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Nutrition and Health for the Aging Population

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Food Science and Technology".

Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 3007

Special Issue Editor


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Guest Editor
Johann-Friedrich-Blumenbach-Institute for Zoology and Anthropology, Faculty of Biology and Psychology, Georg-August-University of Göttingen, Am Türmchen 3, 33332 Gütersloh, Germany
Interests: amino acids; arginine; biochemistry; melatonin; mitochondria; metabolism; pharmacology; physiology; supplementation
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Special Issue Information

Dear Colleagues,

The demographic transition with the exponentially growing population of elderly people poses a great challenge to science and research. Age-associated metabolic dysfunction resulting in oxidative stress and inflammation is a dominant risk factor for many chronic and degenerative disorders and diseases. The progressive increase in healthcare costs for non-communicable diseases and the increase in morbidity and mortality with advanced age can be attributed to a great extent to the lack of appropriate nutritional support and the accumulative bioenergetic burden supposed upon the target population by the western diet that is usually rich in sugar, fat, and salt, but poor in antioxidants, fibers, and vegan proteins. The availability of bioenergetic resources determines the potential to adapt and survive. Nutrition constitutes a decisive factor in determining health and healthcare costs. The development of supplementation that targets the specific needs of the elderly has been proposed to improve health by supplying sufficient macro and micronutrients. This Special Issue explores current approaches to establish a superior supplementation using whole food, food, and food ingredients of exceptionally high nutrient density. Product development that demonstrates how such supplementation can exert broad positive effects on health in the target population is welcome and we aim to discuss the emerging concepts to improve nutrition and health by supplementation.

Dr. Burkhard Poeggeler
Guest Editor

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Keywords

  • aging
  • amino acids
  • antioxidants
  • fibers
  • food
  • health
  • nutrients
  • product development
  • proteins
  • supplementation

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Published Papers (1 paper)

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Research

11 pages, 1697 KiB  
Article
Benincasa hispida Extract Prevents Ovariectomy-Induced Osteoporosis in Female ICR Mice
by Sun-Il Choi, Xionggao Han, Xiao Men, Se-Jeong Lee, Geon Oh, Ye-Eun Choi, Jung-Mo Yang, Ju-Hyun Cho and Ok-Hwan Lee
Appl. Sci. 2023, 13(2), 832; https://doi.org/10.3390/app13020832 - 7 Jan 2023
Cited by 4 | Viewed by 2050
Abstract
With the increase in bone metabolic diseases owing to the aging of the global population, interest in functional food ingredients for improving bone health is increasing. This study aimed to determine the anti-osteoporosis effect of Benincasa hispida extract (BHE, HR1901-W) and 2-furoic acid [...] Read more.
With the increase in bone metabolic diseases owing to the aging of the global population, interest in functional food ingredients for improving bone health is increasing. This study aimed to determine the anti-osteoporosis effect of Benincasa hispida extract (BHE, HR1901-W) and 2-furoic acid in ovariectomy (OVX)-induced osteoporosis in female ICR mice. Thirty-five female ICR mice underwent OVX or sham operation and were randomized into seven groups of five animals as follows: normal, sham, OVX, OVX with genistein (10 mg/kg), 2-furoic acid (20 mg/kg), LBHE (100 mg/kg), and HBHE (200 mg/kg). After an 8-week treatment period, femur and blood samples were collected from mice. Bone density and bone formation markers were significantly recovered in the 2-furoic acid and HBHE supplementation groups compared with those in the OVX group. In addition, bone resorption markers were increased in OVX mice, whereas they were significantly decreased in the OVX + 2-furoic acid and HBHE supplementation groups. This study suggests that BHE supplementation prevents bone resorption and promotes bone formation in OVX mice. These findings indicate that BHE could be used as a promising natural means to prevent OVX-induced osteoporosis and bone metabolic diseases. Full article
(This article belongs to the Special Issue Nutrition and Health for the Aging Population)
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