidant and anti-inflammatory natural compounds and extracts; natural waste resources; horticultural or wild plants; medicinal plants; and edible plants; green selective extraction processes
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Lipid Peroxidation and Cancer submission deadline 30 Dec 2025 | 1 articles | Viewed by 760 | Submission Open
Keywords: lipid peroxidation; fatty acid metabolism; 4-hydroxynonenal (HNE); malondialdehyde (MDA); ferroptosis; carcinogenesis; cancer progression
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Male Reproductive Health submission deadline 31 Dec 2025 | 10 articles | Viewed by 30625 | Submission Open
Keywords: oxidative stress; antioxidant therapy; male reproductive health; male fertility; erectile dysfunction; prostatic disease; male ageing
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Therapies in Cardiovascular, Cardiorenal and Metabolic Diseases
edited by Kaushik P. Patel, Hong Zheng and
submission deadline 31 Dec 2025 | 5 articles | Viewed by 19079 | Submission Open
Keywords: antioxidant therapies; oxidative stress; cardiovascular diseases; cardiorenal diseases; metabolic diseases
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Carotenoids in Health and Disease
edited by Kazutoshi Shindo
submission deadline 31 Dec 2025 | 3 articles | Viewed by 11810 | Submission Open
Keywords: antioxidant activities of carotenoids; analytical chemistry on carotenoids; reactive oxygen species (ROS) and disease; production of carotenoids
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Multi-Target Profile of Antioxidant Compounds, Including Repurposing and Combination Strategies—2nd Edition
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 9920 | Submission Open
Keywords: polypharmacology; multi-target ligands; rational drug; design repurposing; off-target effects; computational techniques
Agri-Food Wastes as Natural Source of Bioactive Antioxidants: Fourth Edition submission deadline 31 Dec 2025 | 4 articles | Viewed by 9747 | Submission Open
Keywords: agri-food by-products; agri-food waste; nutraceuticals; functional foods; cosmeceutical products; sustainable practices; bioactive compounds; health effects
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Redox Regulation in Cardiovascular Diseases submission deadline 31 Dec 2025 | 3 articles | Viewed by 9047 | Submission Open
Keywords: oxidative stress; mitochondria; metabolism; chronic inflammation; atherosclerosis; CVD; ROS
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Selected Papers from the 2nd International Electronic Conference on Antioxidants (IECAN2025) submission deadline 31 Dec 2025 | 2 articles | Viewed by 7666 | Submission Open
Keywords: obesity; cardiovascular diseases; chronic disease; dietary prevention; antioxidants intake; gut microbiome; natural and synthetic antioxidants; antioxidant enzyme systems; antioxidant extraction
Oxidative Stress, Antioxidants, and Mechanisms in FLASH Radiotherapy submission deadline 31 Dec 2025 | 4 articles | Viewed by 7129 | Submission Open
Keywords: radiobiology and radiotherapy; ultra-high dose rate irradiation and the FLASH effect; molecular and cellular mechanisms; radiation-induced oxidative stress; reactive oxygen and nitrogen species; inflammatory processes; antioxidants and radioprotectors; pulse radiolysis; kinetics; physicochemical and biological processes; DNA damage; role of oxygen and the oxygen depletion hypothesis; modeling and experimental; FLASH particle therapy
Role of Reactive Oxygen Species (ROS) in Tumor Microenvironment Modulation submission deadline 31 Dec 2025 | 3 articles | Viewed by 6711 | Submission Open
Keywords: reactive oxygen species; tumor microenvironment; stroma cells; functional genomics; spatial transcriptomics; single-cell sequencing; RNA-seq; cancer; diagnosis and prognosis; biomarkers
Antioxidant Activity of Polyphenolic Extracts
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 6615 | Submission Open
Keywords: antioxidant activity; polyphenols; plant extracts; oxidative stress
Oxidative Stress in Rare Diseases: Mechanisms, Implications, and Therapeutic Opportunities submission deadline 31 Dec 2025 | 2 articles | Viewed by 5549 | Submission Open
Keywords: rare diseases; oxidative stress; free radicals; biomedicine; redox biomarkers; redox epigenetics; redox metabolism; redox control of protein function; ferroptosis
Redox Biology and Genomic Integrity
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 5154 | Submission Open
Keywords: redox biology; reactive oxygen species (ROS); oxidative stress; oxidative DNA damage; genome stability; DNA repair; hypermutation; antioxidant defense mechanisms; mitochondrial dysfunction; Saccharomyces cerevisiae; cellular adaptation; epigenetics; telomeres
Natural Antioxidants in Animal Nutrition
edited by , , Chao Wang, Hao Zhang and Jingfei Zhang
submission deadline 31 Dec 2025 | 3 articles | Viewed by 5041 | Submission Open
Keywords: antioxidants; animal; growth; metabolism; nutrition; oxidative stress; plant extracts
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
From Field to Cell: Redox Mechanisms of Chemical Stressor Toxicity in Biological Systems submission deadline 31 Dec 2025 | 1 articles | Viewed by 3360 | Submission Open
Keywords: redox biology; environmental toxicology; chemical stressors; pesticides; redox signaling
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Editorial Board Members’ Collection Series: Advances in Redox-Tools and Therapies in Cardiovascular Disease submission deadline 31 Dec 2025 | 2 articles | Viewed by 2927 | Submission Open
Keywords: cardiovascular disease; oxidative stress; inflammation; reactive oxygen species; redox signalling
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Metabolic Dysfunction and Oxidative Stress submission deadline 31 Dec 2025 | 2 articles | Viewed by 2768 | Submission Open
Keywords: iron; mitochondria; oxidative stress; inflammation; metabolism; free radicals
