New Strategies in Preventing Inflammatory and/or Oxidative Stress-Induced Damages in Ischemia-Reperfusion Injury, 2nd Edition
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 235
Special Issue Editors
Interests: liver regeneration; liver metastasis; magnetic hyperthermia; nanoparticles; ischemia-reperfusion injury; antioxidants therapy; experimental surgery
Special Issues, Collections and Topics in MDPI journals
Interests: liver regeneration; liver metastasis; magnetic hyperthermia; nanoparticles; ischemia-reperfusion injury; antioxidants therapy; experimental surgery
Special Issues, Collections and Topics in MDPI journals
Interests: tissue engineering; regenerative medicine; oxidative stress; ischemia-reperfusion injury; antioxidants therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleague,
Ischemia–reperfusion injury (IRI) is a critical condition resulting from the sudden loss and subsequent restoration of blood supply to an organ or tissue, leading to significant cellular and tissue damage. This injury occurs due to a lack of oxygen and essential nutrients during ischemia, causing direct cellular harm through decreased ATP and pH levels and increased calcium. Upon reperfusion, the damage is exacerbated by the generation of reactive oxygen species (ROS), inflammatory cytokines, leukocyte recruitment, complement system activation, and changes in capillary permeability. IRI is associated with various clinical scenarios, including cardiovascular surgeries, organ transplants, orthopedic procedures, and conditions like vascular spasms or thromboembolism. It affects multiple organs, such as the heart, retina, and intestines, and is implicated in long-term neurological damage in newborns suffering from perinatal hypoxia.
The Special Issue "New Strategies in Preventing Inflammatory and/or Oxidative-Stress-Induced Damages in Ischemia–Reperfusion Injury, 2nd Edition" builds on the fruitful first edition, which is available at https://www.mdpi.com/si/155268.
Continuing our commitment to advancing IRI research, this edition aims to gather the latest developments in therapies designed to reduce or prevent ischemia–reperfusion injury across various organs and systems. We invite contributions that investigate the application of natural and synthetic antioxidants, stem cells, and their derivatives (such as secretome) as therapeutic strategies.
Submissions may include original research and comprehensive reviews that address (i) a better understanding of the underlying molecular processes involved in IRI; (ii) the progress and current status of the therapeutic management of IRI; and (iii) aspects related to the preservation of the organ function, due to their special clinical interest.
Dr. Borja Herrero de la Parte
Dr. Ignacio García-Alonso
Prof. Dr. Ana Alonso-Varona
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- ischemia–reperfusion injury
- reactive oxygen species
- hypoxia
- antioxidants
- therapeutic management
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