Design of New Organometallic Bioactive Molecules
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Chemical and Molecular Sciences".
Deadline for manuscript submissions: closed (10 October 2021) | Viewed by 4108
Special Issue Editor
Special Issue Information
Dear Colleagues,
A plausible definition for bio-organometallic compounds invokes the presence of one M–C bond at the very least, which connects low-valent metal fragments with biomolecules or behaves as a bioactive species. However, examples such as Fe-haeme type, Molibdopterin or Cobalamines do not globally fit these requirements, particularly concerning oxidation state. The difficulty in seeking a convincing global definition for this attractive branch of chemistry reveals wider perspectives to stimulate the disclosure of new unexplored frontiers in the field of living beings’ secrets.
Prof. Dr. Silvia Bordoni
Guest Editor
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Keywords
- Ligand to metal bonding
- Transition metal active sites
- Main group active sites
- Enzymatic mechanisms
- Structure–activity relationship
- Activation of carbon dioxide
- Dehydrogenase
- Methanogenesis
- Variability and flexibility in ligand coordination
- Organometallics in therapy and diagnosis
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