Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.3
2.5
Journals
Applied Sciences
Special Issues
Photoacoustic Tomography (PAT) II
applsci-logo
Submit to Applied Sciences Review for Applied Sciences Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Photoacoustic Tomography (PAT) II

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Optics and Lasers".

Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 12174

Special Issue Editors

Prof. Dr. Xueding Wang

E-Mail Website
Guest Editor
Department of Biomedical Engineering, University Michigan Ann Arbor, Ann Arbor, MI, USA
Interests: photoacoustic imaging; biomedical ultrasound
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Xinmai Yang

E-Mail Website
Guest Editor
Department of Mechanical Engineering, University of Kansas, Lawrence, KS, USA
Interests: photoacoustic imaging; biomedical ultrasound
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Xose Luis Dean-Ben

E-Mail Website
Guest Editor
Institute for Biological and Medical Imaging, Helmholtz Zentrum Munich & Technical University of Munich, 81675 Munich, Germany
Interests: photoacoustic imaging; biomedical ultrasound
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Photoacoustic (or optoacoustic) imaging, including photoacoustic tomography (PAT) and photoacoustic microscopy (PAM), is an emerging imaging modality with great clinical potential. PAI’s deep tissue penetration and fine spatial resolution also hold great promise for visualizing physiology and pathology at the molecular level. PAI combines optical contrast with ultrasonic resolution and is capable of imaging at depths of up to 7 cm with a real-time scalable spatial resolution of 10 to 500 µm. PAI has demonstrated applications in brain imaging and cancer imaging such as breast cancer, prostate cancer, oval cancer, etc. This Special Issue focuses on the novel technological developments and preclinical and clinical biomedical applications of PAI. Topics include but are not limited to:

  • Brain imaging;
  • Cancer imaging;
  • Image reconstruction;
  • Quantitative imaging;
  • Light source and delivery for PAI;
  • Photoacoustic detector;
  • Nanoparticles designed for PAI;
  • Photoacoustic molecular imaging;
  • Photoacoustic spectroscopy.

Prof. Dr. Xueding Wang
Prof. Dr. Xinmai Yang
Dr. Xose Luis Dean-Ben
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • photoacoustic imaging
  • photoacoustic tomography
  • photoacoustic microscopy
  • molecular imaging
  • laser
  • ultrasound
  • nanoparticle
  • cancer
  • brain

Published Papers (4 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

12 pages, 3318 KiB  
Article
Ultrasound-Guided Detection and Segmentation of Photoacoustic Signals from Bone Tissue In Vivo
by Ting Feng, Yunhao Zhu, Chengcheng Liu, Sidan Du, Dean Ta, Qian Cheng and Jie Yuan
Appl. Sci. 2021, 11(1), 19; https://doi.org/10.3390/app11010019 - 22 Dec 2020
Cited by 8 | Viewed by 2740
Abstract
Photoacoustic (PA) techniques provide optical absorption contrast and spatial information at an ultrasound resolution in deep biological tissues. Among the greatest challenges encountered in the PA examination of bone is the analysis of trabecular bone, which holds key chemical and physical information required [...] Read more.
Photoacoustic (PA) techniques provide optical absorption contrast and spatial information at an ultrasound resolution in deep biological tissues. Among the greatest challenges encountered in the PA examination of bone is the analysis of trabecular bone, which holds key chemical and physical information required for bone health assessments. Ultrasound detection is naturally registered with PA detection; therefore, in this study, we propose ultrasound guidance for the PA detection of trabecular bone. We perform both numerical simulations and an in vivo experiment on a human subject to investigate the possibility of ultrasound-guided detection and segmentation of photoacoustic signals from bone tissue in vivo in a non-invasive manner. The results obtained from the simulation and in vivo experiment suggest that the ultrasound-guided PA method can distinguish PA signals from trabecular and cortical bones as well as from the overlying soft tissue. Considering that the PA technique is non-ionizing and non-invasive, it holds potential for clinical bone health assessment. Full article
(This article belongs to the Special Issue Photoacoustic Tomography (PAT) II)
►▼ Show Figures

