Metabolic Interactions between the Gut Microbiome and Host

Dear Colleagues,

The symbiotic relationship between the gut microbiota and the host imparts metabolic, immune, and intestinal protective functions to healthy individuals. This interaction is largely determined by factors such as nutritional status and lifestyle habits. Diet is a major driver in shaping the gut microecosystem, which provides selective growth advantages for specific species of bacteria. Long-term dietary intervention can regulate the composition and function of intestinal microbiota in both humans and animals. Simultaneously, the metabolic activity of gut microbes also has an important impact on host health and the metabolic phenotype of the host, which can be beneficial or harmful. Gut microbiota imbalance is closely related to the occurrence and development of chronic metabolic diseases, such as diabetes, obesity, inflammatory bowel disease, cardiovascular disease, depression, tumor, and so on. Therefore, it is vital to reveal the strain specificity that produces microbial metabolites, which will facilitate the identification and discovery of strains or specific metabolites for diseases for therapeutic purposes.

This Special Issue focuses on “Metabolic Interactions between the Gut Microbiome and Host” and welcomes the submission of original research and review articles focusing on the causal relationship and its intrinsic mechanisms between the gut microbiome and the host; however, research on new methods and technologies employed for studying key bacteria and their specific molecules, microbial heterogeneity, that will help us to understand the gut microbiota in depth is also welcome. This Special Issue will enlighten readers about new discoveries, advances, and developments in microbiome-related disease therapeutics.

Dr. Weiwei Wang
Dr. Yun Ji
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• gut microbiome
• host
• metabolome
• microbial heterogeneity
• biomolecules