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress in Respiratory Disorders
edited by
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2525 | Submission Open
Keywords: oxidative stress; lung; reactive oxygen species; reactive nitrogen species; acute lung injury; asthma; COPD; lung fibrosis; pulmonary silicosis; premature neonate
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Novel Strategies for Oxidative Stress Management: Dietary Interventions for Liver and Gut Health
edited by and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 2305 | Submission Open
Keywords: antioxidant compounds; phytochemicals; dietary interventions; hepatic disease; intestinal disease; redox homeostasis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Radiation Exposure and Health: The Role of Oxidative Stress and Inflammatory Response submission deadline 31 Dec 2025 | 2 articles | Viewed by 1595 | Submission Open
Keywords: radiation; inflammatory response; oxidative stress
Super Oxide Dismutase (SOD) Isoenzymes and Reactive Oxygen Species (ROS) in Immuno-Pathophysiology
edited by Giuseppina Ruggiero and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1501 | Submission Open
Keywords: superoxide dismutase (SOD) isoenzymes; superoxide dismutase (SOD)1; cell signalling; cell metabolism; cell functions; cellular stress; disease pathogenesis
Natural Antioxidants in Functional Foods
edited by , Palmira De Bellis and
submission deadline 31 Dec 2025 | 2 articles | Viewed by 1445 | Submission Open
Keywords: polyphenols; functional foods; fermentation; antioxidant activity; anti-inflammatory activity
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Modulation of Biochemical, Cellular and Physiological Mechanisms in Response to Oxidative Stress in Animals submission deadline 31 Dec 2025 | 1 articles | Viewed by 1126 | Submission Open
Keywords: animals; cell signaling; metabolism; cell death responses; oxidative damage
Algal Antioxidants: Physiology, Metabolism, and Evolution
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 802 | Submission Open
Keywords: algae; antioxidant; oxidative stresses; algal physiology
Emerging Trends in Antioxidant Nutraceuticals submission deadline 31 Dec 2025 | 1 articles | Viewed by 606 | Submission Open
Keywords: nutraceuticals; diabetes; cancer; oxidative stress; inflammation; antioxidant
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Phenolic Antioxidants in Functional Foods and Nutraceuticals submission deadline 31 Dec 2025 | Viewed by 497 | Submission Open
Keywords: bioactive compounds; agri-food byproducts; in vitro assays; in vivo studies; green extraction; biological activities; safety assessment; industrial application
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Antioxidants and Dietary Nutrition: Emerging Trends, and Clinical Applications submission deadline 31 Dec 2025 | Viewed by 445 | Submission Open
Keywords: antioxidants; oxidative stress; chronic disease prevention; dietary strategies; bioavailability
Antioxidant Properties of Functional Foods
edited by Konstantinos G. Adamopoulos and
submission deadline 31 Dec 2025 | Viewed by 427 | Submission Open
Keywords: antioxidant; extraction; bioavailability; processing; optimization; functional food; phytochemicals
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Metabolism and Epigenetics: A Potential Dual Interaction in the Microenvironment of Solid Tumors
edited by , , and Sebastiano Giallongo
submission deadline 31 Dec 2025 | Viewed by 318 | Submission Open
Keywords: metabolomics; tumor cell metabolism; tumor microenvironment; cell communication; cell signaling; epigenetics; post-translational modifications; cancer therapy
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
The Role of Dietary Antioxidants in Alleviating Oxidative Stress and Inflammation for Enhanced Immunity in Animals
edited by Yanka D. Karamalakova and
submission deadline 31 Dec 2025 | Viewed by 301 | Submission Open
Keywords: antioxidants; antioxidant feeding; insect meal; growth performance; digestible energy; nutrient digestibility; blood biochemistry; oxidative stress (OS); lipid peroxidation (MDA); ROS/RNS; superoxide dismutase (SOD); catalase (CAT); glutathione (GSH); glutathione peroxidase (GPx); inflammation markers; total antioxidant capacity (TAC); meat; milk; eggs quality
Development and Application of Detection Methods for Reactive Oxygen Species and Antioxidants submission deadline 31 Dec 2025 | Viewed by 296 | Submission Open
Keywords: antioxidant extraction; antioxidant assay; sensors for reactive oxygen species (ROS); ROS scavenger assays; biological samples; oxidative stress status; nutritional value; food analysis; bioassays; enzymatic assays; redox cycle; cell imaging
(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)
Oxidative Stress and Mitochondrial Dysfunction in Metabolic Disorders
edited by , and Hugo J Alves-Figueiredo
submission deadline 31 Dec 2025 | 1 articles | Viewed by 281 | Submission Open
Keywords: metabolic diseases; oxidative stress; mitochondrial dysfunction; antioxidant therapies; lifestyle interventions; gene therapies; mitochondrial transfer therapies
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Natural Products and Peptides in Cosmetics submission deadline 31 Dec 2025 | Viewed by 251 | Submission Open
Keywords: cosmetics; herbal extracts; natural products; peptides; synthesis; isolation; oxidative stress; emulsions; nanoparticles; fibroblasts; ageing
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Antioxidants for Skin Health—2nd Edition
edited by Rubia Casagrande
submission deadline 31 Dec 2025 | Viewed by 223 | Submission Open
Keywords: skin inflammation; cytokine; skin oxidative stress; Nrf2; reduced glutathione; ultraviolet irradiation; drug delivery; flavonoid; terpenes; specialized pro-resolution lipid mediators
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
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