Figure 1

11 pages, 3710 KiB  
Article
Bone Chemical Composition Assessment with Multi-Wavelength Photoacoustic Analysis
by Ting Feng, Yunhao Zhu, Kenneth M. Kozloff, Basma Khoury, Yejing Xie, Xueding Wang, Meng Cao, Jie Yuan, Dean Ta and Qian Cheng
Appl. Sci. 2020, 10(22), 8214; https://doi.org/10.3390/app10228214 - 19 Nov 2020
Cited by 7 | Viewed by 3280
Abstract
In this study, the feasibility of assessing the chemical composition in bone using the multi-wavelength photoacoustic analysis (MWPA) method was investigated. By illuminating a bone specimen using laser light with a wavelength tunable over an optical spectrum from 680 nm to 950 nm, [...] Read more.
In this study, the feasibility of assessing the chemical composition in bone using the multi-wavelength photoacoustic analysis (MWPA) method was investigated. By illuminating a bone specimen using laser light with a wavelength tunable over an optical spectrum from 680 nm to 950 nm, the optical absorption spectrum of the bone was acquired. Then, with the optical absorption spectra of all the optically absorbing chemical components in the bone known, a spectral unmixing procedure was performed to quantitatively assess the relative content of each chemical component. The experimental results from porcine rib bones demonstrated that the contents of the chemical components, including not only non-organic materials such as minerals and water but also organic materials including oxygenated hemoglobin, deoxygenated hemoglobin, lipid, and collagen, can all be assessed by MWPA. As the chemical composition in the bone is directly associated with functional and metabolic activities, the finding from this study suggests that the MWPA method could offer a new diagnostic tool for the non-invasive evaluation of bone health. Full article
(This article belongs to the Special Issue Photoacoustic Tomography (PAT) II)
►▼ Show Figures

Figure 1

8 pages, 1391 KiB  
Article
Coregistration and Spatial Compounding of Optoacoustic Cardiac Images via Fourier Analysis of Four-Dimensional Data
by Hongtong Li, Ivana Ivankovic, Jiao Li, Daniel Razansky and Xosé Luís Deán-Ben
Appl. Sci. 2020, 10(18), 6254; https://doi.org/10.3390/app10186254 - 9 Sep 2020
Cited by 4 | Viewed by 1867
Abstract
Volumetric optoacoustic tomography has been shown to provide unprecedented capabilities for ultrafast imaging of cardiovascular dynamics in mice. Three-dimensional imaging rates in the order of 100 Hz have been achieved, which enabled the visualization of transient cardiac events such as arrhythmias or contrast [...] Read more.
Volumetric optoacoustic tomography has been shown to provide unprecedented capabilities for ultrafast imaging of cardiovascular dynamics in mice. Three-dimensional imaging rates in the order of 100 Hz have been achieved, which enabled the visualization of transient cardiac events such as arrhythmias or contrast agent perfusion without the need for retrospective gating. The fast murine heart rates (400–600 beats per minute) yet impose limitations when it comes to compounding of multiple frames or accurate registration of multi-spectral data. Herein, we investigate on the capabilities of Fourier analysis of four-dimensional data for coregistration of independent volumetric optoacoustic image sequences of the heart. The fundamental frequencies and higher harmonics of respiratory and cardiac cycles could clearly be distinguished, which facilitated efficient retrospective gating without additional readings. The performance of the suggested methodology was successfully demonstrated by compounding cardiac images acquired by raster-scanning of a spherical transducer array as well as by unmixing of oxygenated and deoxygenated hemoglobin from multi-spectral optoacoustic data. Full article
(This article belongs to the Special Issue Photoacoustic Tomography (PAT) II)
►▼ Show Figures

Figure 1

5 pages, 1917 KiB  
Communication
Photoacoustic Imaging of Tattoo Inks: Phantom and Clinical Evaluation
by Eftekhar Rajab Bolookat, Laurie J. Rich, Gyorgy Paragh, Oscar R. Colegio, Anurag K. Singh and Mukund Seshadri
Appl. Sci. 2020, 10(3), 1024; https://doi.org/10.3390/app10031024 - 4 Feb 2020
Cited by 5 | Viewed by 3612
Abstract
Photoacoustic imaging (PAI) is a novel hybrid imaging modality that provides excellent optical contrast with the spatial resolution of ultrasound in vivo. The method is widely being investigated in the clinical setting for diagnostic applications in dermatology. In this report, we illustrate the [...] Read more.
Photoacoustic imaging (PAI) is a novel hybrid imaging modality that provides excellent optical contrast with the spatial resolution of ultrasound in vivo. The method is widely being investigated in the clinical setting for diagnostic applications in dermatology. In this report, we illustrate the utility of PAI as a non-invasive tool for imaging tattoos. Ten different samples of commercially available tattoo inks were examined for their optoacoustic properties in vitro. In vivo PAI of an intradermal tattoo on the wrist was performed in a healthy human volunteer. Black/gray, green, violet, and blue colored pigments provided higher levels of PA signal compared to white, orange, red, and yellow pigments in vitro. PAI provided excellent contrast and enabled accurate delineation of the extent of the tattoo in the dermis. Our results reveal the photoacoustic properties of tattoo inks and demonstrate the potential clinical utility of PAI for intradermal imaging of tattoos. PAI may be useful as a clinical adjunct for objective preoperative evaluation of tattoos and potentially to guide/monitor laser-based tattoo removal procedures. Full article
(This article belongs to the Special Issue Photoacoustic Tomography (PAT) II)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-4
Back to TopTop