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Phytotherapy in Veterinary Medicine

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 1559

Special Issue Editors


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Guest Editor
Pathophysiology Department, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 3-5 Manastur Street, 400372 Cluj-Napoca, Romania
Interests: phytotherapy; plant extracts; clinical pathology; physiopathology
Special Issues, Collections and Topics in MDPI journals

E-Mail Website1 Website2
Guest Editor
1. Faculty of Biology and Geology, Babeș-Bolyai University, 400006 Cluj-Napoca, Romania
2. National Institute for Research and Development of Isotopic and Molecular Technologies, 400293 Cluj-Napoca, Romania
Interests: hematology; oxidative stress; biochemistry; animal physiology

E-Mail Website
Guest Editor
1. Department of Molecular Biology and Biotechnologies, Babeș-Bolyai University, 400006 Cluj-Napoca, Romania
2. Institute of Biological Research, Branch of NIRDBS Bucharest, 400015 Cluj-Napoca, Romania
Interests: neuro-immune interactions; globins; oxygen-sensing mechanisms; targeted biochemistry; phytochemistry

Special Issue Information

Dear Colleagues,

Phytotherapy is the usage of plant-based products as medications to cure or to prevent disease. Since ancient times, herbal extracts were used not only to alleviate human disease, but also for curing animals. Nowadays, a high number of studies used animal models to prove the efficiency of various plant compounds; however, the effective use of phytotherapy in veterinary medicine is still undervalued. Why veterinary practitioners are less interested in phytotherapy remains an open question, but we appreciate that there is a significant potential for phytotherapy in both pet animal medicine and organic/bio farming animal breading.

This Special Issue aims to promote phytotherapeutic remedies in veterinary medicine; therefore, we welcome original studies and reviews focusing for phytotherapy in various fields of veterinary medicine, veterinary applied microbiology, plant compounds toxicology, plant-based pharmacology, improvement feed strategies in veterinary medicine, or other related aspects.

Prof. Dr. Bogdan Sevastre
Dr. Anca-Daniela Stoica Farcaș
Dr. Vlad-Alexandru Toma
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • translational phytotherapy
  • veterinary medicine
  • oxidative stress
  • phytocompounds toxicology
  • molecular metabolism

Published Papers (1 paper)

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Research

12 pages, 2114 KiB  
Article
Chemoprotective Effect of Plantago sempervirens Crantz Extract on Ovarian Structure and Folliculogenesis
by Anca D. Stoica, Bogdan Sevastre, Maria Suciu, Alina Elena Pârvu, Marcel Pârvu, Vlad Alexandru Toma, Ioana Roman and Camelia Dobre
Appl. Sci. 2023, 13(5), 3134; https://doi.org/10.3390/app13053134 - 28 Feb 2023
Viewed by 984
Abstract
Alkylating agents such as cyclophosphamide (CPA) are commonly used in cytotoxic or immunosuppressive therapies for different types of diseases. One of the main secondary effects of such therapy is the reduction in follicular reserve, targeting the primordial follicles. The aim of this study [...] Read more.
Alkylating agents such as cyclophosphamide (CPA) are commonly used in cytotoxic or immunosuppressive therapies for different types of diseases. One of the main secondary effects of such therapy is the reduction in follicular reserve, targeting the primordial follicles. The aim of this study was to investigate the antioxidant and protective effects of Plantago sempervirens extract on the follicular pool. The experiment was performed on Wistar female rats, for 21 days. They were divided into five groups according to the treatment they received (Control, CPA (200 mg/kg BW), P. sempervirens extract in three different doses—25/50/100 dw/mL ethanol extract (5 mL/kg BW)). The investigations regarded enzymatic and non-enzymatic nitro-oxidative stress, hormone levels (FSH and estrogen), TEM sections of the ovaries, and oestrus cycle monitorization. CPA strongly increased the oxidative stress (TOS—32.8 mmol H2O2/L; NO—68.60 μmol/L; OSI—6.82), alongside a depletion of FSH and a blockage of the oestrus cycle in the metestrus phase. The follicular pool was strongly depleted during CPA exposure, but FSH concentration and the TEM images of the cells revealed a significant improvement after treatment, as the dose increases (P3). Therefore, these findings reveal that P. sempervirens therapy could have a potential protective effect against CPA-induced acute damages in the ovaries, as well as maintaining a functional oestrus cycle. Full article
(This article belongs to the Special Issue Phytotherapy in Veterinary Medicine)
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