Sickle Cell Disease: Molecular Mechanisms, Pathogenesis and Therapies
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Medical Biology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 21
Special Issue Editor
Special Issue Information
Dear Colleagues,
The recent advances in the understanding of the regulation of genes and proteins in the pathophysiology of sickle cell disease (SCD) using genomic and proteomic technologies underline the development of various treatment modalities, including the implementation of gene therapy strategies for curing sickle cell disease. The Special Issue on "Sickle Cell Disease: Molecular Mechanisms, Pathogenesis and Therapies" will publish contemporary findings of pathophysiology, molecular mechanisms of disease progression and treatment, new drug development, and molecular, cellular, and gene therapy. Therefore, we invite you to submit your original research articles and reviews in this Special Issue on SCD research. We look forward to receiving your contributions to this Special Issue.
Dr. Chithra Palani
Guest Editor
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Keywords
- SCD
- anemia
- erythrocyte development
- erythroid progenitors
- CD34 cells
- vaso-occlusion
- pain crisis
- hemolysis
- oxidative stress
- sickling
- inflammation
- ER stress
- fetal hemoglobin
- hematopoiesis
- ischemia and tissue damage
- organ damage
- drug development
- SCD diagnosis
- gene therapy
- cell therapy
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