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Advances in Signal and Image Processing for Biomedical Applications

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 5040

Special Issue Editors

School of Automation, University of Electronic Science and Technology of China, Chengdu, China
Interests: computer vision; surgical robots; medical image processing
Special Issues, Collections and Topics in MDPI journals
School of Computer Science and Technology, East China Normal University, Shanghai 200062, China
Interests: multi-agent reinforcement learning and applications
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
College of Electronic Information and Automation, Tianjin University of Science and Technology, Tianjin 300000, China
Interests: medical image processing; pattern recognition; electrical tomography

Special Issue Information

Dear Colleagues,

This Special Issue aims to highlight recent advances in signal and image processing techniques in medical applications. Over the past decade, deep learning techniques have revolutionized the processing of signals, images, and videos. Deep-learning-based algorithms have achieved great success, especially in natural language processing and tasks related to image and vision, such as classification, recognition, detection, segmentation, and reconstruction. The progress in deep learning technology is largely driven by the improvement of computing power (especially parallel computing power) and the convenience of building large-scale training data sets with the Internet. However, in the field of medical applications, deep learning still faces many challenges, mainly including: 1) the cost of medical data collection and labeling is high; 2) the data volume of medical data (e.g., high-resolution CT) is large, which usually requires more efficient processing algorithms; and 3) the black-box nature of deep learning methods leads to their lack of interpretability in medical tasks, and it is difficult to gain the trust of doctors, regulators and patients.

This Special Issue welcomes all recent research works in signal and image processing for applications in medicine, especially those that fuse traditional and deep learning techniques, unsupervised or self-supervised methods, and interpretable deep learning models built for medical purposes. Potential topics in this collection include, but are not limited to, the following topics:

  • Medical image (e.g., CT, MRI, ultrasound) processing
  • Surgical vision (applications of computer vision in surgery)
  • Medical signal processing
  • Medical image reconstruction
  • Medical image classification, detection, localization and segmentation
  • Intelligent diagnostic system based on medical signals, image and data

Dr. Bo Yang
Dr. Bo Jin
Prof. Dr. Xiaoyan Chen
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (3 papers)

