The Implication of Oxidative Stress on Human Aging and Associated Pathologies
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 2622
Special Issue Editors
Interests: aging; Alzheimer’s disease; pharmacology; genetics; neuroscience; biomedical science; inflammation; immunology; diagnosis; neutrophils; pathogenesis; phagocytes; chemotaxis; oxidative stress
Special Issues, Collections and Topics in MDPI journals
Interests: investigation of basic research in homeopathy; the use of high diluted substances on immune cells; the cellular and molecular biology of plant derived compounds on inflammation; the cellular biology of basophils
Special Issue Information
Dear Colleagues,
Aging is a complex biological process that may be closely linked with various age-related diseases, including neurodegenerative disorders, cardiovascular diseases, diabetes, and cancer. A high number of scientific reports support the evidence that oxidative stress, a condition often characterized by an imbalance between the production of reactive oxygen species (ROS) and the body's antioxidant defense mechanisms, should play a pivotal role in the progression of these aging-related diseases.
Research on the activity of low-dose toxicants, such as xenobiotics and ozone, which usually work following hormetic or non-linear mechanisms, is rapidly increasing, creating new hopes and opportunities for the scientific research in this field, thereby providing experts with novel chances in attempting new therapy approaches and certainty in enhancing the basic research on cell complexity and biology.
Evidence regarding the role of phytochemicals, xenobiotics, and ozone, the major antioxidant molecules, in addressing the biological basis of aging-related neurodegenerative disorders, is impacting this field of medicine.
This Special Issue aims to explore the multifaceted role of oxidative stress in the pathogenesis of age-related diseases, delving into the molecular mechanisms, signaling pathways, and potential therapeutic interventions, particularly focusing on the role of xenobiotic antioxidants. We invite contributions that investigate how oxidative stress influences cellular aging, promotes tissue degeneration, and contributes to chronic inflammation and metabolic dysfunction. Studies on antioxidant therapies, lifestyle interventions, and novel biomarkers for oxidative damage are particularly welcome.
Through this collection of research articles and reviews, we aspire to foster advancements in the prevention and treatment of age-related diseases, enhancing the quality of life for the aging population.
We invite you to submit your manuscripts, which we consider to be excellent opportunity to deeply comprehend these issues, preferably by 30 March 2025, by joining this endeavor and sending your availability to collaborate as well as your Abstract for which the deadline is 31 December 2024.
Prof. Dr. Giovanni Ricevuti
Prof. Dr. Salvatore Chirumbolo
Guest Editors
Manuscript Submission Information
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Keywords
- ROS
- dementia and Alzheimer
- aging
- cellular senescence
- senescent cells
- senolitic therapy
- glial cells
- inflammaging
- immunosenescence
- inflammation
- metaflammation
- inflammasoma
- NRF2 and NFKB
- DNA methylation
- glycomics
- metabolomics
- lipidomics
- anti-senescence therapy
- source of chronic inflammation in aging
- oxygen ozone therapy
- phytochemicals
- xenobiotics
- ozone
- antioxidant molecules
- nutrition
- anti-inflammatory drugs
- cardiovascular disease
- medicinal plants
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