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Research

22 pages, 5027 KiB  
Article
Reconstructing Nerve Structures from Unorganized Points
by Jelena Kljajić, Goran Kvaščev and Željko Đurović
Appl. Sci. 2023, 13(20), 11421; https://doi.org/10.3390/app132011421 - 18 Oct 2023
Viewed by 743
Abstract
Realistic sensory feedback is paramount for amputees as it improves prosthetic limb control and boosts functionality, safety, and overall quality of life. This sensory restoration relies on the direct electrostimulation of residual peripheral nerves. Computational models are instrumental in simulating these neurostimulation effects, [...] Read more.
Realistic sensory feedback is paramount for amputees as it improves prosthetic limb control and boosts functionality, safety, and overall quality of life. This sensory restoration relies on the direct electrostimulation of residual peripheral nerves. Computational models are instrumental in simulating these neurostimulation effects, offering solutions to the complexities tied to extensive animal/human trials and costly materials. Central to these models is the detailed mapping of nerve geometry, necessitating the delineation of internal nerve structures, such as fascicles, across various cross-sections. In our modeling process, we faced the challenge of organizing an originally unstructured set of points into coherent contours. We introduced a parameter-free curve-reconstruction algorithm that combines valley-seeking clustering, an adaptive Kalman filter, and the nearest neighbor classification technique. While intuitively simple for humans, the task of reconstructing multiple open and/or closed lines with pronounced corners from a nonuniform point set is daunting for many algorithms. Additionally, the precise differentiation of adjacent curves, commonly encountered in realistic nerve models, remains a formidable challenge even for top-tier algorithms. Our proposed method adeptly navigates the complexities inherent to nerve structure reconstruction. While our algorithm is chiefly designed for closed curves, as dictated by nerve geometry, we believe it can be reconfigured with appropriate code adjustments to handle open curves. Beyond neuroprosthetics, our proposed model has the potential to be applied and spark innovations in biomedicine and a variety of other fields. Full article
(This article belongs to the Special Issue Advances in Signal and Image Processing for Biomedical Applications)
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14 pages, 3150 KiB  
Article
Left Ventricular Ejection Time Estimation from Blood Pressure and Photoplethysmography Signals Based on Tidal Wave
by Lucian Evdochim, Dragoș Dobrescu, Lidia Dobrescu, Silviu Stanciu and Stela Halichidis
Appl. Sci. 2023, 13(19), 11025; https://doi.org/10.3390/app131911025 - 6 Oct 2023
Cited by 1 | Viewed by 1649
Abstract
Left ventricular ejection time (LVET) is an important parameter for assessing cardiovascular disorders. In a medical office, it is typically measured using the Tissue Doppler Imaging technique, but new wearable devices have led to a growing interest in integrating this parameter into them, [...] Read more.
Left ventricular ejection time (LVET) is an important parameter for assessing cardiovascular disorders. In a medical office, it is typically measured using the Tissue Doppler Imaging technique, but new wearable devices have led to a growing interest in integrating this parameter into them, increasing accessibility to personalized healthcare for users and patients. In the cardiovascular domain, photoplethysmography (PPG) is a promising technology that shares two distinctive features with invasive arterial blood pressure (ABP) tracing: the tidal wave (TDW) and the dicrotic wave (DCW). In the early years of cardiovascular research, the duration of the dicrotic point was initially linked to the ending phase of left ventricular ejection. Subsequent studies reported deviations from the initial association, suggesting that the ejection period is related to the tidal wave feature. In this current study, we measured left ventricular ejection time in both ABP and PPG waveforms, considering recent research results. A total of 27,000 cardiac cycles were analyzed for both afore-mentioned signals. The reference value for ejection time was computed based on the T-wave segment duration from the electrocardiogram waveform. In lower blood pressure, which is associated with decreased heart contractility, the results indicated an underestimation of −29 ± 19 ms in ABP and an overestimation of 18 ± 31 ms in PPG. On the other side of the spectrum, during increased contractility, the minimum errors were −3 ± 18 ms and 4 ± 33 ms, respectively. Since the tidal wave feature is strongly affected by arterial tree compliance, the population evaluation results indicate a Pearson’s correlation factor of 0.58 in the ABP case, and 0.53 in PPG. These findings highlight the need for advanced compensation techniques, in particular for PPG assessment, to achieve clinical-grade accuracy. Full article
(This article belongs to the Special Issue Advances in Signal and Image Processing for Biomedical Applications)
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24 pages, 6705 KiB  
Article
Three-Dimensional Modeling of Heart Soft Tissue Motion
by Mingzhe Liu, Xuan Zhang, Bo Yang, Zhengtong Yin, Shan Liu, Lirong Yin and Wenfeng Zheng
Appl. Sci. 2023, 13(4), 2493; https://doi.org/10.3390/app13042493 - 15 Feb 2023
Cited by 41 | Viewed by 1849
Abstract
The modeling and simulation of biological tissue is the core part of a virtual surgery system. In this study, the geometric and physical methods related to soft tissue modeling were investigated. Regarding geometric modeling, the problem of repeated inverse calculations of control points [...] Read more.
The modeling and simulation of biological tissue is the core part of a virtual surgery system. In this study, the geometric and physical methods related to soft tissue modeling were investigated. Regarding geometric modeling, the problem of repeated inverse calculations of control points in the Bezier method was solved via re-parameterization, which improved the calculation speed. The base surface superposition method based on prior information was proposed to make the deformation model not only have the advantages of the Bezier method but also have the ability to fit local irregular deformation surfaces. Regarding physical modeling, the fitting ability of the particle spring model to the anisotropy of soft tissue was improved by optimizing the topological structure of the particle spring model. Then, the particle spring model had a more extensive nonlinear fitting ability through the dynamic elastic coefficient parameter. Finally, the secondary modeling of the elastic coefficient based on the virtual body spring enabled the model to fit the creep and relaxation characteristics of biological tissue according to the elongation of the virtual body spring. Full article
(This article belongs to the Special Issue Advances in Signal and Image Processing for Biomedical Applications)
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